PubMed

Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat.

Stoffers DA, Desai BM, DeLeon DD, Simmons RA.

Diabetes. 2003 Mar;52(3):734-40.PMID: 12606515 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrauterine growth retardation leads to the development of type 2 diabetes in the rat.

Simmons RA, Templeton LJ, Gertz SJ.

Diabetes. 2001 Oct;50(10):2279-86.PMID: 11574409 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 normalizes islet vascularity in intrauterine growth restricted rats: potential role of VEGF.

Ham JN, Crutchlow MF, Desai BM, Simmons RA, Stoffers DA.

Pediatr Res. 2009 Jul;66(1):42-6.PMID: 19287346 [PubMed - indexed for MEDLINE]Related articles

Neonatal exendin-4 treatment reduces oxidative stress and prevents hepatic insulin resistance in intrauterine growth-retarded rats.

Raab EL, Vuguin PM, Stoffers DA, Simmons RA.

Am J Physiol Regul Integr Comp Physiol. 2009 Dec;297(6):R1785-94. Epub 2009 Oct 21.PMID: 19846744 [PubMed - in process]Related articles

Experimental intrauterine growth retardation in the rat causes a reduction of pancreatic B-cell mass, which persists into adulthood.

Styrud J, Eriksson UJ, Grill V, Swenne I.

Biol Neonate. 2005;88(2):122-8. Epub 2005 May 27.PMID: 15942163 [PubMed - indexed for MEDLINE]Related articles

Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells.

Movassat J, Beattie GM, Lopez AD, Hayek A.

J Clin Endocrinol Metab. 2002 Oct;87(10):4775-81.PMID: 12364473 [PubMed - indexed for MEDLINE]Related articlesFree article

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

Park JH, Stoffers DA, Nicholls RD, Simmons RA.

J Clin Invest. 2008 Jun;118(6):2316-24.PMID: 18464933 [PubMed - indexed for MEDLINE]Related articlesFree article

Modeling intrauterine growth retardation in rodents: Impact on pancreas development and glucose homeostasis.

Schwitzgebel VM, Somm E, Klee P.

Mol Cell Endocrinol. 2009 May 25;304(1-2):78-83. Epub 2009 Mar 9. Review.PMID: 19433251 [PubMed - indexed for MEDLINE]Related articles

Gestational diabetes leads to the development of diabetes in adulthood in the rat.

Boloker J, Gertz SJ, Simmons RA.

Diabetes. 2002 May;51(5):1499-506.PMID: 11978648 [PubMed - indexed for MEDLINE]Related articlesFree article

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Xu G, Stoffers DA, Habener JF, Bonner-Weir S.

Diabetes. 1999 Dec;48(12):2270-6.PMID: 10580413 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired oxidative phosphorylation in hepatic mitochondria in growth-retarded rats.

Peterside IE, Selak MA, Simmons RA.

Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1258-66.PMID: 14607783 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats.

Selak MA, Storey BT, Peterside I, Simmons RA.

Am J Physiol Endocrinol Metab. 2003 Jul;285(1):E130-7. Epub 2003 Mar 11.PMID: 12637257 [PubMed - indexed for MEDLINE]Related articlesFree article

PDX-1 expression is associated with islet proliferation in vitro and in vivo.

Feanny MA, Fagan SP, Ballian N, Liu SH, Li Z, Wang X, Fisher W, Brunicardi FC, Belaguli NS.

J Surg Res. 2008 Jan;144(1):8-16. Epub 2007 Jun 20.PMID: 17583748 [PubMed - indexed for MEDLINE]Related articles

Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.

Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, Shiota M, Charron MJ, Wright CV, Powers AC.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E707-14. Epub 2004 Nov 23.PMID: 15562255 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of metabolic programming in the pathogenesis of beta-cell failure in postnatal life.

Simmons RA.

Rev Endocr Metab Disord. 2007 Jun;8(2):95-104. Review.PMID: 17680370 [PubMed - indexed for MEDLINE]Related articles

Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat.

Lane RH, Flozak AS, Ogata ES, Bell GI, Simmons RA.

Pediatr Res. 1996 Mar;39(3):390-4.PMID: 8929856 [PubMed - indexed for MEDLINE]Related articles

Hepatic insulin resistance precedes the development of diabetes in a model of intrauterine growth retardation.

Vuguin P, Raab E, Liu B, Barzilai N, Simmons R.

Diabetes. 2004 Oct;53(10):2617-22.PMID: 15448092 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective morphogenesis and functional maturation in fetal islet-like cell clusters from OLETF rat, a model of NIDDM.

Zhu M, Mizuno A, Noma Y, Murakami T, Kuwajima M, Shima K, Lan MS.

Int J Exp Diabetes Res. 2001;1(4):289-98.PMID: 11467419 [PubMed - indexed for MEDLINE]Related articlesFree article

Uteroplacental insufficiency decreases small intestine growth and alters apoptotic homeostasis in term intrauterine growth retarded rats.

Baserga M, Bertolotto C, Maclennan NK, Hsu JL, Pham T, Laksana GS, Lane RH.

Early Hum Dev. 2004 Sep;79(2):93-105.PMID: 15324990 [PubMed - indexed for MEDLINE]Related articles

Altered pancreatic morphology in the offspring of pregnant rats given reduced dietary protein is time and gender specific.

Chamson-Reig A, Thyssen SM, Arany E, Hill DJ.

J Endocrinol. 2006 Oct;191(1):83-92.PMID: 17065391 [PubMed - indexed for MEDLINE]Related articlesFree article