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    Results: 1 to 20 of 708

    1.

    Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.

    Obrosova IG, Minchenko AG, Vasupuram R, White L, Abatan OI, Kumagai AK, Frank RN, Stevens MJ.

    Diabetes. 2003 Mar;52(3):864-71.PMID: 12606532 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Sorbitol dehydrogenase overexpression potentiates glucose toxicity to cultured retinal pericytes.

    Amano S, Yamagishi S, Kato N, Inagaki Y, Okamoto T, Makino M, Taniko K, Hirooka H, Jomori T, Takeuchi M.

    Biochem Biophys Res Commun. 2002 Nov 29;299(2):183-8.PMID: 12437967 [PubMed - indexed for MEDLINE]Related articles

    3.

    Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.

    Obrosova IG, Pacher P, Szabó C, Zsengeller Z, Hirooka H, Stevens MJ, Yorek MA.

    Diabetes. 2005 Jan;54(1):234-42.PMID: 15616034 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.

    Drel VR, Pacher P, Ali TK, Shin J, Julius U, El-Remessy AB, Obrosova IG.

    Int J Mol Med. 2008 Jun;21(6):667-76.PMID: 18506358 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats.

    Obrosova IG, Minchenko AG, Marinescu V, Fathallah L, Kennedy A, Stockert CM, Frank RN, Stevens MJ.

    Diabetologia. 2001 Sep;44(9):1102-10.PMID: 11596663 [PubMed - indexed for MEDLINE]Related articles

    6.

    Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

    Obrosova IG, Minchenko AG, Frank RN, Seigel GM, Zsengeller Z, Pacher P, Stevens MJ, Szabó C.

    Int J Mol Med. 2004 Jul;14(1):55-64.PMID: 15202016 [PubMed - indexed for MEDLINE]Related articles

    7.

    Evaluation of an aldose reductase inhibitor on lens metabolism, ATPases and antioxidative defense in streptozotocin-diabetic rats: an intervention study.

    Obrosova IG, Fathallah L.

    Diabetologia. 2000 Aug;43(8):1048-55.PMID: 10990083 [PubMed - indexed for MEDLINE]Related articles

    8.

    An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.

    Obrosova IG, Van Huysen C, Fathallah L, Cao XC, Greene DA, Stevens MJ.

    FASEB J. 2002 Jan;16(1):123-5. Epub 2001 Nov 14.PMID: 11709499 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models.

    Obrosova IG, Drel VR, Kumagai AK, Szábo C, Pacher P, Stevens MJ.

    Diabetologia. 2006 Oct;49(10):2525-33. Epub 2006 Aug 1.PMID: 16896942 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    An aldose reductase inhibitor and aminoguanidine prevent vascular endothelial growth factor expression in rats with long-term galactosemia.

    Frank RN, Amin R, Kennedy A, Hohman TC.

    Arch Ophthalmol. 1997 Aug;115(8):1036-47.PMID: 9258227 [PubMed - indexed for MEDLINE]Related articles

    11.

    Long-term treatment with fidarestat suppresses the development of diabetic retinopathy in STZ-induced diabetic rats.

    Kato N, Yashima S, Suzuki T, Nakayama Y, Jomori T.

    J Diabetes Complications. 2003 Nov-Dec;17(6):374-9.PMID: 14583184 [PubMed - indexed for MEDLINE]Related articles

    12.

    Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes.

    Gilbert RE, Kelly DJ, Cox AJ, Wilkinson-Berka JL, Rumble JR, Osicka T, Panagiotopoulos S, Lee V, Hendrich EC, Jerums G, Cooper ME.

    Diabetologia. 2000 Nov;43(11):1360-7.PMID: 11126403 [PubMed - indexed for MEDLINE]Related articles

    13.

    Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats.

    Kato N, Mizuno K, Makino M, Suzuki T, Yagihashi S.

    Diabetes Res Clin Pract. 2000 Oct;50(2):77-85.PMID: 10960717 [PubMed - indexed for MEDLINE]Related articles

    14.

    Continuous inhibition of excessive polyol pathway flux in peripheral nerves by aldose reductase inhibitor fidarestat leads to improvement of diabetic neuropathy.

    Mizuno K, Kato N, Makino M, Suzuki T, Shindo M.

    J Diabetes Complications. 1999 May-Jun;13(3):141-50.PMID: 10509874 [PubMed - indexed for MEDLINE]Related articles

    15.

    Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.

    Drel VR, Pacher P, Stevens MJ, Obrosova IG.

    Free Radic Biol Med. 2006 Apr 15;40(8):1454-65. Epub 2006 Jan 31.PMID: 16631535 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney.

    Lee EA, Seo JY, Jiang Z, Yu MR, Kwon MK, Ha H, Lee HB.

    Kidney Int. 2005 May;67(5):1762-71.PMID: 15840023 [PubMed - indexed for MEDLINE]Related articles

    17.

    Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress.

    Yülek F, Or M, Ozoğul C, Isik AC, Ari N, Stefek M, Bauer V, Karasu C.

    Arch Med Res. 2007 Jul;38(5):503-11.PMID: 17560455 [PubMed - indexed for MEDLINE]Related articles

    18.

    Captopril inhibits glucose accumulation in retinal cells in diabetes.

    Zhang JZ, Gao L, Widness M, Xi X, Kern TS.

    Invest Ophthalmol Vis Sci. 2003 Sep;44(9):4001-5.PMID: 12939321 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: effects of stobadine and vitamin E.

    Ulusu NN, Sahilli M, Avci A, Canbolat O, Ozansoy G, Ari N, Bali M, Stefek M, Stolc S, Gajdosik A, Karasu C.

    Neurochem Res. 2003 Jun;28(6):815-23.PMID: 12718433 [PubMed - indexed for MEDLINE]Related articles

    20.

    Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.

    Kowluru RA, Atasi L, Ho YS.

    Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1594-9.PMID: 16565397 [PubMed - indexed for MEDLINE]Related articlesFree article

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