PubMed

Activation of tubular epithelial cells in diabetic nephropathy.

Morcos M, Sayed AA, Bierhaus A, Yard B, Waldherr R, Merz W, Kloeting I, Schleicher E, Mentz S, Abd el Baki RF, Tritschler H, Kasper M, Schwenger V, Hamann A, Dugi KA, Schmidt AM, Stern D, Ziegler R, Haering HU, Andrassy M, van der Woude F, Nawroth PP.

Diabetes. 2002 Dec;51(12):3532-44.PMID: 12453911 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.

Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Klöting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, Häring HU, Schleicher E, Nawroth PP.

Diabetes. 2001 Dec;50(12):2792-808.PMID: 11723063 [PubMed - indexed for MEDLINE]Related articlesFree article

Posttranslationally modified proteins as mediators of sustained intestinal inflammation.

Andrassy M, Igwe J, Autschbach F, Volz C, Remppis A, Neurath MF, Schleicher E, Humpert PM, Wendt T, Liliensiek B, Morcos M, Schiekofer S, Thiele K, Chen J, Kientsch-Engel R, Schmidt AM, Stremmel W, Stern DM, Katus HA, Nawroth PP, Bierhaus A.

Am J Pathol. 2006 Oct;169(4):1223-37.PMID: 17003481 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease.

Tanji N, Markowitz GS, Fu C, Kislinger T, Taguchi A, Pischetsrieder M, Stern D, Schmidt AM, D'Agati VD.

J Am Soc Nephrol. 2000 Sep;11(9):1656-66.PMID: 10966490 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of tubular epithelial cells in diabetic nephropathy and the role of the peroxisome proliferator-activated receptor-gamma agonist.

Tang SC, Leung JC, Chan LY, Tsang AW, Lai KN.

J Am Soc Nephrol. 2006 Jun;17(6):1633-43. Epub 2006 May 10.PMID: 16687627 [PubMed - indexed for MEDLINE]Related articlesFree article

The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy.

Haslbeck KM, Friess U, Schleicher ED, Bierhaus A, Nawroth PP, Kirchner A, Pauli E, Neundörfer B, Heuss D.

Acta Neuropathol. 2005 Sep;110(3):247-54. Epub 2005 Jun 29.PMID: 15986224 [PubMed - indexed for MEDLINE]Related articles

Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.

Quehenberger P, Bierhaus A, Fasching P, Muellner C, Klevesath M, Hong M, Stier G, Sattler M, Schleicher E, Speiser W, Nawroth PP.

Diabetes. 2000 Sep;49(9):1561-70.PMID: 10969841 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB.

Hofmann MA, Schiekofer S, Isermann B, Kanitz M, Henkels M, Joswig M, Treusch A, Morcos M, Weiss T, Borcea V, Abdel Khalek AK, Amiral J, Tritschler H, Ritz E, Wahl P, Ziegler R, Bierhaus A, Nawroth PP.

Diabetologia. 1999 Feb;42(2):222-32.PMID: 10064103 [PubMed - indexed for MEDLINE]Related articles

Glimepiride reduces mononuclear activation of the redox-sensitive transcription factor nuclear factor-kappa B.

Schiekofer S, Rudofsky G Jr, Andrassy M, Schneider J, Chen J, Isermann B, Kanitz M, Elsenhans S, Heinle H, Balletshofer B, Häring HU, Schleicher E, Nawroth PP, Bierhaus A.

Diabetes Obes Metab. 2003 Jul;5(4):251-61.PMID: 12795658 [PubMed - indexed for MEDLINE]Related articles

An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.

Nakamura S, Tachikawa T, Tobita K, Aoyama I, Takayama F, Enomoto A, Niwa T.

Am J Kidney Dis. 2003 Mar;41(3 Suppl 1):S68-71.PMID: 12612956 [PubMed - indexed for MEDLINE]Related articles

Role of receptor for advanced glycation end-products and signalling events in advanced glycation end-product-induced monocyte chemoattractant protein-1 expression in differentiated mouse podocytes.

Gu L, Hagiwara S, Fan Q, Tanimoto M, Kobata M, Yamashita M, Nishitani T, Gohda T, Ni Z, Qian J, Horikoshi S, Tomino Y.

Nephrol Dial Transplant. 2006 Feb;21(2):299-313. Epub 2005 Nov 1.PMID: 16263740 [PubMed - indexed for MEDLINE]Related articlesFree article

NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy.

Mezzano S, Aros C, Droguett A, Burgos ME, Ardiles L, Flores C, Schneider H, Ruiz-Ortega M, Egido J.

Nephrol Dial Transplant. 2004 Oct;19(10):2505-12. Epub 2004 Jul 27.PMID: 15280531 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells.

Bierhaus A, Chevion S, Chevion M, Hofmann M, Quehenberger P, Illmer T, Luther T, Berentshtein E, Tritschler H, Müller M, Wahl P, Ziegler R, Nawroth PP.

Diabetes. 1997 Sep;46(9):1481-90.PMID: 9287050 [PubMed - indexed for MEDLINE]Related articles

Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo.

Tang S, Leung JC, Abe K, Chan KW, Chan LY, Chan TM, Lai KN.

J Clin Invest. 2003 Feb;111(4):515-27.PMID: 12588890 [PubMed - indexed for MEDLINE]Related articlesFree article

Postprandial mononuclear NF-kappaB activation is independent of the AGE-content of a single meal.

Schiekofer S, Franke S, Andrassy M, Chen J, Rudofsky G, Schneider JG, von Eynatten M, Wendt T, Morcos M, Kientsch-Engel R, Stein G, Schleicher E, Nawroth PP, Bierhaus A.

Exp Clin Endocrinol Diabetes. 2006 Apr;114(4):160-7.PMID: 16705547 [PubMed - indexed for MEDLINE]Related articles

Detection of elevated N epsilon-carboxymethyllysine levels in muscular tissue and in serum of patients with fibromyalgia.

Rüster M, Franke S, Späth M, Pongratz DE, Stein G, Hein GE.

Scand J Rheumatol. 2005 Nov-Dec;34(6):460-3.PMID: 16393769 [PubMed - indexed for MEDLINE]Related articles

Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.

Forbes JM, Thorpe SR, Thallas-Bonke V, Pete J, Thomas MC, Deemer ER, Bassal S, El-Osta A, Long DM, Panagiotopoulos S, Jerums G, Osicka TM, Cooper ME.

J Am Soc Nephrol. 2005 Aug;16(8):2363-72. Epub 2005 Jun 1.PMID: 15930093 [PubMed - indexed for MEDLINE]Related articlesFree article

Thymoquinone decreases AGE-induced NF-kappaB activation in proximal tubular epithelial cells.

Sayed AA, Morcos M.

Phytother Res. 2007 Sep;21(9):898-9.PMID: 17582594 [PubMed - indexed for MEDLINE]Related articles

Nuclear factor-kappaB activation in diabetic rat kidney: evidence for involvement of P-selectin in diabetic nephropathy.

Iwamoto M, Mizuiri S, Arita M, Hemmi H.

Tohoku J Exp Med. 2005 Jun;206(2):163-71.PMID: 15888973 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily.

Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M, Sayed AA, Andrassy M, Schiekofer S, Schneider JG, Schulz JB, Heuss D, Neundörfer B, Dierl S, Huber J, Tritschler H, Schmidt AM, Schwaninger M, Haering HU, Schleicher E, Kasper M, Stern DM, Arnold B, Nawroth PP.

J Clin Invest. 2004 Dec;114(12):1741-51.PMID: 15599399 [PubMed - indexed for MEDLINE]Related articlesFree article