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    Results: 1 to 20 of 388

    1.

    Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension.

    Kelly DJ, Zhang Y, Hepper C, Gow RM, Jaworski K, Kemp BE, Wilkinson-Berka JL, Gilbert RE.

    Diabetes. 2003 Feb;52(2):512-8.PMID: 12540629 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Effects on protein kinase C-beta inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy.

    Kelly DJ, Buck D, Cox AJ, Zhang Y, Gilbert RE.

    Am J Physiol Renal Physiol. 2007 Aug;293(2):F565-74. Epub 2007 May 23.PMID: 17522264 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.

    Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R.

    FASEB J. 2000 Mar;14(3):439-47.PMID: 10698958 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    A novel potential therapy for diabetic nephropathy and vascular complications: protein kinase C beta inhibition.

    Tuttle KR, Anderson PW.

    Am J Kidney Dis. 2003 Sep;42(3):456-65. Review.PMID: 12955673 [PubMed - indexed for MEDLINE]Related articles

    5.

    Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy.

    Mifsud S, Kelly DJ, Qi W, Zhang Y, Pollock CA, Wilkinson-Berka JL, Gilbert RE.

    Nephron Physiol. 2003;95(4):p83-91.PMID: 14694265 [PubMed - indexed for MEDLINE]Related articles

    6.

    Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats.

    Koya D, Jirousek MR, Lin YW, Ishii H, Kuboki K, King GL.

    J Clin Invest. 1997 Jul 1;100(1):115-26.PMID: 9202063 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Protein kinase C beta inhibitor LY333531 attenuates intercellular adhesion molecule-1 and monocyte chemotactic protein-1 expression in the kidney in diabetic rats.

    Wu Y, Wu G, Qi X, Lin H, Qian H, Shen J, Lin S.

    J Pharmacol Sci. 2006 Aug;101(4):335-43. Epub 2006 Aug 5.PMID: 16891764 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy.

    Kelly DJ, Chanty A, Gow RM, Zhang Y, Gilbert RE.

    J Am Soc Nephrol. 2005 Jun;16(6):1654-60. Epub 2005 Apr 20.PMID: 15843473 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease.

    Kelly DJ, Edgley AJ, Zhang Y, Thai K, Tan SM, Cox AJ, Advani A, Connelly KA, Whiteside CI, Gilbert RE.

    Nephrol Dial Transplant. 2009 Jun;24(6):1782-90. Epub 2009 Jan 20.PMID: 19155535 [PubMed - indexed for MEDLINE]Related articles

    10.

    Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice.

    Menne J, Park JK, Boehne M, Elger M, Lindschau C, Kirsch T, Meier M, Gueler F, Fiebeler A, Bahlmann FH, Leitges M, Haller H.

    Diabetes. 2004 Aug;53(8):2101-9.PMID: 15277392 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Angiotensin converting enzyme inhibitor suppresses glomerular transforming growth factor beta receptor expression in experimental diabetes in rats.

    Hill C, Logan A, Smith C, Grønbaek H, Flyvbjerg A.

    Diabetologia. 2001 Apr;44(4):495-500.PMID: 11357481 [PubMed - indexed for MEDLINE]Related articles

    12.

    Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.

    Bursell SE, Takagi C, Clermont AC, Takagi H, Mori F, Ishii H, King GL.

    Invest Ophthalmol Vis Sci. 1997 Dec;38(13):2711-20.PMID: 9418723 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Spontaneous remission of diabetes arrests progression of nephropathy in streptozotocin-treated spontaneously hypertensive rats.

    Iwase M, Wakisaka M, Sato Y, Yoshinari M, Nunoi K, Ochi N, Fujishima M.

    Diabetes Res Clin Pract. 1994 Jan;22(2-3):129-37.PMID: 8200294 [PubMed - indexed for MEDLINE]Related articles

    14.

    The effects of perindopril and triple therapy in a normotensive model of diabetic nephropathy.

    O'Brien RC, Cooper ME, Jerums G, Doyle AE.

    Diabetes. 1993 Apr;42(4):604-9.PMID: 8454112 [PubMed - indexed for MEDLINE]Related articles

    15.

    A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats.

    Nakamura J, Kato K, Hamada Y, Nakayama M, Chaya S, Nakashima E, Naruse K, Kasuya Y, Mizubayashi R, Miwa K, Yasuda Y, Kamiya H, Ienaga K, Sakakibara F, Koh N, Hotta N.

    Diabetes. 1999 Oct;48(10):2090-5.PMID: 10512378 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model.

    Meier M, Park JK, Overheu D, Kirsch T, Lindschau C, Gueler F, Leitges M, Menne J, Haller H.

    Diabetes. 2007 Feb;56(2):346-54.PMID: 17259378 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Transforming growth factor-beta2 antibody attenuates fibrosis in the experimental diabetic rat kidney.

    Hill C, Flyvbjerg A, Rasch R, Bak M, Logan A.

    J Endocrinol. 2001 Sep;170(3):647-51.PMID: 11524245 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    d-alpha-tocopherol treatment prevents glomerular dysfunctions in diabetic rats through inhibition of protein kinase C-diacylglycerol pathway.

    Koya D, Haneda M, Kikkawa R, King GL.

    Biofactors. 1998;7(1-2):69-76.PMID: 9523030 [PubMed - indexed for MEDLINE]Related articles

    19.

    Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy.

    Connelly KA, Kelly DJ, Zhang Y, Prior DL, Advani A, Cox AJ, Thai K, Krum H, Gilbert RE.

    Circ Heart Fail. 2009 Mar;2(2):129-37. Epub 2009 Feb 10.PMID: 19808328 [PubMed - indexed for MEDLINE]Related articles

    20.

    Effects of diabetes and hypertension on glomerular transforming growth factor-beta receptor expression.

    Kang MJ, Ingram A, Ly H, Thai K, Scholey JW.

    Kidney Int. 2000 Oct;58(4):1677-85.PMID: 11012901 [PubMed - indexed for MEDLINE]Related articlesFree article

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