PubMed

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

Daitoku H, Yamagata K, Matsuzaki H, Hatta M, Fukamizu A.

Diabetes. 2003 Mar;52(3):642-9.PMID: 12606503 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity.

Schmoll D, Walker KS, Alessi DR, Grempler R, Burchell A, Guo S, Walther R, Unterman TG.

J Biol Chem. 2000 Nov 17;275(46):36324-33.PMID: 10960473 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence.

Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T.

J Biol Chem. 1999 Jun 11;274(24):17184-92.PMID: 10358076 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription.

Tomizawa M, Kumar A, Perrot V, Nakae J, Accili D, Rechler MM.

J Biol Chem. 2000 Mar 10;275(10):7289-95. Erratum in: J Biol Chem 2000 Apr 14;275(15):11538. Kumaro A [corrected to Kumar A]. PMID: 10702299 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences.

Yeagley D, Guo S, Unterman T, Quinn PG.

J Biol Chem. 2001 Sep 7;276(36):33705-10. Epub 2001 Jul 9.PMID: 11445561 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular models for the analysis of signaling by protein kinase B and the forkhead transcription factor FKHR (Foxo1a).

Orth HM, Krüger KD, Schmoll D, Grempler R, Scherbaum WA, Joost HG, Bornstein SR, Barthel A.

Regul Pept. 2004 Sep 15;121(1-3):19-24.PMID: 15256269 [PubMed - indexed for MEDLINE]Related articles

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

Nakae J, Park BC, Accili D.

J Biol Chem. 1999 Jun 4;274(23):15982-5.PMID: 10347145 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.

Rena G, Guo S, Cichy SC, Unterman TG, Cohen P.

J Biol Chem. 1999 Jun 11;274(24):17179-83.PMID: 10358075 [PubMed - indexed for MEDLINE]Related articlesFree article

Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression.

Patel S, Lochhead PA, Rena G, Sutherland C.

Biochem J. 2001 Nov 1;359(Pt 3):611-9.PMID: 11672436 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1.

Nadal A, Marrero PF, Haro D.

Biochem J. 2002 Aug 15;366(Pt 1):289-97.PMID: 12027802 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins.

Richards JS, Sharma SC, Falender AE, Lo YH.

Mol Endocrinol. 2002 Mar;16(3):580-99.PMID: 11875118 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors.

Kwon HS, Huang B, Unterman TG, Harris RA.

Diabetes. 2004 Apr;53(4):899-910.PMID: 15047604 [PubMed - indexed for MEDLINE]Related articlesFree article

Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism.

Kortylewski M, Feld F, Krüger KD, Bahrenberg G, Roth RA, Joost HG, Heinrich PC, Behrmann I, Barthel A.

J Biol Chem. 2003 Feb 14;278(7):5242-9. Epub 2002 Nov 26.PMID: 12456685 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways.

Cahill CM, Tzivion G, Nasrin N, Ogg S, Dore J, Ruvkun G, Alexander-Bridges M.

J Biol Chem. 2001 Apr 20;276(16):13402-10. Epub 2000 Dec 20.PMID: 11124266 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription.

Schinner S, Barthel A, Dellas C, Grzeskowiak R, Sharma SK, Oetjen E, Blume R, Knepel W.

J Biol Chem. 2005 Feb 25;280(8):7369-76. Epub 2004 Dec 7.PMID: 15590659 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes.

Valverde AM, Arribas M, Mur C, Navarro P, Pons S, Cassard-Doulcier AM, Kahn CR, Benito M.

J Biol Chem. 2003 Mar 21;278(12):10221-31. Epub 2003 Jan 13.PMID: 12525499 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.

Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.

J Biol Chem. 2005 Jun 10;280(23):22297-307. Epub 2005 Apr 6.PMID: 15817464 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the versican promoter by the beta-catenin-T-cell factor complex in vascular smooth muscle cells.

Rahmani M, Read JT, Carthy JM, McDonald PC, Wong BW, Esfandiarei M, Si X, Luo Z, Luo H, Rennie PS, McManus BM.

J Biol Chem. 2005 Apr 1;280(13):13019-28. Epub 2005 Jan 24.PMID: 15668231 [PubMed - indexed for MEDLINE]Related articlesFree article

Construction and characterization of a conditionally active construct of the insulin-regulated forkhead transcription factor FKHR.

Barthel A, Orth HM, Krüger KD, Schmoll D, Joost HG.

Exp Clin Endocrinol Diabetes. 2002 Sep;110(6):304-9.PMID: 12373635 [PubMed - indexed for MEDLINE]Related articles

Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.

Jackson JG, Kreisberg JI, Koterba AP, Yee D, Brattain MG.

Oncogene. 2000 Sep 21;19(40):4574-81.PMID: 11030146 [PubMed - indexed for MEDLINE]Related articlesFree article