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    Results: 1 to 20 of 286

    1.

    Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells.

    Eitel K, Staiger H, Rieger J, Mischak H, Brandhorst H, Brendel MD, Bretzel RG, Häring HU, Kellerer M.

    Diabetes. 2003 Apr;52(4):991-7.PMID: 12663471 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    [Apoptosis induced by free fatty acids]

    Eitel K, Staiger H, Brendel MD, Brandhorst H, Bretzel RG, Häring HU, Kellerer M.

    Med Klin (Munich). 2003 Apr 25;98(5):248-52. German. PMID: 12721668 [PubMed - indexed for MEDLINE]Related articles

    3.

    Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

    Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G, Rabuazzo AM, Vigneri R, Purrello M, Purrello F.

    Metabolism. 2002 Oct;51(10):1340-7.PMID: 12370856 [PubMed - indexed for MEDLINE]Related articles

    4.

    Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).

    Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ.

    J Mol Endocrinol. 2003 Jun;30(3):271-86.PMID: 12790799 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G.

    Mishra R, Simonson MS.

    Cardiovasc Diabetol. 2005 Jan 10;4(1):2.PMID: 15642122 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function.

    Maedler K, Spinas GA, Dyntar D, Moritz W, Kaiser N, Donath MY.

    Diabetes. 2001 Jan;50(1):69-76.PMID: 11147797 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    PKC-delta is an apoptotic lamin kinase.

    Cross T, Griffiths G, Deacon E, Sallis R, Gough M, Watters D, Lord JM.

    Oncogene. 2000 May 4;19(19):2331-7.PMID: 10822384 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity.

    Pagliassotti MJ, Wei Y, Wang D.

    Endocrinology. 2007 Jul;148(7):3338-45. Epub 2007 Apr 12.PMID: 17431009 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function.

    Maedler K, Oberholzer J, Bucher P, Spinas GA, Donath MY.

    Diabetes. 2003 Mar;52(3):726-33.PMID: 12606514 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Different role of saturated and unsaturated fatty acids in beta-cell apoptosis.

    Eitel K, Staiger H, Brendel MD, Brandhorst D, Bretzel RG, Häring HU, Kellerer M.

    Biochem Biophys Res Commun. 2002 Dec 20;299(5):853-6.PMID: 12470657 [PubMed - indexed for MEDLINE]Related articles

    11.

    Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells.

    Yu HY, Inoguchi T, Kakimoto M, Nakashima N, Imamura M, Hashimoto T, Umeda F, Nawata H.

    Diabetologia. 2001 May;44(5):614-20.PMID: 11380080 [PubMed - indexed for MEDLINE]Related articles

    12.

    Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure.

    Artwohl M, Lindenmair A, Roden M, Waldhäusl WK, Freudenthaler A, Klosner G, Ilhan A, Luger A, Baumgartner-Parzer SM.

    Atherosclerosis. 2009 Feb;202(2):351-62. Epub 2008 May 28.PMID: 18597758 [PubMed - indexed for MEDLINE]Related articles

    13.

    Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion.

    Littman ED, Pitchumoni S, Garfinkel MR, Opara EC.

    Pancreas. 2000 Apr;20(3):256-63.PMID: 10766451 [PubMed - indexed for MEDLINE]Related articles

    14.

    Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

    Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

    Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

    Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ.

    J Biol Chem. 2002 Dec 20;277(51):49676-84. Epub 2002 Oct 21.PMID: 12393870 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.

    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.

    Int J Oncol. 2004 Mar;24(3):591-608.PMID: 14767544 [PubMed - indexed for MEDLINE]Related articles

    17.

    Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition.

    Beeharry N, Chambers JA, Green IC.

    Apoptosis. 2004 Sep;9(5):599-607.PMID: 15314288 [PubMed - indexed for MEDLINE]Related articles

    18.

    Evidence that protein kinase Cdelta is not required for palmitate-induced cytotoxicity in BRIN-BD11 beta-cells.

    Welters HJ, Smith SA, Tadayyon M, Scarpello JH, Morgan NG.

    J Mol Endocrinol. 2004 Feb;32(1):227-35.PMID: 14766004 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.

    El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, Hardy S, Joly E, Dbaibo G, Rosenberg L, Prentki M.

    Endocrinology. 2003 Sep;144(9):4154-63.PMID: 12933690 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.

    Kaul S, Kanthasamy A, Kitazawa M, Anantharam V, Kanthasamy AG.

    Eur J Neurosci. 2003 Sep;18(6):1387-401.PMID: 14511319 [PubMed - indexed for MEDLINE]Related articles

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