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    Results: 1 to 20 of 204

    1.

    Comparison of central and peripheral administration of C75 on food intake, body weight, and conditioned taste aversion.

    Clegg DJ, Wortman MD, Benoit SC, McOsker CC, Seeley RJ.

    Diabetes. 2002 Nov;51(11):3196-201.PMID: 12401710 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system.

    Proulx K, Cota D, Woods SC, Seeley RJ.

    Diabetes. 2008 Dec;57(12):3231-8. Epub 2008 Sep 5.PMID: 18776140 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight.

    Aja S, Landree LE, Kleman AM, Medghalchi SM, Vadlamudi A, McFadden JM, Aplasca A, Hyun J, Plummer E, Daniels K, Kemm M, Townsend CA, Thupari JN, Kuhajda FP, Moran TH, Ronnett GV.

    Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R352-61. Epub 2007 Dec 5.PMID: 18056987 [PubMed - indexed for MEDLINE]Related articles

    4.

    Differential effects of a centrally acting fatty acid synthase inhibitor in lean and obese mice.

    Kumar MV, Shimokawa T, Nagy TR, Lane MD.

    Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1921-5. Erratum in: Proc Natl Acad Sci U S A 2002 May 28;99(11):7809. PMID: 11854492 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    C75 alters central and peripheral gene expression to reduce food intake and increase energy expenditure.

    Tu Y, Thupari JN, Kim EK, Pinn ML, Moran TH, Ronnett GV, Kuhajda FP.

    Endocrinology. 2005 Jan;146(1):486-93. Epub 2004 Oct 21.PMID: 15498887 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Intraperitoneal injections of low doses of C75 elicit a behaviorally specific and vagal afferent-independent inhibition of eating in rats.

    Mansouri A, Aja S, Moran TH, Ronnett G, Kuhajda FP, Arnold M, Geary N, Langhans W, Leonhardt M.

    Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R799-805. Epub 2008 Jul 30.PMID: 18667714 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase.

    Kim EK, Miller I, Aja S, Landree LE, Pinn M, McFadden J, Kuhajda FP, Moran TH, Ronnett GV.

    J Biol Chem. 2004 May 7;279(19):19970-6. Epub 2004 Mar 17.PMID: 15028725 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Comparison of central administration of corticotropin-releasing hormone and urocortin on food intake, conditioned taste aversion, and c-Fos expression.

    Benoit SC, Thiele TE, Heinrichs SC, Rushing PA, Blake KA, Steeley RJ.

    Peptides. 2000 Mar;21(3):345-51.PMID: 10793215 [PubMed - indexed for MEDLINE]Related articles

    9.

    Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment.

    Kim EK, Miller I, Landree LE, Borisy-Rudin FF, Brown P, Tihan T, Townsend CA, Witters LA, Moran TH, Kuhajda FP, Ronnett GV.

    Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E867-79.PMID: 12376313 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Effect of centrally administered C75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice.

    Li LF, Lu YY, Xiong W, Liu JY, Chen Q.

    Eur J Pharmacol. 2008 Oct 24;595(1-3):90-4. Epub 2008 Jul 31.PMID: 18706411 [PubMed - indexed for MEDLINE]Related articles

    11.

    Long-term effects of a fatty acid synthase inhibitor on obese mice: food intake, hypothalamic neuropeptides, and UCP3.

    Cha SH, Hu Z, Lane MD.

    Biochem Biophys Res Commun. 2004 Apr 30;317(2):301-8.PMID: 15063757 [PubMed - indexed for MEDLINE]Related articles

    12.

    C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.

    Thupari JN, Landree LE, Ronnett GV, Kuhajda FP.

    Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502. Epub 2002 Jun 11.PMID: 12060712 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass.

    Thupari JN, Kim EK, Moran TH, Ronnett GV, Kuhajda FP.

    Am J Physiol Endocrinol Metab. 2004 Jul;287(1):E97-E104. Epub 2004 Jan 21.PMID: 14736702 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides.

    Shimokawa T, Kumar MV, Lane MD.

    Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):66-71. Epub 2001 Dec 26.PMID: 11756683 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity.

    Air EL, Strowski MZ, Benoit SC, Conarello SL, Salituro GM, Guan XM, Liu K, Woods SC, Zhang BB.

    Nat Med. 2002 Feb;8(2):179-83. Erratum in: Nat Med 2002 Mar;8(3):303. PMID: 11821903 [PubMed - indexed for MEDLINE]Related articles

    16.

    The role of CNS glucagon-like peptide-1 (7-36) amide receptors in mediating the visceral illness effects of lithium chloride.

    Seeley RJ, Blake K, Rushing PA, Benoit S, Eng J, Woods SC, D'Alessio D.

    J Neurosci. 2000 Feb 15;20(4):1616-21.PMID: 10662851 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The anorexigenic fatty acid synthase inhibitor, C75, is a nonspecific neuronal activator.

    Takahashi KA, Smart JL, Liu H, Cone RD.

    Endocrinology. 2004 Jan;145(1):184-93. Epub 2003 Sep 25.PMID: 14512433 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The connections between C75 and obesity drug-target pathways.

    Kuhajda FP, Landree LE, Ronnett GV.

    Trends Pharmacol Sci. 2005 Nov;26(11):541-4. Epub 2005 Sep 16.PMID: 16169094 [PubMed - indexed for MEDLINE]Related articles

    19.

    Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem.

    Gao S, Lane MD.

    Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33. Epub 2003 Apr 30.PMID: 12724522 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Hypothalamic malonyl-CoA as a mediator of feeding behavior.

    Hu Z, Cha SH, Chohnan S, Lane MD.

    Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12624-9. Epub 2003 Oct 7.PMID: 14532332 [PubMed - indexed for MEDLINE]Related articlesFree article

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