PubMed

Endoplasmic reticulum stress and the development of diabetes: a review.

Harding HP, Ron D.

Diabetes. 2002 Dec;51 Suppl 3:S455-61. Review.PMID: 12475790 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of endoplasmic reticulum stress pathway on pancreatic beta-cells and diabetes mellitus.

Araki E, Oyadomari S, Mori M.

Exp Biol Med (Maywood). 2003 Nov;228(10):1213-7. Review.PMID: 14610263 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress and diabetes mellitus.

Araki E, Oyadomari S, Mori M.

Intern Med. 2003 Jan;42(1):7-14. Review.PMID: 12583611 [PubMed - indexed for MEDLINE]Related articlesFree article

The role for endoplasmic reticulum stress in diabetes mellitus.

Eizirik DL, Cardozo AK, Cnop M.

Endocr Rev. 2008 Feb;29(1):42-61. Epub 2007 Nov 29. Review.PMID: 18048764 [PubMed - indexed for MEDLINE]Related articlesFree article

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.PMID: 17906960 [PubMed - indexed for MEDLINE]Related articles

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.

Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D.

Mol Cell. 2001 Jun;7(6):1153-63.PMID: 11430819 [PubMed - indexed for MEDLINE]Related articles

Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells.

Oyadomari S, Araki E, Mori M.

Apoptosis. 2002 Aug;7(4):335-45. Review.PMID: 12101393 [PubMed - indexed for MEDLINE]Related articles

Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic beta-cells via transcriptional activation.

Ueda K, Kawano J, Takeda K, Yujiri T, Tanabe K, Anno T, Akiyama M, Nozaki J, Yoshinaga T, Koizumi A, Shinoda K, Oka Y, Tanizawa Y.

Eur J Endocrinol. 2005 Jul;153(1):167-76.PMID: 15994758 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling through phosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells.

Srinivasan S, Ohsugi M, Liu Z, Fatrai S, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2005 Apr;54(4):968-75.PMID: 15793234 [PubMed - indexed for MEDLINE]Related articlesFree article

Endoplasmic reticulum (ER) stress & diabetes.

Sundar Rajan S, Srinivasan V, Balasubramanyam M, Tatu U.

Indian J Med Res. 2007 Mar;125(3):411-24. Review.PMID: 17496365 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK.

Ladiges WC, Knoblaugh SE, Morton JF, Korth MJ, Sopher BL, Baskin CR, MacAuley A, Goodman AG, LeBoeuf RC, Katze MG.

Diabetes. 2005 Apr;54(4):1074-81.PMID: 15793246 [PubMed - indexed for MEDLINE]Related articlesFree article

Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis.

Casas S, Gomis R, Gribble FM, Altirriba J, Knuutila S, Novials A.

Diabetes. 2007 Sep;56(9):2284-94. Epub 2007 Jun 11.PMID: 17563070 [PubMed - indexed for MEDLINE]Related articlesFree article

[Unfolded protein response: its role in physiology and physiopathology]

Foufelle F, Ferré P.

Med Sci (Paris). 2007 Mar;23(3):291-6. Review. French. PMID: 17349291 [PubMed - indexed for MEDLINE]Related articles

Dietary toxins, endoplasmic reticulum (ER) stress and diabetes.

Hettiarachchi KD, Zimmet PZ, Myers MA.

Curr Diabetes Rev. 2008 May;4(2):146-56. Review.PMID: 18473761 [PubMed - indexed for MEDLINE]Related articles

ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.

Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tashiro F, Aburatani H, Tsukiyama-Kohara K, Miyazaki J, Sonenberg N, Oka Y.

Cell Metab. 2008 Mar;7(3):269-76.PMID: 18316032 [PubMed - indexed for MEDLINE]Related articles

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.

Pavio N, Romano PR, Graczyk TM, Feinstone SM, Taylor DR.

J Virol. 2003 Mar;77(6):3578-85.PMID: 12610133 [PubMed - indexed for MEDLINE]Related articlesFree article

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.

Liang SH, Zhang W, McGrath BC, Zhang P, Cavener DR.

Biochem J. 2006 Jan 1;393(Pt 1):201-9.PMID: 16124869 [PubMed - indexed for MEDLINE]Related articlesFree article

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.

Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D.

Genes Dev. 2004 Dec 15;18(24):3066-77.PMID: 15601821 [PubMed - indexed for MEDLINE]Related articlesFree article

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.

Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR.

Mol Cell Biol. 2002 Jun;22(11):3864-74.PMID: 11997520 [PubMed - indexed for MEDLINE]Related articlesFree article

GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress.

Yusta B, Baggio LL, Estall JL, Koehler JA, Holland DP, Li H, Pipeleers D, Ling Z, Drucker DJ.

Cell Metab. 2006 Nov;4(5):391-406.PMID: 17084712 [PubMed - indexed for MEDLINE]Related articles