PubMed

The insulin gene variable number tandem repeat class I/III polymorphism is in linkage disequilibrium with birth weight but not Type 2 diabetes in the Pima population.

Lindsay RS, Hanson RL, Wiedrich C, Knowler WC, Bennett PH, Baier LJ.

Diabetes. 2003 Jan;52(1):187-93.PMID: 12502511 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of support for a role of the insulin gene variable number of tandem repeats minisatellite (INS-VNTR) locus in fetal growth or type 2 diabetes-related intermediate traits in United Kingdom populations.

Mitchell SM, Hattersley AT, Knight B, Turner T, Metcalf BS, Voss LD, Davies D, McCarthy A, Wilkin TJ, Smith GD, Ben-Shlomo Y, Frayling TM.

J Clin Endocrinol Metab. 2004 Jan;89(1):310-7.PMID: 14715866 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles.

Huxtable SJ, Saker PJ, Haddad L, Walker M, Frayling TM, Levy JC, Hitman GA, O'Rahilly S, Hattersley AT, McCarthy MI.

Diabetes. 2000 Jan;49(1):126-30.PMID: 10615960 [PubMed - indexed for MEDLINE]Related articlesFree article

The insulin gene variable number tandem repeat and risk of type 2 diabetes in a population-based sample of families and unrelated men and women.

Meigs JB, Dupuis J, Herbert AG, Liu C, Wilson PW, Cupples LA.

J Clin Endocrinol Metab. 2005 Feb;90(2):1137-43. Epub 2004 Nov 23.PMID: 15562019 [PubMed - indexed for MEDLINE]Related articlesFree article

Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release.

Hansen SK, Gjesing AP, Rasmussen SK, Glümer C, Urhammer SA, Andersen G, Rose CS, Drivsholm T, Torekov SK, Jensen DP, Ekstrøm CT, Borch-Johnsen K, Jørgensen T, McCarthy MI, Hansen T, Pedersen O.

Diabetologia. 2004 Jun;47(6):1079-87. Epub 2004 May 29.PMID: 15170498 [PubMed - indexed for MEDLINE]Related articles

Variation at the insulin gene VNTR (variable number tandem repeat) polymorphism and early growth: studies in a large Finnish birth cohort.

Bennett AJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Taponen S, Hartikainen AL, King VJ, Elliott P, Järvelin MR, McCarthy MI.

Diabetes. 2004 Aug;53(8):2126-31.PMID: 15277396 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneity of class I INS VNTR allele association with insulin secretion in obese children.

Le Fur S, Auffray C, Letourneur F, Cruaud C, Le Stunff C, Bougnères P.

Physiol Genomics. 2006 May 16;25(3):480-4. Epub 2006 Mar 28.PMID: 16569775 [PubMed - indexed for MEDLINE]Related articlesFree article

The relation between size at birth and risk of type 1 diabetes is not influenced by adjustment for the insulin gene (-23HphI) polymorphism or HLA-DQ genotype.

Stene LC, Thorsby PM, Berg JP, Rønningen KS, Undlien DE, Joner G; Norwegian Childhood Diabetes Study Group.

Diabetologia. 2006 Sep;49(9):2068-73. Epub 2006 May 12.PMID: 16691379 [PubMed - indexed for MEDLINE]Related articles

CTLA4 gene polymorphism contributes to the mode of onset of diabetes with antiglutamic acid decarboxylase antibody in Japanese patients: genetic analysis of diabetic patients with antiglutamic acid decarboxylase antibody.

Abe T, Yamaguchi Y, Takino H, Fujita N, Yamauchi-Degawa M, Ozaki M, Yamakawa K, Sera Y, Sakamaki H, Uotani S, Kawasaki E, Awata T, Yamasaki H, Eguchi K.

Diabet Med. 2001 Sep;18(9):726-31.PMID: 11606170 [PubMed - indexed for MEDLINE]Related articles

Analysis of linkage disequilibrium between polymorphisms in the KCNJ9 gene with type 2 diabetes mellitus in Pima Indians.

