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    Results: 1 to 20 of 400

    1.

    Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.

    Greening JE, Tree TI, Kotowicz KT, van Halteren AG, Roep BO, Klein NJ, Peakman M.

    Diabetes. 2003 Mar;52(3):717-25.PMID: 12606513 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes.

    Rharbaoui F, Mayer A, Granier C, Bouanani M, Thivolet C, Pau B, Orgiazzi J, Madec AM.

    Clin Exp Immunol. 1999 Jul;117(1):30-7.PMID: 10403912 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice.

    Liu J, Purdy LE, Rabinovitch S, Jevnikar AM, Elliott JF.

    Diabetes. 1999 Mar;48(3):469-77.PMID: 10078545 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

    Reijonen H, Daniels TL, Lernmark A, Nepom GT.

    Diabetes. 2000 Oct;49(10):1621-6.PMID: 11016444 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65.

    Tree TI, Duinkerken G, Willemen S, de Vries RR, Roep BO.

    Diabetes. 2004 Jul;53(7):1692-9.PMID: 15220192 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell assays in type 1 diabetes.

    Peakman M, Tree TI, Endl J, van Endert P, Atkinson MA, Roep BO; Second International Immunology of Diabetes Society Workshop for Standardization ot T-cell Assays in Type 1 Diabetes.

    Diabetes. 2001 Aug;50(8):1749-54.PMID: 11473034 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    HLA-DR binding analysis of peptides from islet antigens in IDDM.

    Geluk A, van Meijgaarden KE, Schloot NC, Drijfhout JW, Ottenhoff TH, Roep BO.

    Diabetes. 1998 Oct;47(10):1594-601.PMID: 9753297 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

    Nepom GT, Lippolis JD, White FM, Masewicz S, Marto JA, Herman A, Luckey CJ, Falk B, Shabanowitz J, Hunt DF, Engelhard VH, Nepom BS.

    Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1763-8.PMID: 11172025 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes.

    Harfouch-Hammoud E, Walk T, Otto H, Jung G, Bach JF, van Endert PM, Caillat-Zucman S.

    Diabetes. 1999 Oct;48(10):1937-47.PMID: 10512357 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    HLA-DR53 molecules restrict glutamic acid decarboxylase peptide presentation to T cells of a Type I diabetes patient: specification of the trimolecular HLA-peptide/T-cell receptor complex.

    Huck C, Endl J, Walk T, Noessner E, Jung G, Wank R, Schendel DJ.

    Diabetologia. 2001 Jan;44(1):70-80.PMID: 11206414 [PubMed - indexed for MEDLINE]Related articles

    11.

    Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice.

    Gebe JA, Unrath KA, Yue BB, Miyake T, Falk BA, Nepom GT.

    J Autoimmun. 2008 Jun;30(4):197-206. Epub 2007 Oct 18.PMID: 17949947 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4.

    Peakman M, Stevens EJ, Lohmann T, Narendran P, Dromey J, Alexander A, Tomlinson AJ, Trucco M, Gorga JC, Chicz RM.

    J Clin Invest. 1999 Nov;104(10):1449-57.PMID: 10562307 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

    Patel SD, Cope AP, Congia M, Chen TT, Kim E, Fugger L, Wherrett D, Sonderstrup-McDevitt G.

    Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8082-7.PMID: 9223318 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Activation of CD8+ T lymphocytes in insulin-dependent diabetes mellitus.

    Togun RA, Resetkova E, Kawai K, Enomoto T, Volpé R.

    Clin Immunol Immunopathol. 1997 Mar;82(3):243-9.PMID: 9073547 [PubMed - indexed for MEDLINE]Related articles

    15.

    Differential presentation of glutamic acid decarboxylase 65 (GAD65) T cell epitopes among HLA-DRB1*0401-positive individuals.

    Reijonen H, Elliott JF, van Endert P, Nepom G.

    J Immunol. 1999 Aug 1;163(3):1674-81.PMID: 10415074 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.

    Endl J, Otto H, Jung G, Dreisbusch B, Donie F, Stahl P, Elbracht R, Schmitz G, Meinl E, Hummel M, Ziegler AG, Wank R, Schendel DJ.

    J Clin Invest. 1997 May 15;99(10):2405-15.PMID: 9153283 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

    Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ.

    J Clin Invest. 1996 Dec 1;98(11):2597-603.PMID: 8958223 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice.

    Wen L, Wong FS, Burkly L, Altieri M, Mamalaki C, Kioussis D, Flavell RA, Sherwin RS.

    J Clin Invest. 1998 Sep 1;102(5):947-57. Erratum in: J Clin Invest 1998 Oct 1;102(7):following 1463. PMID: 9727063 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice.

    Abraham RS, Kudva YC, Wilson SB, Strominger JL, David CS.

    Diabetes. 2000 Apr;49(4):548-54.PMID: 10871191 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model.

    Abraham RS, Wen L, Marietta EV, David CS.

    J Immunol. 2001 Jan 15;166(2):1370-9.PMID: 11145722 [PubMed - indexed for MEDLINE]Related articlesFree article

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