PubMed

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production.

Ye G, Metreveli NS, Ren J, Epstein PN.

Diabetes. 2003 Mar;52(3):777-83.PMID: 12606520 [PubMed - indexed for MEDLINE]Related articlesFree article

Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes.

Ye G, Metreveli NS, Donthi RV, Xia S, Xu M, Carlson EC, Epstein PN.

Diabetes. 2004 May;53(5):1336-43.PMID: 15111504 [PubMed - indexed for MEDLINE]Related articlesFree article

AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase.

Privratsky JR, Wold LE, Sowers JR, Quinn MT, Ren J.

Hypertension. 2003 Aug;42(2):206-12. Epub 2003 Jul 7.PMID: 12847113 [PubMed - indexed for MEDLINE]Related articlesFree article

Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

Zhou G, Li X, Hein DW, Xiang X, Marshall JP, Prabhu SD, Cai L.

J Am Coll Cardiol. 2008 Aug 19;52(8):655-66.PMID: 18702970 [PubMed - indexed for MEDLINE]Related articles

Diabetic Cardiomyopathy in OVE26 Mice Shows Mitochondrial ROS Production and Divergence Between In Vivo and In Vitro Contractility.

Song Y, Du Y, Prabhu SD, Epstein PN.

Rev Diabet Stud. 2007 Fall;4(3):159-68. Epub 2007 Nov 10.PMID: 18084673 [PubMed - in process]Related articlesFree article

Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.

Dong F, Li Q, Sreejayan N, Nunn JM, Ren J.

Diabetes. 2007 Sep;56(9):2201-12. Epub 2007 Jun 15.PMID: 17575086 [PubMed - indexed for MEDLINE]Related articlesFree article

Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.

Wold LE, Ceylan-Isik AF, Fang CX, Yang X, Li SY, Sreejayan N, Privratsky JR, Ren J.

Free Radic Biol Med. 2006 Apr 15;40(8):1419-29. Epub 2006 Jan 6.PMID: 16631532 [PubMed - indexed for MEDLINE]Related articles

Selenium prevents diabetes-induced alterations in [Zn2+]i and metallothionein level of rat heart via restoration of cell redox cycle.

Ayaz M, Turan B.

Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H1071-80. Epub 2005 Oct 7.PMID: 16214842 [PubMed - indexed for MEDLINE]Related articlesFree article

Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.

Fujii T, Onohara N, Maruyama Y, Tanabe S, Kobayashi H, Fukutomi M, Nagamatsu Y, Nishihara N, Inoue R, Sumimoto H, Shibasaki F, Nagao T, Nishida M, Kurose H.

J Biol Chem. 2005 Jun 17;280(24):23041-7. Epub 2005 Apr 12.PMID: 15826947 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species.

Lijnen P, Papparella I, Petrov V, Semplicini A, Fagard R.

J Hypertens. 2006 Apr;24(4):757-66.PMID: 16531806 [PubMed - indexed for MEDLINE]Related articles

Overexpression of metallothionein reduces diabetic cardiomyopathy.

Liang Q, Carlson EC, Donthi RV, Kralik PM, Shen X, Epstein PN.

Diabetes. 2002 Jan;51(1):174-81.PMID: 11756338 [PubMed - indexed for MEDLINE]Related articlesFree article

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes.

He X, Kan H, Cai L, Ma Q.

J Mol Cell Cardiol. 2009 Jan;46(1):47-58. Epub 2008 Nov 1.PMID: 19007787 [PubMed - indexed for MEDLINE]Related articles

Cardiomyocyte dysfunction in models of type 1 and type 2 diabetes.

Kralik PM, Ye G, Metreveli NS, Shem X, Epstein PN.

Cardiovasc Toxicol. 2005;5(3):285-92. Erratum in: Cardiovasc Toxicol. 2006;6(1):79. Kralik, Patricia M [added]; Donthi, Rajakumar V [removed]; Shem, Xia [added]. PMID: 16244373 [PubMed - indexed for MEDLINE]Related articles

Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius.

Wang G, Anrather J, Glass MJ, Tarsitano MJ, Zhou P, Frys KA, Pickel VM, Iadecola C.

Hypertension. 2006 Sep;48(3):482-9. Epub 2006 Aug 7.PMID: 16894058 [PubMed - indexed for MEDLINE]Related articlesFree article

G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.

Nishida M, Tanabe S, Maruyama Y, Mangmool S, Urayama K, Nagamatsu Y, Takagahara S, Turner JH, Kozasa T, Kobayashi H, Sato Y, Kawanishi T, Inoue R, Nagao T, Kurose H.

J Biol Chem. 2005 May 6;280(18):18434-41. Epub 2005 Mar 1.PMID: 15743761 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardiac overexpression of metallothionein attenuates chronic alcohol intake-induced cardiomyocyte contractile dysfunction.

Li Q, Ren J.

Cardiovasc Toxicol. 2006;6(3-4):173-82.PMID: 17347528 [PubMed - indexed for MEDLINE]Related articles

Activation of AP-1 through reactive oxygen species by angiotensin II in rat cardiomyocytes.

Wu S, Gao J, Ohlemeyer C, Roos D, Niessen H, Köttgen E, Gessner R.

Free Radic Biol Med. 2005 Dec 15;39(12):1601-10. Epub 2005 Aug 24.PMID: 16298685 [PubMed - indexed for MEDLINE]Related articles

Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt.

Fang CX, Doser TA, Yang X, Sreejayan N, Ren J.

Aging Cell. 2006 Apr;5(2):177-85.PMID: 16626396 [PubMed - indexed for MEDLINE]Related articles

Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity.

Dong F, Fang CX, Yang X, Zhang X, Lopez FL, Ren J.

Diabetologia. 2006 Jun;49(6):1421-33. Epub 2006 Apr 4.PMID: 16586065 [PubMed - indexed for MEDLINE]Related articles

Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.

Hsieh TJ, Fustier P, Wei CC, Zhang SL, Filep JG, Tang SS, Ingelfinger JR, Fantus IG, Hamet P, Chan JS.

J Endocrinol. 2004 Dec;183(3):535-50.PMID: 15590980 [PubMed - indexed for MEDLINE]Related articlesFree article