PubMed

The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia.

Kubaszek A, Pihlajamäki J, Karhapää P, Vauhkonen I, Laakso M.

Diabetes Care. 2003 Feb;26(2):464-7.PMID: 12547881 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic polymorphism PC-1 K121Q and ethnic susceptibility to insulin resistance.

Abate N, Carulli L, Cabo-Chan A Jr, Chandalia M, Snell PG, Grundy SM.

J Clin Endocrinol Metab. 2003 Dec;88(12):5927-34.PMID: 14671192 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms.

Baratta R, Di Paola R, Spampinato D, Fini G, Marucci A, Coco A, Vigneri R, Frittitta L, Trischitta V.

J Mol Med. 2003 Nov;81(11):718-23. Epub 2003 Oct 22.PMID: 14574455 [PubMed - indexed for MEDLINE]Related articles

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance.

Pizzuti A, Frittitta L, Argiolas A, Baratta R, Goldfine ID, Bozzali M, Ercolino T, Scarlato G, Iacoviello L, Vigneri R, Tassi V, Trischitta V.

Diabetes. 1999 Sep;48(9):1881-4.PMID: 10480624 [PubMed - indexed for MEDLINE]Related articlesFree article

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

Rasmussen SK, Urhammer SA, Pizzuti A, Echwald SM, Ekstrøm CT, Hansen L, Hansen T, Borch-Johnsen K, Frittitta L, Trischitta V, Pedersen O.

Diabetes. 2000 Sep;49(9):1608-11.PMID: 10969849 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation.

Perticone F, Maio R, Di Paola R, Sciacqua A, Marucci A, De Cosmo S, Perticone M, Sesti G, Trischitta V.

Nutr Metab Cardiovasc Dis. 2007 Mar;17(3):181-7. Epub 2006 Mar 20.PMID: 17367703 [PubMed - indexed for MEDLINE]Related articles

Obesity risk associated with the K121Q polymorphism of the glycoprotein PC-1 gene.

Wan C, Zhang T, Wang B, Han Y, Zhang C, Zhang Y, Gong H, Jin F, Wang L.

Diabetes Obes Metab. 2006 Nov;8(6):703-8.PMID: 17026496 [PubMed - indexed for MEDLINE]Related articles

K121Q PC-1 gene polymorphism is not associated with insulin resistance in a Spanish population.

González-Sánchez JL, Martínez-Larrad MT, Fernández-Pérez C, Kubaszek A, Laakso M, Serrano-Ríos M.

Obes Res. 2003 May;11(5):603-5.PMID: 12740448 [PubMed - indexed for MEDLINE]Related articles

Association of ENPP1 (PC-1) K121Q polymorphism with obesity-related parameters in subjects with metabolic syndrome.

González-Sánchez JL, Zabena C, Martínez-Larrad MT, Martínez-Calatrava MJ, Pérez-Barba M, Serrano-Ríos M.

Clin Endocrinol (Oxf). 2008 May;68(5):724-9. Epub 2007 Nov 6.PMID: 17986276 [PubMed - indexed for MEDLINE]Related articles

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.

Grarup N, Urhammer SA, Ek J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2006 Sep;49(9):2097-104. Epub 2006 Jul 25.PMID: 16865358 [PubMed - indexed for MEDLINE]Related articles

The association of PC-1 (ENPP1) K121Q polymorphism with metabolic syndrome in patients with coronary heart disease.

Tasic I, Milojkovic M, Sunder-Plassmann R, Lazarevic G, Tasic NM, Stefanovic V.

Clin Chim Acta. 2007 Feb;377(1-2):237-42. Epub 2006 Oct 11.PMID: 17129580 [PubMed - indexed for MEDLINE]Related articles

The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance.

Frittitta L, Baratta R, Spampinato D, Di Paola R, Pizzuti A, Vigneri R, Trischitta V.

J Clin Endocrinol Metab. 2001 Dec;86(12):5888-91.PMID: 11739459 [PubMed - indexed for MEDLINE]Related articlesFree article

Population-specific alleles: the polymorphism (K121Q) of the human glycoprotein PC-1 gene is strongly associated with race but not with insulin resistance in black and white children.

Morrison JA, Gruppo R, Glueck CJ, Stroop D, Fontaine RN, Wang P, Smith KL.

Metabolism. 2004 Apr;53(4):465-8.PMID: 15045693 [PubMed - indexed for MEDLINE]Related articles

Association of a genetic polymorphism in ectonucleotide pyrophosphatase/phosphodiesterase 1 with hepatitis C virus infection and hepatitis C virus core antigen levels in subjects in a hyperendemic area of Japan.

Takahama Y, Uto H, Kanmura S, Oketani M, Ido A, Kusumoto K, Hasuike S, Nagata K, Hayashi K, Stuver S, Okayama A, Tsubouchi H.

J Gastroenterol. 2008;43(12):942-50. Epub 2008 Dec 24.PMID: 19107338 [PubMed - indexed for MEDLINE]Related articles

Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects.

Bonnet F, Patel S, Laville M, Balkau B, Favuzzi A, Monti LD, Lalic N, Walker M; European Group for the Study of Insulin Resistance Relationship Between Insulin Sensitivity and Cardiovascular Disease Risk Study Group.

Diabetes Care. 2008 Apr;31(4):789-94. Epub 2008 Jan 30.PMID: 18235053 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

Gu HF, Almgren P, Lindholm E, Frittitta L, Pizzuti A, Trischitta V, Groop LC.

Diabetes. 2000 Sep;49(9):1601-3.PMID: 10969847 [PubMed - indexed for MEDLINE]Related articlesFree article

The association of the K121Q polymorphism of the plasma cell glycoprotein-1 gene with type 2 diabetes and hypertension depends on size at birth.

Kubaszek A, Markkanen A, Eriksson JG, Forsen T, Osmond C, Barker DJ, Laakso M.

J Clin Endocrinol Metab. 2004 May;89(5):2044-7.PMID: 15126519 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of the rs997509 polymorphism on the association between ectonucleotide pyrophosphatase phosphodiesterase 1 and metabolic syndrome and impaired glucose tolerance in childhood obesity.

Santoro N, Cirillo G, Lepore MG, Palma A, Amato A, Savarese P, Marzuillo P, Grandone A, Perrone L, Del Giudice EM.

J Clin Endocrinol Metab. 2009 Jan;94(1):300-5. Epub 2008 Oct 21.PMID: 18940878 [PubMed - indexed for MEDLINE]Related articles

Glucose-mediated glucose disposal in insulin-resistant normoglycemic relatives of type 2 diabetic patients.

Henriksen JE, Levin K, Thye-Rønn P, Alford F, Hother-Nielsen O, Holst JJ, Beck-Nielsen H.

Diabetes. 2000 Jul;49(7):1209-18.PMID: 10909980 [PubMed - indexed for MEDLINE]Related articlesFree article

[TNF-alpha PC-1 gene polymorphisms and pre-diabetes quantitative features in the Polish population]

Wanic K, Małecki M, Klupa T, Witek P, Kozek E, Sieradzki J.

Przegl Lek. 2002;59(11):888-91. Polish. PMID: 12715715 [PubMed - indexed for MEDLINE]Related articles