PubMed

Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life.

Löbner K, Steinbrenner H, Roberts GA, Ling Z, Huang GC, Piquer S, Pipeleers DG, Seissler J, Christie MR.

Diabetes. 2002 Oct;51(10):2982-8.PMID: 12351437 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of the protein tyrosine phosphatase-like protein IA-2 during pancreatic islet development.

Roberts C, Roberts GA, Löbner K, Bearzatto M, Clark A, Bonifacio E, Christie MR.

J Histochem Cytochem. 2001 Jun;49(6):767-76.PMID: 11373323 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.

Seissler J, Nguyen TB, Aust G, Steinbrenner H, Scherbaum WA.

Diabetes. 2000 Jul;49(7):1137-41.PMID: 10909970 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.

Torii S, Saito N, Kawano A, Hou N, Ueki K, Kulkarni RN, Takeuchi T.

Diabetes. 2009 Mar;58(3):682-92. Epub 2008 Dec 10.PMID: 19073770 [PubMed - indexed for MEDLINE]Related articlesFree article

IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm.

Zahn TR, Macmorris MA, Dong W, Day R, Hutton JC.

J Comp Neurol. 2001 Jan 1;429(1):127-43.PMID: 11086294 [PubMed - indexed for MEDLINE]Related articles

Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes.

Wasmeier C, Hutton JC.

J Biol Chem. 1996 Jul 26;271(30):18161-70.PMID: 8663434 [PubMed - indexed for MEDLINE]Related articlesFree article

Secretagogue-dependent phosphorylation of phogrin, an insulin granule membrane protein tyrosine phosphatase homologue.

Wasmeier C, Hutton JC.

Biochem J. 1999 Aug 1;341 ( Pt 3):563-9.PMID: 10417318 [PubMed - indexed for MEDLINE]Related articlesFree article

IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.

Doi A, Shono T, Nishi M, Furuta H, Sasaki H, Nanjo K.

Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):885-90. Epub 2006 Jan 17.PMID: 16418280 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

Kubosaki A, Gross S, Miura J, Saeki K, Zhu M, Nakamura S, Hendriks W, Notkins AL.

Diabetes. 2004 Jul;53(7):1684-91.PMID: 15220191 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin secretagogues activate the secretory granule receptor-like protein-tyrosine phosphatase IAR.

Cui L, Yu WP, Pallen CJ.

J Biol Chem. 1998 Dec 25;273(52):34784-91.PMID: 9857003 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of the protein tyrosine phosphatase-like molecule IA-2 results in alterations in glucose tolerance tests and insulin secretion.

Saeki K, Zhu M, Kubosaki A, Xie J, Lan MS, Notkins AL.

Diabetes. 2002 Jun;51(6):1842-50.PMID: 12031972 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting of a phogrin-green fluorescent protein chimaera to insulin secretory granules of pancreatic beta-cells in transgenic mice.

Bright NA, Walters J, Wasmeier C, Hutton JC.

Diabetes Metab. 2002 Dec;28(6 Pt 2):3S29-36; discussion 3S108-12.PMID: 12688631 [PubMed - indexed for MEDLINE]Related articles

The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion.

Harashima S, Clark A, Christie MR, Notkins AL.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8704-9. Epub 2005 Jun 6.PMID: 15939893 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of protein-tyrosine phosphatases stimulates insulin secretion in pancreatic islets of diabetic Goto-Kakizaki rats.

Chen J, Ostenson CG.

Pancreas. 2005 May;30(4):314-7.PMID: 15841039 [PubMed - indexed for MEDLINE]Related articles

Overexpression of protein-tyrosine phosphatase PTP sigma is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats.

Ostenson CG, Sandberg-Nordqvist AC, Chen J, Hällbrink M, Rotin D, Langel U, Efendic S.

Biochem Biophys Res Commun. 2002 Mar 8;291(4):945-50.PMID: 11866457 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

Henquin JC, Nenquin M, Szollosi A, Kubosaki A, Notkins AL.

J Endocrinol. 2008 Mar;196(3):573-81.PMID: 18310453 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of the 37-kDa antigen in IDDM as a tyrosine phosphatase-like protein (phogrin) related to IA-2.

Hawkes CJ, Wasmeier C, Christie MR, Hutton JC.

Diabetes. 1996 Sep;45(9):1187-92.PMID: 8772720 [PubMed - indexed for MEDLINE]Related articles

Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis.

Knoch KP, Bergert H, Borgonovo B, Saeger HD, Altkrüger A, Verkade P, Solimena M.

Nat Cell Biol. 2004 Mar;6(3):207-14. Epub 2004 Feb 22.PMID: 15039777 [PubMed - indexed for MEDLINE]Related articles

Secretory-granule dynamics visualized in vivo with a phogrin-green fluorescent protein chimaera.

Pouli AE, Emmanouilidou E, Zhao C, Wasmeier C, Hutton JC, Rutter GA.

Biochem J. 1998 Jul 1;333 ( Pt 1):193-9.PMID: 9639579 [PubMed - indexed for MEDLINE]Related articlesFree article

Dense core vesicle proteins IA-2 and IA-2beta: metabolic alterations in double knockout mice.

Kubosaki A, Nakamura S, Notkins AL.

Diabetes. 2005 Dec;54 Suppl 2:S46-51.PMID: 16306340 [PubMed - indexed for MEDLINE]Related articlesFree article