PubMed

Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus.

Pedotti R, Sanna M, Tsai M, DeVoss J, Steinman L, McDevitt H, Galli SJ.

BMC Immunol. 2003 Feb 22;4:2. Epub 2003 Feb 22.PMID: 12597780 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunization of non-obese diabetic (NOD) mice with glutamic acid decarboxylase-derived peptide 524-543 reduces cyclophosphamide-accelerated diabetes.

Saï P, Rivereau AS, Granier C, Haertlé T, Martignat L.

Clin Exp Immunol. 1996 Aug;105(2):330-7.PMID: 8706342 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of glutamic acid decarboxylase 65-specific Th2 cells and suppression of autoimmune diabetes at late stages of disease is epitope dependent.

Tisch R, Wang B, Serreze DV.

J Immunol. 1999 Aug 1;163(3):1178-87.PMID: 10415012 [PubMed - indexed for MEDLINE]Related articlesFree article

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.

Tian J, Atkinson MA, Clare-Salzler M, Herschenfeld A, Forsthuber T, Lehmann PV, Kaufman DL.

J Exp Med. 1996 Apr 1;183(4):1561-7.PMID: 8666914 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity.

Quinn A, McInerney MF, Sercarz EE.

J Immunol. 2001 Aug 1;167(3):1748-57.PMID: 11466400 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulatory Th2-type T cell lines against insulin and GAD peptides derived from orally- and nasally-treated NOD mice suppress diabetes.

Maron R, Melican NS, Weiner HL.

J Autoimmun. 1999 Jun;12(4):251-8.PMID: 10330296 [PubMed - indexed for MEDLINE]Related articles

Active tolerance induction and prevention of autoimmune diabetes by immunogene therapy using recombinant adenoassociated virus expressing glutamic acid decarboxylase 65 peptide GAD(500-585).

Han G, Li Y, Wang J, Wang R, Chen G, Song L, Xu R, Yu M, Wu X, Qian J, Shen B.

J Immunol. 2005 Apr 15;174(8):4516-24.PMID: 15814672 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic alteration of insulin-dependent diabetes mellitus progression by T cell tolerance to glutamic acid decarboxylase 65 peptides in vitro and in vivo.

Wilson SS, White TC, DeLuca D.

J Immunol. 2001 Jul 1;167(1):569-77.PMID: 11418696 [PubMed - indexed for MEDLINE]Related articlesFree article

T cells with multiple fine specificities are used by non-obese diabetic (NOD) mice in the response to GAD(524-543).

Quinn A, Sercarz EE.

J Autoimmun. 1996 Jun;9(3):365-70.PMID: 8816972 [PubMed - indexed for MEDLINE]Related articles

Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells.

Kim SK, Tarbell KV, Sanna M, Vadeboncoeur M, Warganich T, Lee M, Davis M, McDevitt HO.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14204-9. Epub 2004 Sep 20.PMID: 15381770 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous immune response to glutamic acid decarboxylase (GAD67) in NOD mice is modulated by adjuvant immunotherapy.

Qin HY, Elliott JF, Lakey JR, Rajotte RV, Singh B.

J Autoimmun. 1998 Dec;11(6):591-601.PMID: 9878081 [PubMed - indexed for MEDLINE]Related articles

Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase.

Jun HS, Chung YH, Han J, Kim A, Yoo SS, Sherwin RS, Yoon JW.

Diabetologia. 2002 May;45(5):668-76. Epub 2002 Apr 4.PMID: 12107747 [PubMed - indexed for MEDLINE]Related articles

B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice.

Falcone M, Lee J, Patstone G, Yeung B, Sarvetnick N.

J Immunol. 1998 Aug 1;161(3):1163-8.PMID: 9686575 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral T cell clones from NOD mice specific for GAD65 peptides: lack of islet responsiveness or diabetogenicity.

Schloot NC, Daniel D, Norbury-Glaser M, Wegmann DR.

J Autoimmun. 1996 Jun;9(3):357-63.PMID: 8816971 [PubMed - indexed for MEDLINE]Related articles

Anti-GAD monoclonal antibody delays the onset of diabetes mellitus in NOD mice.

Menard V, Jacobs H, Jun HS, Yoon JW, Kim SW.

Pharm Res. 1999 Jul;16(7):1059-66.PMID: 10450931 [PubMed - indexed for MEDLINE]Related articles

Responses of NOD congenic mice to a glutamic acid decarboxylase-derived peptide.

Chen SL, Whiteley PJ, Freed DC, Rothbard JB, Peterson LB, Wicker LS.

J Autoimmun. 1994 Oct;7(5):635-41.PMID: 7840855 [PubMed - indexed for MEDLINE]Related articles

Regulatory and effector CD4 T cells in nonobese diabetic mice recognize overlapping determinants on glutamic acid decarboxylase and use distinct V beta genes.

Quinn A, McInerney B, Reich EP, Kim O, Jensen KP, Sercarz EE.

J Immunol. 2001 Mar 1;166(5):2982-91.PMID: 11207247 [PubMed - indexed for MEDLINE]Related articlesFree article

DNA vaccination encoding glutamic acid decarboxylase can enhance insulitis and diabetes in correlation with a specific Th2/3 CD4 T cell response in non-obese diabetic mice.

Gauvrit A, Debailleul M, Vu AT, Sai P, Bach JM.

Clin Exp Immunol. 2004 Aug;137(2):253-62.PMID: 15270841 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice.

Weaver DJ Jr, Liu B, Tisch R.

J Immunol. 2001 Jul 1;167(1):586-92.PMID: 11418698 [PubMed - indexed for MEDLINE]Related articlesFree article

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes.

Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GS, Robinson P, Atkinson MA, Sercarz EE, Tobin AJ, Lehmann PV.

Nature. 1993 Nov 4;366(6450):69-72.PMID: 7694152 [PubMed - indexed for MEDLINE]Related articles