PubMed

Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy.

Simha V, Szczepaniak LS, Wagner AJ, DePaoli AM, Garg A.

Diabetes Care. 2003 Jan;26(1):30-5.PMID: 12502655 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy.

Ebihara K, Kusakabe T, Hirata M, Masuzaki H, Miyanaga F, Kobayashi N, Tanaka T, Chusho H, Miyazawa T, Hayashi T, Hosoda K, Ogawa Y, DePaoli AM, Fukushima M, Nakao K.

J Clin Endocrinol Metab. 2007 Feb;92(2):532-41. Epub 2006 Nov 21.PMID: 17118991 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation.

Perseghin G, Lattuada G, De Cobelli F, Esposito A, Belloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L.

J Clin Endocrinol Metab. 2007 Dec;92(12):4883-8. Epub 2007 Nov 6.PMID: 17986645 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased intramyocellular lipid concentration identifies impaired glucose metabolism in women with previous gestational diabetes.

Kautzky-Willer A, Krssak M, Winzer C, Pacini G, Tura A, Farhan S, Wagner O, Brabant G, Horn R, Stingl H, Schneider B, Waldhäusl W, Roden M.

Diabetes. 2003 Feb;52(2):244-51.PMID: 12540593 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.

Park JY, Chong AY, Cochran EK, Kleiner DE, Haller MJ, Schatz DA, Gorden P.

J Clin Endocrinol Metab. 2008 Jan;93(1):26-31. Epub 2007 Oct 16.PMID: 17940115 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies.

Hwang JH, Stein DT, Barzilai N, Cui MH, Tonelli J, Kishore P, Hawkins M.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1663-9. Epub 2007 Oct 2.PMID: 17911339 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans.

Bachmann OP, Dahl DB, Brechtel K, Machann J, Haap M, Maier T, Loviscach M, Stumvoll M, Claussen CD, Schick F, Häring HU, Jacob S.

Diabetes. 2001 Nov;50(11):2579-84.PMID: 11679437 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes.

Perseghin G, Lattuada G, Danna M, Sereni LP, Maffi P, De Cobelli F, Battezzati A, Secchi A, Del Maschio A, Luzi L.

Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1174-81. Epub 2003 Aug 21.PMID: 12933352 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin-replacement therapy for lipodystrophy.

Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A.

N Engl J Med. 2002 Feb 21;346(8):570-8.PMID: 11856796 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes.

Perseghin G, Lattuada G, De Cobelli F, Esposito A, Costantino F, Canu T, Scifo P, De Taddeo F, Maffi P, Secchi A, Del Maschio A, Luzi L.

Diabetologia. 2005 Dec;48(12):2615-21. Epub 2005 Nov 1.PMID: 16261312 [PubMed - indexed for MEDLINE]Related articles

Altered myocellular and abdominal fat partitioning predict disturbance in insulin action in HIV protease inhibitor-related lipodystrophy.

Gan SK, Samaras K, Thompson CH, Kraegen EW, Carr A, Cooper DA, Chisholm DJ.

Diabetes. 2002 Nov;51(11):3163-9.PMID: 12401706 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects.

Sato F, Tamura Y, Watada H, Kumashiro N, Igarashi Y, Uchino H, Maehara T, Kyogoku S, Sunayama S, Sato H, Hirose T, Tanaka Y, Kawamori R.

J Clin Endocrinol Metab. 2007 Aug;92(8):3326-9. Epub 2007 May 22.PMID: 17519317 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects.

Schrauwen-Hinderling VB, Kooi ME, Hesselink MK, Jeneson JA, Backes WH, van Echteld CJ, van Engelshoven JM, Mensink M, Schrauwen P.

Diabetologia. 2007 Jan;50(1):113-20. Epub 2006 Nov 9.PMID: 17093944 [PubMed - indexed for MEDLINE]Related articles

Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients.

Tamura Y, Tanaka Y, Sato F, Choi JB, Watada H, Niwa M, Kinoshita J, Ooka A, Kumashiro N, Igarashi Y, Kyogoku S, Maehara T, Kawasumi M, Hirose T, Kawamori R.

J Clin Endocrinol Metab. 2005 Jun;90(6):3191-6. Epub 2005 Mar 15.PMID: 15769987 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle.

Anderwald C, Bernroider E, Krssak M, Stingl H, Brehm A, Bischof MG, Nowotny P, Roden M, Waldhäusl W.

Diabetes. 2002 Oct;51(10):3025-32.PMID: 12351443 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

Jacob S, Machann J, Rett K, Brechtel K, Volk A, Renn W, Maerker E, Matthaei S, Schick F, Claussen CD, Häring HU.

Diabetes. 1999 May;48(5):1113-9.PMID: 10331418 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidation.

Perseghin G, Scifo P, Danna M, Battezzati A, Benedini S, Meneghini E, Del Maschio A, Luzi L.

Am J Physiol Endocrinol Metab. 2002 Sep;283(3):E556-64.PMID: 12169449 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes.

Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI.

N Engl J Med. 2004 Feb 12;350(7):664-71.PMID: 14960743 [PubMed - indexed for MEDLINE]Related articlesFree article

Proton magnetic resonance spectroscopy study of soleus muscle in non-obese healthy and Type 2 diabetic Asian Northern Indian males: high intramyocellular lipid content correlates with excess body fat and abdominal obesity.

Misra A, Sinha S, Kumar M, Jagannathan NR, Pandey RM.

Diabet Med. 2003 May;20(5):361-7.PMID: 12752484 [PubMed - indexed for MEDLINE]Related articles

Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy.

Park JY, Javor ED, Cochran EK, DePaoli AM, Gorden P.

Metabolism. 2007 Apr;56(4):508-16.PMID: 17379009 [PubMed - indexed for MEDLINE]Related articlesFree article