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    Results: 1 to 20 of 565

    1.

    Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.

    Gum RJ, Gaede LL, Koterski SL, Heindel M, Clampit JE, Zinker BA, Trevillyan JM, Ulrich RG, Jirousek MR, Rondinone CM.

    Diabetes. 2003 Jan;52(1):21-8.PMID: 12502489 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells.

    Clampit JE, Meuth JL, Smith HT, Reilly RM, Jirousek MR, Trevillyan JM, Rondinone CM.

    Biochem Biophys Res Commun. 2003 Jan 10;300(2):261-7.PMID: 12504077 [PubMed - indexed for MEDLINE]Related articles

    3.

    Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation.

    Venable CL, Frevert EU, Kim YB, Fischer BM, Kamatkar S, Neel BG, Kahn BB.

    J Biol Chem. 2000 Jun 16;275(24):18318-26.PMID: 10751417 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice.

    Gum RJ, Gaede LL, Heindel MA, Waring JF, Trevillyan JM, Zinker BA, Stark ME, Wilcox D, Jirousek MR, Rondinone CM, Ulrich RG.

    Mol Endocrinol. 2003 Jun;17(6):1131-43. Epub 2003 Mar 20.PMID: 12649327 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes.

    Gonzalez-Rodriguez A, Clampit JE, Escribano O, Benito M, Rondinone CM, Valverde AM.

    Endocrinology. 2007 Feb;148(2):594-608. Epub 2006 Oct 26.PMID: 17068137 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Cellular effects of small molecule PTP1B inhibitors on insulin signaling.

    Xie L, Lee SY, Andersen JN, Waters S, Shen K, Guo XL, Moller NP, Olefsky JM, Lawrence DS, Zhang ZY.

    Biochemistry. 2003 Nov 11;42(44):12792-804.PMID: 14596593 [PubMed - indexed for MEDLINE]Related articles

    7.

    Reduction of low molecular weight protein-tyrosine phosphatase expression improves hyperglycemia and insulin sensitivity in obese mice.

    Pandey SK, Yu XX, Watts LM, Michael MD, Sloop KW, Rivard AR, Leedom TA, Manchem VP, Samadzadeh L, McKay RA, Monia BP, Bhanot S.

    J Biol Chem. 2007 May 11;282(19):14291-9. Epub 2007 Mar 12.PMID: 17353188 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.

    Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, Tiganis T.

    Mol Cell Biol. 2005 Jan;25(2):819-29.PMID: 15632081 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells.

    Egawa K, Maegawa H, Shimizu S, Morino K, Nishio Y, Bryer-Ash M, Cheung AT, Kolls JK, Kikkawa R, Kashiwagi A.

    J Biol Chem. 2001 Mar 30;276(13):10207-11. Epub 2001 Jan 2.PMID: 11136729 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Modulation of IR/PTP1B interaction and downstream signaling in insulin sensitive tissues of MSG-rats.

    Hirata AE, Alvarez-Rojas F, Carvalheira JB, Carvalho CR, Dolnikoff MS, Abdalla Saad MJ.

    Life Sci. 2003 Aug 1;73(11):1369-81.PMID: 12850498 [PubMed - indexed for MEDLINE]Related articles

    11.

    Acute selective glycogen synthase kinase-3 inhibition enhances insulin signaling in prediabetic insulin-resistant rat skeletal muscle.

    Dokken BB, Sloniger JA, Henriksen EJ.

    Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1188-94. Epub 2005 Jan 25.PMID: 15671078 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver.

    Nakagawa Y, Aoki N, Aoyama K, Shimizu H, Shimano H, Yamada N, Miyazaki H.

    Zoolog Sci. 2005 Feb;22(2):169-75.PMID: 15738637 [PubMed - indexed for MEDLINE]Related articles

    13.

    Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes.

    Shimizu S, Maegawa H, Egawa K, Shi K, Bryer-Ash M, Kashiwagi A.

    Endocrinology. 2002 Dec;143(12):4563-9.PMID: 12446583 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.

    Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB.

    Diabetes. 1999 Feb;48(2):310-20.PMID: 10334307 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

    Ogihara T, Asano T, Ando K, Chiba Y, Sekine N, Sakoda H, Anai M, Onishi Y, Fujishiro M, Ono H, Shojima N, Inukai K, Fukushima Y, Kikuchi M, Fujita T.

    Diabetes. 2001 Mar;50(3):573-83.PMID: 11246877 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.

    Laviola L, Belsanti G, Davalli AM, Napoli R, Perrini S, Weir GC, Giorgino R, Giorgino F.

    Diabetes. 2001 Dec;50(12):2709-20.PMID: 11723053 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance.

    Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB.

    J Biol Chem. 2007 Aug 17;282(33):23829-40. Epub 2007 Jun 1.PMID: 17545163 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats.

    Wu Y, Ouyang JP, Wu K, Wang SS, Wen CY, Xia ZY.

    Br J Pharmacol. 2005 Sep;146(2):234-43.PMID: 15997237 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.

    Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV.

    J Biol Chem. 2004 Jun 11;279(24):24929-34. Epub 2004 Apr 6.PMID: 15069067 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Protein-tyrosine-phosphatase 1B activation is regulated developmentally in muscle of neonatal pigs.

    Suryawan A, Davis TA.

    Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E47-54. Epub 2002 Sep 11.PMID: 12388170 [PubMed - indexed for MEDLINE]Related articlesFree article

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