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A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.

Frayling TM, Lindgren CM, Chevre JC, Menzel S, Wishart M, Benmezroua Y, Brown A, Evans JC, Rao PS, Dina C, Lecoeur C, Kanninen T, Almgren P, Bulman MP, Wang Y, Mills J, Wright-Pascoe R, Mahtani MM, Prisco F, Costa A, Cognet I, Hansen T, Pedersen O, Ellard S, Tuomi T, Groop LC, Froguel P, Hattersley AT, Vaxillaire M.

Diabetes. 2003 Mar;52(3):872-81.PMID: 12606533 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.

Kim SH, Ma X, Klupa T, Powers C, Pezzolesi M, Warram JH, Rich SS, Krolewski AS, Doria A.

Diabetes. 2003 Aug;52(8):2182-6.PMID: 12882939 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutation screening in 18 Caucasian families suggest the existence of other MODY genes.

Chèvre JC, Hani EH, Boutin P, Vaxillaire M, Blanché H, Vionnet N, Pardini VC, Timsit J, Larger E, Charpentier G, Beckers D, Maes M, Bellanné-Chantelot C, Velho G, Froguel P.

Diabetologia. 1998 Sep;41(9):1017-23.PMID: 9754819 [PubMed - indexed for MEDLINE]Related articles

Maturity-onset diabetes of the young: clinical heterogeneity explained by genetic heterogeneity.

Hattersley AT.

Diabet Med. 1998 Jan;15(1):15-24. Review. Erratum in: Diabet Med 1998 May;15(5):437. PMID: 9472859 [PubMed - indexed for MEDLINE]Related articles

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23.

Kim SH, Ma X, Weremowicz S, Ercolino T, Powers C, Mlynarski W, Bashan KA, Warram JH, Mychaleckyj J, Rich SS, Krolewski AS, Doria A.

Diabetes. 2004 May;53(5):1375-84.PMID: 15111509 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage and molecular scanning analyses of MODY3/hepatocyte nuclear factor-1 alpha gene in typical familial type 2 diabetes: evidence for novel mutations in exons 8 and 10.

Elbein SC, Teng K, Yount P, Scroggin E.

J Clin Endocrinol Metab. 1998 Jun;83(6):2059-65.PMID: 9626139 [PubMed - indexed for MEDLINE]Related articlesFree article

[MODY, a model of genotype/phenotype interactions in type 2 diabetes]

Velho G, Bellanné-Chantelot C, Timsit J.

Med Sci (Paris). 2003 Aug-Sep;19(8-9):854-9. Review. French. PMID: 14593617 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations in MODY genes are not common cause of early-onset type 2 diabetes in Mexican families.

Domínguez-López A, Miliar-García A, Segura-Kato YX, Riba L, Esparza-López R, Ramírez-Jiménez S, Rodríguez-Torres M, Canizales-Quinteros S, Cabrera-Vásquez S, Fragoso-Ontiveros V, Aguilar-Salinas CA, Altamirano-Bustamante N, Calzada-León R, Robles-Valdés C, Bravo-Ríos LE, Tusié-Luna MT.

JOP. 2005 May 10;6(3):238-45.PMID: 15883474 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.

Shaw JT, Lovelock PK, Kesting JB, Cardinal J, Duffy D, Wainwright B, Cameron DP.

Diabetes. 1998 Nov;47(11):1793-6.PMID: 9792550 [PubMed - indexed for MEDLINE]Related articlesFree article

Early-onset Type II diabetes mellitus in Italian families due to mutations in the genes encoding hepatic nuclear factor 1 alpha and glucokinase.

Gragnoli C, Cockburn BN, Chiaramonte F, Gorini A, Marietti G, Marozzi G, Signorini AM.

Diabetologia. 2001 Oct;44(10):1326-9.PMID: 11692182 [PubMed - indexed for MEDLINE]Related articles

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY).

Cao H, Shorey S, Robinson J, Metzger DL, Stewart L, Cummings E, Hegele RA.

Hum Mutat. 2002 Dec;20(6):478-9.PMID: 12442280 [PubMed - indexed for MEDLINE]Related articles

Half of clinically defined maturity-onset diabetes of the young patients in Denmark do not have mutations in HNF4A, GCK, and TCF1.

Johansen A, Ek J, Mortensen HB, Pedersen O, Hansen T.

J Clin Endocrinol Metab. 2005 Aug;90(8):4607-14. Epub 2005 May 31.PMID: 15928245 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.

Frayling TM, Evans JC, Bulman MP, Pearson E, Allen L, Owen K, Bingham C, Hannemann M, Shepherd M, Ellard S, Hattersley AT.

Diabetes. 2001 Feb;50 Suppl 1:S94-100.PMID: 11272211 [PubMed - indexed for MEDLINE]Related articles

Nine novel mutations in maturity-onset diabetes of the young (MODY) candidate genes in 22 Spanish families.

Barrio R, Bellanné-Chantelot C, Moreno JC, Morel V, Calle H, Alonso M, Mustieles C.

J Clin Endocrinol Metab. 2002 Jun;87(6):2532-9.PMID: 12050210 [PubMed - indexed for MEDLINE]Related articlesFree article

A rapid screening method for hepatocyte nuclear factor 1 alpha frameshift mutations; prevalence in maturity-onset diabetes of the young and late-onset non-insulin dependent diabetes.

Frayling TM, Bulman MP, Appleton M, Hattersley AT, Ellard S.

Hum Genet. 1997 Dec;101(3):351-4.PMID: 9439666 [PubMed - indexed for MEDLINE]Related articles

Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young.

Ellard S.

Hum Mutat. 2000 Nov;16(5):377-85. Review.PMID: 11058894 [PubMed - indexed for MEDLINE]Related articles

Genetic and clinical characterisation of maturity-onset diabetes of the young in Spanish families.

Costa A, Bescós M, Velho G, Chêvre J, Vidal J, Sesmilo G, Bellanné-Chantelot C, Froguel P, Casamitjana R, Rivera-Fillat F, Gomis R, Conget I.

Eur J Endocrinol. 2000 Apr;142(4):380-6.PMID: 10754480 [PubMed - indexed for MEDLINE]Related articlesFree article

[Molecular background and clinical characteristics of autosomal dominant type 2 diabetes mellitus]

Małecki M, Krolewski AS.

Przegl Lek. 2000;57 Suppl 3:13-8. Review. Polish. PMID: 11293229 [PubMed - indexed for MEDLINE]Related articles

A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q.

Vaxillaire M, Boccio V, Philippi A, Vigouroux C, Terwilliger J, Passa P, Beckmann JS, Velho G, Lathrop GM, Froguel P.

Nat Genet. 1995 Apr;9(4):418-23.PMID: 7795649 [PubMed - indexed for MEDLINE]Related articles

Phenotypic characteristics of early-onset autosomal-dominant type 2 diabetes unlinked to known maturity-onset diabetes of the young (MODY) genes.

Doria A, Yang Y, Malecki M, Scotti S, Dreyfus J, O'Keeffe C, Orban T, Warram JH, Krolewski AS.

Diabetes Care. 1999 Feb;22(2):253-61.PMID: 10333942 [PubMed - indexed for MEDLINE]Related articlesFree article