PubMed

Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.

Lippiat JD, Albinson SL, Ashcroft FM.

Diabetes. 2002 Dec;51 Suppl 3:S377-80.PMID: 12475778 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer.

Tsuboi T, Lippiat JD, Ashcroft FM, Rutter GA.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):76-81. Epub 2003 Dec 17.PMID: 14681552 [PubMed - indexed for MEDLINE]Related articlesFree article

The carboxyl termini of K(ATP) channels bind nucleotides.

Vanoye CG, MacGregor GG, Dong K, Tang L, Buschmann AS, Hall AE, Lu M, Giebisch G, Hebert SC.

J Biol Chem. 2002 Jun 28;277(26):23260-70. Epub 2002 Apr 15.PMID: 11956191 [PubMed - indexed for MEDLINE]Related articlesFree article

Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels.

Rainbow RD, James M, Hudman D, Al Johi M, Singh H, Watson PJ, Ashmole I, Davies NW, Lodwick D, Norman RI.

Biochem J. 2004 Apr 1;379(Pt 1):173-81.PMID: 14672537 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide.

Gribble FM, Ashcroft FM.

Diabetologia. 1999 Jul;42(7):845-8.PMID: 10440127 [PubMed - indexed for MEDLINE]Related articles

Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides.

Reimann F, Dabrowski M, Jones P, Gribble FM, Ashcroft FM.

J Physiol. 2003 Feb 15;547(Pt 1):159-68. Epub 2003 Jan 10.PMID: 12562963 [PubMed - indexed for MEDLINE]Related articlesFree article

Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.

Hansen AM, Hansen JB, Carr RD, Ashcroft FM, Wahl P.

Br J Pharmacol. 2005 Feb;144(4):551-7.PMID: 15678092 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfonylurea receptors type 1 and 2A randomly assemble to form heteromeric KATP channels of mixed subunit composition.

Chan KW, Wheeler A, Csanády L.

J Gen Physiol. 2008 Jan;131(1):43-58. Epub 2007 Dec 17.PMID: 18079561 [PubMed - indexed for MEDLINE]Related articlesFree article

Localization of the ATP/phosphatidylinositol 4,5 diphosphate-binding site to a 39-amino acid region of the carboxyl terminus of the ATP-regulated K+ channel Kir1.1.

Dong K, Tang L, MacGregor GG, Hebert SC.

J Biol Chem. 2002 Dec 20;277(51):49366-73. Epub 2002 Oct 14.PMID: 12381730 [PubMed - indexed for MEDLINE]Related articlesFree article

Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic beta-cell-type K(ATP) channels.

Chachin M, Yamada M, Fujita A, Matsuoka T, Matsushita K, Kurachi Y.

J Pharmacol Exp Ther. 2003 Mar;304(3):1025-32.PMID: 12604678 [PubMed - indexed for MEDLINE]Related articlesFree article

Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes.

Lim JG, Lee HY, Yun JE, Kim SP, Park JW, Suh SI, Jang BC, Cho CH, Bae JH, Kim SS, Han J, Park MJ, Song DK.

Biochem Pharmacol. 2004 Sep 1;68(5):901-10.PMID: 15294453 [PubMed - indexed for MEDLINE]Related articles

A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K(+) channels.

Yamada M, Kurachi Y.

J Mol Cell Cardiol. 2005 Jul;39(1):1-6. Epub 2005 Feb 5.PMID: 15978900 [PubMed - indexed for MEDLINE]Related articles

A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.

Tammaro P, Ashcroft FM.

J Physiol. 2007 Nov 1;584(Pt 3):743-53. Epub 2007 Sep 13.PMID: 17855752 [PubMed - indexed for MEDLINE]Related articlesFree article

Flow cytometric measurement of fluorescence (Förster) resonance energy transfer from cyan fluorescent protein to yellow fluorescent protein using single-laser excitation at 458 nm.

He L, Bradrick TD, Karpova TS, Wu X, Fox MH, Fischer R, McNally JG, Knutson JR, Grammer AC, Lipsky PE.

Cytometry A. 2003 May;53(1):39-54.PMID: 12701131 [PubMed - indexed for MEDLINE]Related articlesFree article

Testing the bipartite model of the sulfonylurea receptor binding site: binding of A-, B-, and A + B-site ligands.

Winkler M, Stephan D, Bieger S, Kühner P, Wolff F, Quast U.

J Pharmacol Exp Ther. 2007 Aug;322(2):701-8. Epub 2007 May 10.PMID: 17495126 [PubMed - indexed for MEDLINE]Related articlesFree article

Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A.

Cui Y, Tinker A, Clapp LH.

Br J Pharmacol. 2003 May;139(1):122-8.PMID: 12746230 [PubMed - indexed for MEDLINE]Related articlesFree article

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.

Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO.

Diabetologia. 2007 Aug;50(8):1670-7. Epub 2007 May 24.PMID: 17522836 [PubMed - indexed for MEDLINE]Related articles

Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.

Chen M, Dong Y, Simard JM.

J Neurosci. 2003 Sep 17;23(24):8568-77.PMID: 13679426 [PubMed - indexed for MEDLINE]Related articlesFree article

The N-terminal transmembrane domain (TMD0) and a cytosolic linker (L0) of sulphonylurea receptor define the unique intrinsic gating of KATP channels.

Fang K, Csanády L, Chan KW.

J Physiol. 2006 Oct 15;576(Pt 2):379-89. Epub 2006 Aug 3.PMID: 16887879 [PubMed - indexed for MEDLINE]Related articlesFree article

Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.

Pearson ER, Flechtner I, Njølstad PR, Malecki MT, Flanagan SE, Larkin B, Ashcroft FM, Klimes I, Codner E, Iotova V, Slingerland AS, Shield J, Robert JJ, Holst JJ, Clark PM, Ellard S, Søvik O, Polak M, Hattersley AT; Neonatal Diabetes International Collaborative Group.

N Engl J Med. 2006 Aug 3;355(5):467-77.PMID: 16885550 [PubMed - indexed for MEDLINE]Related articlesFree article