PubMed

Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility.

Lan H, Rabaglia ME, Stoehr JP, Nadler ST, Schueler KL, Zou F, Yandell BS, Attie AD.

Diabetes. 2003 Mar;52(3):688-700.PMID: 12606510 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

Diabetes. 2006 Aug;55(8):2159-70.PMID: 16873678 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic background (C57BL/6J versus FVB/N) strongly influences the severity of diabetes and insulin resistance in ob/ob mice.

Haluzik M, Colombo C, Gavrilova O, Chua S, Wolf N, Chen M, Stannard B, Dietz KR, Le Roith D, Reitman ML.

Endocrinology. 2004 Jul;145(7):3258-64. Epub 2004 Apr 1.PMID: 15059949 [PubMed - indexed for MEDLINE]Related articlesFree article

The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.

Liang Y, She P, Wang X, Demarest K.

Metabolism. 2006 Oct;55(10):1411-9.PMID: 16979414 [PubMed - indexed for MEDLINE]Related articles

Genetic and genomic studies of the BTBR ob/ob mouse model of type 2 diabetes.

Clee SM, Nadler ST, Attie AD.

Am J Ther. 2005 Nov-Dec;12(6):491-8.PMID: 16280642 [PubMed - indexed for MEDLINE]Related articles

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity.

Rossmeisl M, Rim JS, Koza RA, Kozak LP.

Diabetes. 2003 Aug;52(8):1958-66.PMID: 12882911 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice.

Zhang B, Graziano MP, Doebber TW, Leibowitz MD, White-Carrington S, Szalkowski DM, Hey PJ, Wu M, Cullinan CA, Bailey P, Lollmann B, Frederich R, Flier JS, Strader CD, Smith RG.

J Biol Chem. 1996 Apr 19;271(16):9455-9.PMID: 8621615 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

Stoehr JP, Nadler ST, Schueler KL, Rabaglia ME, Yandell BS, Metz SA, Attie AD.

Diabetes. 2000 Nov;49(11):1946-54.PMID: 11078464 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic over-expression of peroxisome proliferator activated receptor gamma2 in the ob/ob mouse model of non-insulin dependent diabetes mellitus.

Rahimian R, Masih-Khan E, Lo M, van Breemen C, McManus BM, Dubé GP.

Mol Cell Biochem. 2001 Aug;224(1-2):29-37.PMID: 11693197 [PubMed - indexed for MEDLINE]Related articles

Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice.

Allen DL, Cleary AS, Speaker KJ, Lindsay SF, Uyenishi J, Reed JM, Madden MC, Mehan RS.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E918-27. Epub 2008 Mar 11.PMID: 18334608 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic expression of microsomal triglyceride transfer protein and in vivo secretion of triglyceride-rich lipoproteins are increased in obese diabetic mice.

Bartels ED, Lauritsen M, Nielsen LB.

Diabetes. 2002 Apr;51(4):1233-9.PMID: 11916950 [PubMed - indexed for MEDLINE]Related articlesFree article

Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: coordinated patterns of gene expression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis.

Colombo M, Kruhoeffer M, Gregersen S, Agger A, Jeppesen P, Oerntoft T, Hermansen K.

Metabolism. 2006 Jan;55(1):43-52.PMID: 16324918 [PubMed - indexed for MEDLINE]Related articles

Increased lipids in non-lipogenic tissues are indicators of the severity of type 2 diabetes in mice.

Campbell-Tofte J, Hansen HS, Mu H, Mølgaard P.

Prostaglandins Leukot Essent Fatty Acids. 2007 Jan;76(1):9-18. Epub 2006 Nov 13.PMID: 17098406 [PubMed - indexed for MEDLINE]Related articles

Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.

Suh YH, Kim Y, Bang JH, Choi KS, Lee JW, Kim WH, Oh TJ, An S, Jung MH.

J Mol Endocrinol. 2005 Apr;34(2):299-315.PMID: 15821098 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3.

Gao H, Bryzgalova G, Hedman E, Khan A, Efendic S, Gustafsson JA, Dahlman-Wright K.

Mol Endocrinol. 2006 Jun;20(6):1287-99. Epub 2006 Apr 20.PMID: 16627594 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes.

de Fourmestraux V, Neubauer H, Poussin C, Farmer P, Falquet L, Burcelin R, Delorenzi M, Thorens B.

J Biol Chem. 2004 Dec 3;279(49):50743-53. Epub 2004 Sep 17.PMID: 15377667 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucleotide microarray analysis.

Colombo M, Gregersen S, Kruhoeffer M, Agger A, Xiao J, Jeppesen PB, Orntoft T, Ploug T, Galbo H, Hermansen K.

Metabolism. 2005 Dec;54(12):1571-81.PMID: 16311088 [PubMed - indexed for MEDLINE]Related articles

Identification of novel genes differentially expressed in omental fat of obese subjects and obese type 2 diabetic patients.

Corominola H, Conner LJ, Beavers LS, Gadski RA, Johnson D, Caro JF, Rafaeloff-Phail R.

Diabetes. 2001 Dec;50(12):2822-30.PMID: 11723066 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptome of the subcutaneous adipose tissue in response to oral supplementation of type 2 Leprdb obese diabetic mice with niacin-bound chromium.

Rink C, Roy S, Khanna S, Rink T, Bagchi D, Sen CK.

Physiol Genomics. 2006 Nov 27;27(3):370-9. Epub 2006 Aug 29.PMID: 16940432 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytochemical analysis of pancreatic islet hypercytolipidemia following diabetes (db/db) and obese (ob/ob) mutation expression: influence of genomic background.

Garris DR, Garris BL.

Pathobiology. 2004;71(5):231-40.PMID: 15459481 [PubMed - indexed for MEDLINE]Related articles