My NCBI | Sign In
RSS Settings
  • Search:

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

    Results: 1 to 20 of 118

    1.

    Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes.

    Prentki M, Joly E, El-Assaad W, Roduit R.

    Diabetes. 2002 Dec;51 Suppl 3:S405-13. Review.PMID: 12475783 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

    Prentki M, Corkey BE.

    Diabetes. 1996 Mar;45(3):273-83. Review.PMID: 8593930 [PubMed - indexed for MEDLINE]Related articles

    3.

    Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell.

    Roduit R, Morin J, Massé F, Segall L, Roche E, Newgard CB, Assimacopoulos-Jeannet F, Prentki M.

    J Biol Chem. 2000 Nov 17;275(46):35799-806.PMID: 10967113 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Fatty acid signaling in the beta-cell and insulin secretion.

    Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M.

    Diabetes. 2006 Dec;55 Suppl 2:S16-23. Review.PMID: 17130640 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.

    Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M.

    Diabetes. 2004 Apr;53(4):1007-19.PMID: 15047616 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

    Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

    Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells.

    Corkey BE, Glennon MC, Chen KS, Deeney JT, Matschinsky FM, Prentki M.

    J Biol Chem. 1989 Dec 25;264(36):21608-12.PMID: 2689441 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction.

    Corkey BE, Deeney JT, Yaney GC, Tornheim K, Prentki M.

    J Nutr. 2000 Feb;130(2S Suppl):299S-304S. Review.PMID: 10721892 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression.

    Roche E, Farfari S, Witters LA, Assimacopoulos-Jeannet F, Thumelin S, Brun T, Corkey BE, Saha AK, Prentki M.

    Diabetes. 1998 Jul;47(7):1086-94.PMID: 9648832 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    [Fatty acids and beta cells]

    Girard J.

    Diabetes Metab. 2000 Jun;26 Suppl 3:6-9. Review. French. PMID: 10945143 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Glucolipotoxicity: fuel excess and beta-cell dysfunction.

    Poitout V, Robertson RP.

    Endocr Rev. 2008 May;29(3):351-66. Epub 2007 Nov 29. Review.PMID: 18048763 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity.

    Poitout V, Robertson RP.

    Endocrinology. 2002 Feb;143(2):339-42. Review.PMID: 11796484 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity.

    Dulloo AG, Gubler M, Montani JP, Seydoux J, Solinas G.

    Int J Obes Relat Metab Disord. 2004 Dec;28 Suppl 4:S29-37. Review.PMID: 15592483 [PubMed - indexed for MEDLINE]Related articles

    14.

    Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

    Diraison F, Parton L, Ferré P, Foufelle F, Briscoe CP, Leclerc I, Rutter GA.

    Biochem J. 2004 Mar 15;378(Pt 3):769-78.PMID: 14690455 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    [Contribution of free fatty acids to impairment of insulin secretion and action. mechanism of beta-cell lipotoxicity]

    Girard J.

    Med Sci (Paris). 2005 Dec;21 Spec No:19-25. French. PMID: 16598900 [PubMed - indexed for MEDLINE]Related articles

    16.

    Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.

    El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, Hardy S, Joly E, Dbaibo G, Rosenberg L, Prentki M.

    Endocrinology. 2003 Sep;144(9):4154-63.PMID: 12933690 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Glucose-fatty acid interactions in health and disease.

    McGarry JD.

    Am J Clin Nutr. 1998 Mar;67(3 Suppl):500S-504S. Review.PMID: 9497160 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Non-esterified fatty acids are deleterious for human pancreatic islet function at physiological glucose concentration.

    Dubois M, Kerr-Conte J, Gmyr V, Bouckenooghe T, Muharram G, D'Herbomez M, Martin-Ponthieu A, Vantyghem MC, Vandewalle B, Pattou F.

    Diabetologia. 2004 Mar;47(3):463-9. Epub 2004 Feb 13.PMID: 14968298 [PubMed - indexed for MEDLINE]Related articles

    19.

    Aspects of novel sites of regulation of the insulin stimulus-secretion coupling in normal and diabetic pancreatic islets.

    Sjöholm A.

    Endocrine. 1998 Aug;9(1):1-13. Review.PMID: 9798725 [PubMed - indexed for MEDLINE]Related articles

    20.

    Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates.

    Jobgen WS, Fried SK, Fu WJ, Meininger CJ, Wu G.

    J Nutr Biochem. 2006 Sep;17(9):571-88. Epub 2006 Jan 9. Review.PMID: 16524713 [PubMed - indexed for MEDLINE]Related articles

    Supplemental Content

    Filter your results:

    Find related data

    Recent activity