Wolford JK, Hanson RL, Kobes S, Bogardus C, Prochazka M.

Mol Genet Metab. 2001 May;73(1):97-103.PMID: 11350189 [PubMed - indexed for MEDLINE]Related articles

Associations of IGF2 ApaI RFLP and INS VNTR class I allele size with obesity.

O'Dell SD, Bujac SR, Miller GJ, Day IN.

Eur J Hum Genet. 1999 Oct-Nov;7(7):821-7.PMID: 10573016 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

Muller YL, Infante AM, Hanson RL, Love-Gregory L, Knowler W, Bogardus C, Baier LJ.

Diabetes. 2005 Oct;54(10):3035-9.PMID: 16186411 [PubMed - indexed for MEDLINE]Related articlesFree article

Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians.

Vozarova de Courten B, Hanson RL, Funahashi T, Lindsay RS, Matsuzawa Y, Tanaka S, Thameem F, Gruber JD, Froguel P, Wolford JK.

Diabetes. 2005 Jan;54(1):284-9.PMID: 15616040 [PubMed - indexed for MEDLINE]Related articlesFree article

HLA DRB1, DQB1 and insulin promoter VNTR polymorphisms: interactions and the association with adult-onset diabetes mellitus in Czech patients.

Cejkova P, Novota P, Cerna M, Kolostova K, Novakova D, Kucera P, Novak J, Andel M, Weber P, Zdarsky E.

Int J Immunogenet. 2008 Apr;35(2):133-40. Epub 2008 Feb 11.PMID: 18279373 [PubMed - indexed for MEDLINE]Related articles

INS VNTR is not associated with childhood obesity in 1,023 families: a family-based study.

Bouatia-Naji N, De Graeve F, Brönner G, Lecoeur C, Vatin V, Durand E, Lichtner P, Nguyen TT, Heude B, Weill J, Lévy-Marchal C, Hebebrand J, Froguel P, Meyre D.

Obesity (Silver Spring). 2008 Jun;16(6):1471-5. Epub 2008 Apr 3.PMID: 18388898 [PubMed - indexed for MEDLINE]Related articles

Insulin gene/IDDM2 locus in Japanese type 1 diabetes: contribution of class I alleles and influence of class I subdivision in susceptibility to type 1 diabetes.

Awata T, Kawasaki E, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Iizuka H, Kurihara S, Osaki M, Uga M, Kawabata Y, Tanaka S, Kanazawa Y, Katayama S.

J Clin Endocrinol Metab. 2007 May;92(5):1791-5. Epub 2007 Mar 6.PMID: 17341563 [PubMed - indexed for MEDLINE]Related articlesFree article

Variable number of tandem repeats of the insulin gene determines susceptibility to latent autoimmune diabetes in adults.

Cerrone GE, Caputo M, Lopez AP, González C, Massa C, Cédola N, Targovnik HM, Frechtel GD.

Mol Diagn. 2004;8(1):43-9.PMID: 15230641 [PubMed - indexed for MEDLINE]Related articles

Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type 1 diabetes.

Vafiadis P, Ounissi-Benkalha H, Palumbo M, Grabs R, Rousseau M, Goodyer CG, Polychronakos C.

J Clin Endocrinol Metab. 2001 Aug;86(8):3705-10.PMID: 11502799 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic variations within the insulin gene region are associated with accelerated fetal growth.

Osada H, Seki K, Sekiya S.

Tohoku J Exp Med. 2007 May;212(1):27-34.PMID: 17464100 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin gene variable number of tandem repeat genotype and the low birth weight, precocious pubarche, and hyperinsulinism sequence.

Ibáñez L, Ong K, Potau N, Marcos MV, de Zegher F, Dunger D.

J Clin Endocrinol Metab. 2001 Dec;86(12):5788-93.PMID: 11739440 [PubMed - indexed for MEDLINE]Related articlesFree article