PubMed

Role of NADH shuttles in glucose-induced insulin secretion from fetal beta-cells.

Tan C, Tuch BE, Tu J, Brown SA.

Diabetes. 2002 Oct;51(10):2989-96. Erratum in: Diabetes 2003 Jan;52(1):224. PMID: 12351438 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of mitochondrial FAD-linked glycerol-3-phosphate dehydrogenase does not correct glucose-stimulated insulin secretion from diabetic GK rat pancreatic islets.

Ueda K, Tanizawa Y, Ishihara H, Kizuki N, Ohta Y, Matsutani A, Oka Y.

Diabetologia. 1998 Jun;41(6):649-53.PMID: 9662045 [PubMed - indexed for MEDLINE]Related articles

Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells.

Ishihara H, Nakazaki M, Kanegae Y, Inukai K, Asano T, Katagiri H, Yazaki Y, Kikuchi M, Miyazaki J, Saito I, Oka Y.

Diabetes. 1996 Sep;45(9):1238-44.PMID: 8772729 [PubMed - indexed for MEDLINE]Related articles

The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout.

Ravier MA, Eto K, Jonkers FC, Nenquin M, Kadowaki T, Henquin JC.

J Biol Chem. 2000 Jan 21;275(3):1587-93.PMID: 10636849 [PubMed - indexed for MEDLINE]Related articlesFree article

NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion.

Eto K, Suga S, Wakui M, Tsubamoto Y, Terauchi Y, Taka J, Aizawa S, Noda M, Kimura S, Kasai H, Kadowaki T.

J Biol Chem. 1999 Sep 3;274(36):25386-92.PMID: 10464266 [PubMed - indexed for MEDLINE]Related articlesFree article

Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.

Sekine N, Cirulli V, Regazzi R, Brown LJ, Gine E, Tamarit-Rodriguez J, Girotti M, Marie S, MacDonald MJ, Wollheim CB, et al.

J Biol Chem. 1994 Feb 18;269(7):4895-902.PMID: 8106462 [PubMed - indexed for MEDLINE]Related articlesFree article

[Role of the NADH shuttle system in glucose-induced insulin secretion]

Eto K, Kadowaki T.

Nippon Rinsho. 1999 Mar;57(3):503-14. Review. Japanese. PMID: 10199125 [PubMed - indexed for MEDLINE]Related articles

The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.

Rubi B, del Arco A, Bartley C, Satrustegui J, Maechler P.

J Biol Chem. 2004 Dec 31;279(53):55659-66. Epub 2004 Oct 19.PMID: 15494407 [PubMed - indexed for MEDLINE]Related articlesFree article

Survey of normal appearing mouse strain which lacks malic enzyme and Nad+-linked glycerol phosphate dehydrogenase: normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle.

MacDonald MJ, Marshall LK.

Mol Cell Biochem. 2001 Apr;220(1-2):117-25.PMID: 11451371 [PubMed - indexed for MEDLINE]Related articles

Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.

Ainscow EK, Zhao C, Rutter GA.

Diabetes. 2000 Jul;49(7):1149-55.PMID: 10909972 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis.

García-Flores M, Zueco JA, Arenas J, Blázquez E.

Eur J Biochem. 2002 Jan;269(1):119-27.PMID: 11784305 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion.

Eto K, Tsubamoto Y, Terauchi Y, Sugiyama T, Kishimoto T, Takahashi N, Yamauchi N, Kubota N, Murayama S, Aizawa T, Akanuma Y, Aizawa S, Kasai H, Yazaki Y, Kadowaki T.

Science. 1999 Feb 12;283(5404):981-5.PMID: 9974390 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial-encoded gene regulation in rat pancreatic islets.

Lee B, Srinivasan M, Aalinkeel R, Patel MS, Laychock SG.

Metabolism. 2001 Feb;50(2):200-6.PMID: 11229430 [PubMed - indexed for MEDLINE]Related articles

Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.

Takehiro M, Fujimoto S, Shimodahira M, Shimono D, Mukai E, Nabe K, Radu RG, Kominato R, Aramaki Y, Seino Y, Yamada Y.

Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E372-80. Epub 2004 Oct 12.PMID: 15479955 [PubMed - indexed for MEDLINE]Related articlesFree article

Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets.

Gauthier BR, Brun T, Sarret EJ, Ishihara H, Schaad O, Descombes P, Wollheim CB.

J Biol Chem. 2004 Jul 23;279(30):31121-30. Epub 2004 May 19.PMID: 15151993 [PubMed - indexed for MEDLINE]Related articlesFree article

Histochemical evidence for pathways insulin cells use to oxidize glycolysis-derived NADH.

MacDonald MJ, Kelley PC, Laclau M.

Metabolism. 2002 Mar;51(3):318-21.PMID: 11887167 [PubMed - indexed for MEDLINE]Related articles

beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats.

Liu YQ, Jetton TL, Leahy JL.

J Biol Chem. 2002 Oct 18;277(42):39163-8. Epub 2002 Jul 29.PMID: 12147706 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.

Antinozzi PA, Ishihara H, Newgard CB, Wollheim CB.

J Biol Chem. 2002 Apr 5;277(14):11746-55. Epub 2002 Jan 30.PMID: 11821387 [PubMed - indexed for MEDLINE]Related articlesFree article

Pentose phosphate shunt, pyridine nucleotides, glutathione, and insulin secretion of fetal islets.

Ammon HP, Bumiller G, Düppenbecker H, Heinze E, Lutz S, Verspohl EJ.

Am J Physiol. 1983 Apr;244(4):E354-60.PMID: 6340522 [PubMed - indexed for MEDLINE]Related articles

Expression of glucokinase in glucose-unresponsive human fetal pancreatic islet-like cell clusters.

Tu J, Tuch BE.

J Clin Endocrinol Metab. 1997 Mar;82(3):943-8.PMID: 9062511 [PubMed - indexed for MEDLINE]Related articlesFree article