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Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice.

Nonogaki K, Abdallah L, Goulding EH, Bonasera SJ, Tecott LH.

Diabetes. 2003 Feb;52(2):315-20.PMID: 12540602 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice.

Nonogaki K, Memon RA, Grunfeld C, Feingold KR, Tecott LH.

Biochem Biophys Res Commun. 2002 Jul 12;295(2):249-54.PMID: 12150939 [PubMed - indexed for MEDLINE]Related articles

Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors.

Lam DD, Przydzial MJ, Ridley SH, Yeo GS, Rochford JJ, O'Rahilly S, Heisler LK.

Endocrinology. 2008 Mar;149(3):1323-8. Epub 2007 Nov 26.PMID: 18039773 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass.

Kawahara Y, Grimberg A, Teegarden S, Mombereau C, Liu S, Bale TL, Blendy JA, Nishikura K.

J Neurosci. 2008 Nov 26;28(48):12834-44.PMID: 19036977 [PubMed - indexed for MEDLINE]Related articlesFree article

Repeated stress in young and old 5-HT(2C) receptor knockout mice.

Chou-Green JM, Holscher TD, Dallman MF, Akana SF.

Physiol Behav. 2003 Jul;79(2):217-26.PMID: 12834793 [PubMed - indexed for MEDLINE]Related articles

A paradoxical locomotor response in serotonin 5-HT(2C) receptor mutant mice.

Heisler LK, Tecott LH.

J Neurosci. 2000 Apr 15;20(8):RC71.PMID: 10751458 [PubMed - indexed for MEDLINE]Related articles

Knockout Corner: Neurobehavioural consequences of a serotonin 5-HT(2C) receptor gene mutation.

Heisler LK, Tecott LH.

Int J Neuropsychopharmacol. 1999 Mar;2(1):67-69.PMID: 11281972 [PubMed - as supplied by publisher]Related articles

Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene.

Nonogaki K, Strack AM, Dallman MF, Tecott LH.

Nat Med. 1998 Oct;4(10):1152-6.PMID: 9771748 [PubMed - indexed for MEDLINE]Related articles

mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes.

Dalton GL, Lee MD, Kennett GA, Dourish CT, Clifton PG.

Neuropharmacology. 2004 Apr;46(5):663-71.PMID: 14996544 [PubMed - indexed for MEDLINE]Related articles

Serotonin 5- HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors.

López-Giménez JF, Tecott LH, Palacios JM, Mengod G, Vilaró MT.

J Neurosci Res. 2002 Jan 1;67(1):69-85.PMID: 11754082 [PubMed - indexed for MEDLINE]Related articles

Hyperphagia alters expression of hypothalamic 5-HT2C and 5-HT1B receptor genes and plasma des-acyl ghrelin levels in Ay mice.

Nonogaki K, Nozue K, Oka Y.

Endocrinology. 2006 Dec;147(12):5893-900. Epub 2006 Sep 14.PMID: 16973729 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential expression of 5-HT(2A) and 5-HT(2C) receptor mRNAs in mice prone, or resistant, to chronic high-fat diet-induced obesity.

Huang XF, Han M, Storlien LH.

Brain Res Mol Brain Res. 2004 Aug 23;127(1-2):39-47.PMID: 15306119 [PubMed - indexed for MEDLINE]Related articles

Epilepsy and obesity in serotonin 5-HT2C receptor mutant mice.

Heisler LK, Chu HM, Tecott LH.

Ann N Y Acad Sci. 1998 Dec 15;861:74-8. Review.PMID: 9928241 [PubMed - indexed for MEDLINE]Related articles

5-HT2A/2C receptor and 5-HT transporter densities in mice prone or resistant to chronic high-fat diet-induced obesity: a quantitative autoradiography study.

Huang XF, Huang X, Han M, Chen F, Storlien L, Lawrence AJ.

Brain Res. 2004 Aug 27;1018(2):227-35.PMID: 15276882 [PubMed - indexed for MEDLINE]Related articles

Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females.

Qiu J, Xue C, Bosch MA, Murphy JG, Fan W, Rønnekleiv OK, Kelly MJ.

Mol Pharmacol. 2007 Oct;72(4):885-96. Epub 2007 Jul 10.PMID: 17622577 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.

Clerc P, Coll Constans MG, Lulka H, Broussaud S, Guigné C, Leung-Theung-Long S, Perrin C, Knauf C, Carpéné C, Pénicaud L, Seva C, Burcelin R, Valet P, Fourmy D, Dufresne M.

Endocrinology. 2007 Mar;148(3):1039-49. Epub 2006 Nov 22.PMID: 17122076 [PubMed - indexed for MEDLINE]Related articlesFree article

5-HT2C receptor agonists as potential drugs for the treatment of obesity.

Bickerdike MJ.

Curr Top Med Chem. 2003;3(8):885-97. Review.PMID: 12678838 [PubMed - indexed for MEDLINE]Related articles

Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure.

Pfluger PT, Kirchner H, Günnel S, Schrott B, Perez-Tilve D, Fu S, Benoit SC, Horvath T, Joost HG, Wortley KE, Sleeman MW, Tschöp MH.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G610-8. Epub 2007 Nov 29.PMID: 18048479 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses.

Backstrom JR, Price RD, Reasoner DT, Sanders-Bush E.

J Biol Chem. 2000 Aug 4;275(31):23620-6.PMID: 10816555 [PubMed - indexed for MEDLINE]Related articlesFree article

Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways.

Zhou L, Sutton GM, Rochford JJ, Semple RK, Lam DD, Oksanen LJ, Thornton-Jones ZD, Clifton PG, Yueh CY, Evans ML, McCrimmon RJ, Elmquist JK, Butler AA, Heisler LK.

Cell Metab. 2007 Nov;6(5):398-405.PMID: 17983585 [PubMed - indexed for MEDLINE]Related articlesFree article