PubMed

Measurements of insulin secretory capacity and glucose tolerance to predict pancreatic beta-cell mass in vivo in the nicotinamide/streptozotocin Göttingen minipig, a model of moderate insulin deficiency and diabetes.

Larsen MO, Rolin B, Wilken M, Carr RD, Gotfredsen CF.

Diabetes. 2003 Jan;52(1):118-23.PMID: 12502501 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas.

Larsen MO, Rolin B, Gotfredsen CF, Carr RD, Holst JJ.

Diabetologia. 2004 Nov;47(11):1873-8. Epub 2004 Nov 24.PMID: 15565374 [PubMed - indexed for MEDLINE]Related articles

Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Göttingen minipigs in vivo.

Larsen MO, Rolin B, Sturis J, Wilken M, Carr RD, Pørksen N, Gotfredsen CF.

Am J Physiol Endocrinol Metab. 2006 Apr;290(4):E670-7. Epub 2005 Nov 8.PMID: 16278249 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell function and mass in type 2 diabetes.

Larsen MO.

Dan Med Bull. 2009 Aug;56(3):153-64.PMID: 19728971 [PubMed - indexed for MEDLINE]Related articles

Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes.

Larsen MO, Wilken M, Gotfredsen CF, Carr RD, Svendsen O, Rolin B.

Am J Physiol Endocrinol Metab. 2002 Jun;282(6):E1342-51.PMID: 12006365 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell function and islet morphology in normal, obese, and obese beta-cell mass-reduced Göttingen minipigs.

Larsen MO, Juhl CB, Pørksen N, Gotfredsen CF, Carr RD, Ribel U, Wilken M, Rolin B.

Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E412-21. Epub 2004 Oct 12.PMID: 15479954 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of beta-cell mass leads to a reduction of pulse mass with normal periodicity, regularity and entrainment of pulsatile insulin secretion in Göttingen minipigs.

Larsen MO, Gotfredsen CF, Wilken M, Carr RD, Pørksen N, Rolin B.

Diabetologia. 2003 Feb;46(2):195-202. Epub 2003 Jan 11. Erratum in: Diabetologia. 2004 Jan;47(1):155. PMID: 12627318 [PubMed - indexed for MEDLINE]Related articles

Insulin sensitivity and beta-cell secretion in thalassaemia major with secondary haemochromatosis: assessment by oral glucose tolerance test.

Cario H, Holl RW, Debatin KM, Kohne E.

Eur J Pediatr. 2003 Mar;162(3):139-46. Epub 2003 Jan 15.PMID: 12655415 [PubMed - indexed for MEDLINE]Related articles

Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test.

Festa A, Williams K, Hanley AJ, Haffner SM.

Diabetes. 2008 Jun;57(6):1638-44. Epub 2008 Mar 10.PMID: 18332099 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of beta-cell mass and function in the Göttingen minipig.

Larsen MO, Rolin B, Raun K, Bjerre Knudsen L, Gotfredsen CF, Bock T.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:170-9.PMID: 17919191 [PubMed - indexed for MEDLINE]Related articles

Cholecystokinin octapeptide: a potential growth factor for pancreatic beta cells in diabetic rats.

Kuntz E, Pinget M, Damgé P.

JOP. 2004 Nov 10;5(6):464-75.PMID: 15536283 [PubMed - indexed for MEDLINE]Related articlesFree article

Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell mass.

Larsen MO, Rolin B, Ribel U, Wilken M, Deacon CF, Svendsen O, Gotfredsen CF, Carr RD.

Exp Diabesity Res. 2003 Apr-Jun;4(2):93-105.PMID: 14630571 [PubMed - indexed for MEDLINE]Related articlesFree article

Meal and oral glucose tests for assessment of beta -cell function: modeling analysis in normal subjects.

Mari A, Schmitz O, Gastaldelli A, Oestergaard T, Nyholm B, Ferrannini E.

Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1159-66. Epub 2002 Aug 6.PMID: 12388151 [PubMed - indexed for MEDLINE]Related articlesFree article

[Evaluation of islet beta cell function in subjects with normal glucose tolerance, impaired glucose regulation, and type 2 diabetes mellitus]

Liu J, Li YB, Shao H, Li YX, Yuan YH, Xiao YB, Weng JP.

Zhonghua Yi Xue Za Zhi. 2007 May 15;87(18):1252-5. Chinese. PMID: 17686259 [PubMed - indexed for MEDLINE]Related articles

Correlations of in vivo beta-cell function tests with beta-cell mass and pancreatic insulin content in streptozocin-administered baboons.

McCulloch DK, Koerker DJ, Kahn SE, Bonner-Weir S, Palmer JP.

Diabetes. 1991 Jun;40(6):673-9.PMID: 2040383 [PubMed - indexed for MEDLINE]Related articles

The impact of insulin resistance on proinsulin secretion in pregnancy: hyperproinsulinemia is not a feature of gestational diabetes.

Retnakaran R, Hanley AJ, Sermer M, Zinman B.

Diabetes Care. 2005 Nov;28(11):2710-5.PMID: 16249544 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans.

Fritsche A, Madaus A, Stefan N, Tschritter O, Maerker E, Teigeler A, Häring H, Stumvoll M.

Diabetes. 2002 Feb;51 Suppl 1:S234-9.PMID: 11815485 [PubMed - indexed for MEDLINE]Related articlesFree article

Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig.

Kjems LL, Kirby BM, Welsh EM, Veldhuis JD, Straume M, McIntyre SS, Yang D, Lefèbvre P, Butler PC.

Diabetes. 2001 Sep;50(9):2001-12.PMID: 11522665 [PubMed - indexed for MEDLINE]Related articlesFree article

Successful islet autotransplantation in humans: functional insulin secretory reserve as an estimate of surviving islet cell mass.

Teuscher AU, Kendall DM, Smets YF, Leone JP, Sutherland DE, Robertson RP.

Diabetes. 1998 Mar;47(3):324-30.PMID: 9519735 [PubMed - indexed for MEDLINE]Related articlesFree article

[A study of the degrees of insulin resistance and first-phase insulin secretion of beta-cells in metabolic syndrome patients with different glucose tolerance]

Hong J, Gu WQ, Zhang YF, Guo Y, Chen HM, Zhang LZ, Zhao YJ, Ning G.

Zhonghua Yi Xue Za Zhi. 2003 Nov 25;83(22):1952-6. Chinese. PMID: 14703429 [PubMed - indexed for MEDLINE]Related articles