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    Results: 1 to 20 of 159

    1.

    Glucagon-like peptide-1 receptor activation antagonizes voltage-dependent repolarizing K(+) currents in beta-cells: a possible glucose-dependent insulinotropic mechanism.

    MacDonald PE, Salapatek AM, Wheeler MB.

    Diabetes. 2002 Dec;51 Suppl 3:S443-7.PMID: 12475788 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Antagonism of rat beta-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways.

    MacDonald PE, Wang X, Xia F, El-kholy W, Targonsky ED, Tsushima RG, Wheeler MB.

    J Biol Chem. 2003 Dec 26;278(52):52446-53. Epub 2003 Oct 16.PMID: 14565957 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    cAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine receptors in pancreatic beta-cells. A Ca2+ signaling system stimulated by the insulinotropic hormone glucagon-like peptide-1-(7-37).

    Holz GG, Leech CA, Heller RS, Castonguay M, Habener JF.

    J Biol Chem. 1999 May 14;274(20):14147-56.PMID: 10318832 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    cAMP-independent decrease of ATP-sensitive K+ channel activity by GLP-1 in rat pancreatic beta-cells.

    Suga S, Kanno T, Ogawa Y, Takeo T, Kamimura N, Wakui M.

    Pflugers Arch. 2000 Aug;440(4):566-72.PMID: 10958340 [PubMed - indexed for MEDLINE]Related articles

    5.

    Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors.

    Moens K, Flamez D, Van Schravendijk C, Ling Z, Pipeleers D, Schuit F.

    Diabetes. 1998 Jan;47(1):66-72.PMID: 9421376 [PubMed - indexed for MEDLINE]Related articles

    6.

    New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells.

    Holz GG.

    Horm Metab Res. 2004 Nov-Dec;36(11-12):787-94. Erratum in: Horm Metab Res. 2005 Feb;37(2):126. Holz, G [corrected to Holz, GG]. PMID: 15655710 [PubMed - indexed for MEDLINE]Related articles

    7.

    A novel mechanism for the suppression of a voltage-gated potassium channel by glucose-dependent insulinotropic polypeptide: protein kinase A-dependent endocytosis.

    Kim SJ, Choi WS, Han JS, Warnock G, Fedida D, McIntosh CH.

    J Biol Chem. 2005 Aug 5;280(31):28692-700. Epub 2005 Jun 13.PMID: 15955806 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Altered cAMP and Ca2+ signaling in mouse pancreatic islets with glucagon-like peptide-1 receptor null phenotype.

    Flamez D, Gilon P, Moens K, Van Breusegem A, Delmeire D, Scrocchi LA, Henquin JC, Drucker DJ, Schuit F.

    Diabetes. 1999 Oct;48(10):1979-86.PMID: 10512362 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Mutations to the third cytoplasmic domain of the glucagon-like peptide 1 (GLP-1) receptor can functionally uncouple GLP-1-stimulated insulin secretion in HIT-T15 cells.

    Salapatek AM, MacDonald PE, Gaisano HY, Wheeler MB.

    Mol Endocrinol. 1999 Aug;13(8):1305-17.PMID: 10446905 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence.

    Serre V, Dolci W, Schaerer E, Scrocchi L, Drucker D, Efrat S, Thorens B.

    Endocrinology. 1998 Nov;139(11):4448-54.PMID: 9794451 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors.

    Gromada J, Ding WG, Barg S, Renström E, Rorsman P.

    Pflugers Arch. 1997 Sep;434(5):515-24.PMID: 9242714 [PubMed - indexed for MEDLINE]Related articles

    12.

    Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.

    Gromada J, Bokvist K, Ding WG, Holst JJ, Nielsen JH, Rorsman P.

    Diabetes. 1998 Jan;47(1):57-65.PMID: 9421375 [PubMed - indexed for MEDLINE]Related articles

    13.

    GLP-I(7-36) amide augments Ba2+ current through L-type Ca2+ channel of rat pancreatic beta-cell in a cAMP-dependent manner.

    Suga S, Kanno T, Nakano K, Takeo T, Dobashi Y, Wakui M.

    Diabetes. 1997 Nov;46(11):1755-60.PMID: 9356022 [PubMed - indexed for MEDLINE]Related articles

    14.

    The recombinant rat glucagon-like peptide-1 receptor, expressed in an alpha-cell line, is coupled to adenylyl cyclase activation and intracellular calcium release.

    Dillon JS, Lu M, Bowen S, Homan LL.

    Exp Clin Endocrinol Diabetes. 2005 Mar;113(3):182-9.PMID: 15789279 [PubMed - indexed for MEDLINE]Related articles

    15.

    Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids.

    Feng DD, Luo Z, Roh SG, Hernandez M, Tawadros N, Keating DJ, Chen C.

    Endocrinology. 2006 Feb;147(2):674-82. Epub 2005 Oct 27.PMID: 16254037 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.

    Nakazaki M, Crane A, Hu M, Seghers V, Ullrich S, Aguilar-Bryan L, Bryan J.

    Diabetes. 2002 Dec;51(12):3440-9.PMID: 12453898 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Ghrelin uses Galphai2 and activates voltage-dependent K+ channels to attenuate glucose-induced Ca2+ signaling and insulin release in islet beta-cells: novel signal transduction of ghrelin.

    Dezaki K, Kakei M, Yada T.

    Diabetes. 2007 Sep;56(9):2319-27. Epub 2007 Jun 15.PMID: 17575083 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

    MacDonald PE, Sewing S, Wang J, Joseph JW, Smukler SR, Sakellaropoulos G, Wang J, Saleh MC, Chan CB, Tsushima RG, Salapatek AM, Wheeler MB.

    J Biol Chem. 2002 Nov 22;277(47):44938-45. Epub 2002 Sep 20.PMID: 12270920 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Pertussis toxin-sensitive pathway inhibits glucose-stimulated Ca2+ signals of rat islet beta-cells by affecting L-type Ca2+ channels and voltage-dependent K+ channels.

    Suga S, Takeo T, Nakano K, Sato T, Igarashi T, Yamana D, Wakui M.

    Cell Calcium. 2004 Dec;36(6):469-77.PMID: 15488596 [PubMed - indexed for MEDLINE]Related articles

    20.

    Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A- and ADP-dependent mechanism.

    Light PE, Manning Fox JE, Riedel MJ, Wheeler MB.

    Mol Endocrinol. 2002 Sep;16(9):2135-44.PMID: 12198249 [PubMed - indexed for MEDLINE]Related articlesFree article

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