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Genetics of obesity and type 2 diabetes: tracking pathogenic traits during the predisease period.

Bougnères P.

Diabetes. 2002 Dec;51 Suppl 3:S295-303. Review.PMID: 12475766 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic epidemiology of diabetes.

Permutt MA, Wasson J, Cox N.

J Clin Invest. 2005 Jun;115(6):1431-9. Review.PMID: 15931378 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative genomics: exploring the genetic architecture of complex trait predisposition.

Pomp D, Allan MF, Wesolowski SR.

J Anim Sci. 2004;82 E-Suppl:E300-312. Review.PMID: 15471811 [PubMed - indexed for MEDLINE]Related articlesFree article

Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects.

Gjesing AP, Andersen G, Burgdorf KS, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2007 Mar;50(3):563-8. Epub 2007 Jan 13.PMID: 17221209 [PubMed - indexed for MEDLINE]Related articles

Regulatory polymorphisms underlying complex disease traits.

Knight JC.

J Mol Med. 2005 Feb;83(2):97-109. Epub 2004 Dec 9. Review.PMID: 15592805 [PubMed - indexed for MEDLINE]Related articles

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Mohlke KL, Boehnke M, Abecasis GR.

Hum Mol Genet. 2008 Oct 15;17(R2):R102-8.PMID: 18852197 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic modifiers interact with Cpe(fat) to affect body weight, adiposity, and hyperglycemia.

Collin GB, Maddatu TP, Sen S, Naggert JK.

Physiol Genomics. 2005 Jul 14;22(2):182-90. Epub 2005 May 3.PMID: 15870393 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population.

Cheyssac C, Lecoeur C, Dechaume A, Bibi A, Charpentier G, Balkau B, Marre M, Froguel P, Gibson F, Vaxillaire M.

BMC Med Genet. 2006 May 5;7:44.PMID: 16677372 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of genetic variation in ENPP1 with obesity-related phenotypes.

Jenkinson CP, Coletta DK, Flechtner-Mors M, Hu SL, Fourcaudot MJ, Rodriguez LM, Schneider J, Arya R, Stern MP, Blangero J, Duggirala R, DeFronzo RA.

Obesity (Silver Spring). 2008 Jul;16(7):1708-13. Epub 2008 May 8.PMID: 18464750 [PubMed - indexed for MEDLINE]Related articles

Genetic variation in BEACON influences quantitative variation in metabolic syndrome-related phenotypes.

Jowett JB, Elliott KS, Curran JE, Hunt N, Walder KR, Collier GR, Zimmet PZ, Blangero J.

Diabetes. 2004 Sep;53(9):2467-72.PMID: 15331561 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-specific genetic effects on obesity traits in American Indian populations: the Strong Heart Family Study.

Franceschini N, Almasy L, MacCluer JW, Göring HH, Cole SA, Diego VP, Laston S, Howard BV, Lee ET, Best LG, Fabsitz RR, North KE.

BMC Med Genet. 2008 Oct 14;9:90.PMID: 18854016 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait linkage studies of diabetes-related traits.

Hanson RL, Knowler WC.

Curr Diab Rep. 2003 Apr;3(2):176-83. Review.PMID: 12728644 [PubMed - indexed for MEDLINE]Related articles

[Pathophysiology and genetics of obesity]

Oberkofler H, Krempler F, Patsch W.

Wien Klin Wochenschr. 2002;114 Suppl 4:4-9. Review. German. PMID: 15499992 [PubMed - indexed for MEDLINE]Related articles

Mapping the genetic architecture of gene expression in human liver.

Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R.

PLoS Biol. 2008 May 6;6(5):e107.PMID: 18462017 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic dissection of obesity in polygenic animal models.

Pomp D.

Behav Genet. 1997 Jul;27(4):285-306. Review.PMID: 9519558 [PubMed - indexed for MEDLINE]Related articles

Pharmacogenetics: potential role in the treatment of diabetes and obesity.

Vella A, Camilleri M.

Expert Opin Pharmacother. 2008 May;9(7):1109-19. Review.PMID: 18422469 [PubMed - indexed for MEDLINE]Related articles

Common and rare alleles as causes of complex phenotypes.

Polychronakos C.

Curr Atheroscler Rep. 2008 Jun;10(3):194-200. Review.PMID: 18489846 [PubMed - indexed for MEDLINE]Related articles

Genetical genomics: combining genetics with gene expression analysis.

Li J, Burmeister M.

Hum Mol Genet. 2005 Oct 15;14 Spec No. 2:R163-9. Review.PMID: 16244315 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.

Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM.

Diabetes. 2008 May;57(5):1419-26. Epub 2008 Mar 17.PMID: 18346983 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.

Conneely KN, Silander K, Scott LJ, Mohlke KL, Lazaridis KN, Valle TT, Tuomilehto J, Bergman RN, Watanabe RM, Buchanan TA, Collins FS, Boehnke M.

Diabetologia. 2004 Oct;47(10):1782-8. Epub 2004 Oct 27.PMID: 15517149 [PubMed - indexed for MEDLINE]Related articlesFree article