PubMed

Thymectomy and radiation-induced type 1 diabetes in nonlymphopenic BB rats.

Ramanathan S, Bihoreau MT, Paterson AD, Marandi L, Gauguier D, Poussier P.

Diabetes. 2002 Oct;51(10):2975-81.PMID: 12351436 [PubMed - indexed for MEDLINE]Related articlesFree article

Kilham rat triggers T-cell-dependent autoimmune diabetes in multiple strains of rat.

Ellerman KE, Richards CA, Guberski DL, Shek WR, Like AA.

Diabetes. 1996 May;45(5):557-62.PMID: 8621003 [PubMed - indexed for MEDLINE]Related articles

Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4.

Martin AM, Maxson MN, Leif J, Mordes JP, Greiner DL, Blankenhorn EP.

Diabetes. 1999 Nov;48(11):2138-44.PMID: 10535446 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripheral autoantigen induces regulatory T cells that prevent autoimmunity.

Seddon B, Mason D.

J Exp Med. 1999 Mar 1;189(5):877-82.PMID: 10049952 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.

MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A.

Genome Res. 2002 Jul;12(7):1029-39.PMID: 12097339 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat.

Martin AM, Blankenhorn EP, Maxson MN, Zhao M, Leif J, Mordes JP, Greiner DL.

Diabetes. 1999 Jan;48(1):50-8.PMID: 9892222 [PubMed - indexed for MEDLINE]Related articlesFree article

DR.lyp/lyp bone marrow maintains lymphopenia and promotes diabetes in lyp/lyp but not in +/+ recipient DR.lyp BB rats.

Hawkins T, Fuller J, Olson K, Speros S, Lernmark A.

J Autoimmun. 2005 Dec;25(4):251-7. Epub 2005 Oct 24.PMID: 16246525 [PubMed - indexed for MEDLINE]Related articles

Quantitative analyses comparing all major spleen cell phenotypes in BB and normal rats: autoimmune imbalance and double negative T cells associated with resistant, prone and diabetic animals.

Hosszufalusi N, Chan E, Granger G, Charles MA.

J Autoimmun. 1992 Jun;5(3):305-18.PMID: 1388637 [PubMed - indexed for MEDLINE]Related articles

Temporary, but essential requirement of CD8+ T cells early in the pathogenesis of diabetes in BB rats as revealed by thymectomy and CD8 depletion.

Groen H, Klatter F, Pater J, Nieuwenhuis P, Rozing J.

Clin Dev Immunol. 2003 Jun-Dec;10(2-4):141-51.PMID: 14768945 [PubMed - indexed for MEDLINE]Related articlesFree article

Excessive production of nitric oxide by macrophages from DP-BB rats is secondary to the T-lymphopenic state of these animals.

Lau A, Ramanathan S, Poussier P.

Diabetes. 1998 Feb;47(2):197-205.PMID: 9519713 [PubMed - indexed for MEDLINE]Related articles

Genetics of the BB rat: association of autoimmune disorders (diabetes, insulitis, and thyroiditis) with lymphopenia and major histocompatibility complex class II.

Awata T, Guberski DL, Like AA.

Endocrinology. 1995 Dec;136(12):5731-5.PMID: 7588330 [PubMed - indexed for MEDLINE]Related articles

A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes.

Wallis RH, Wang K, Dabrowski D, Marandi L, Ning T, Hsieh E, Paterson AD, Mordes JP, Blankenhorn EP, Poussier P.

Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27.PMID: 17389329 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic studies in inbred BB/Wor rats. Analysis of progeny produced by crossing lymphopenic diabetes-prone rats with nonlymphopenic diabetic rats.

Guberski DL, Butler L, Kastern W, Like AA.

Diabetes. 1989 Jul;38(7):887-93.PMID: 2567683 [PubMed - indexed for MEDLINE]Related articles

A major histocompatibility complex class II restriction for BioBreeding/Worcester diabetes-inducing T cells.

Ellerman KE, Like AA.

J Exp Med. 1995 Oct 1;182(4):923-30.PMID: 7561695 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 diabetes mellitus in the BioBreeding rat.

Hessner MJ, Wang X, Meyer L, Geoffrey R, Jia S, Fuller J, Lernmark A, Ghosh S.

J Immunol. 2004 Dec 1;173(11):6993-7002.PMID: 15557196 [PubMed - indexed for MEDLINE]Related articlesFree article

Polygenic nature of spontaneous diabetes in the rat. Permissive MHC haplotype and presence of the lymphopenic trait of the BB rat are not sufficient to produce susceptibility.

Colle E, Fuks A, Poussier P, Edouard P, Guttmann RD.

Diabetes. 1992 Dec;41(12):1617-23.PMID: 1446803 [PubMed - indexed for MEDLINE]Related articles

Deficiencies in gut NK cell number and function precede diabetes onset in BB rats.

Todd DJ, Forsberg EM, Greiner DL, Mordes JP, Rossini AA, Bortell R.

J Immunol. 2004 May 1;172(9):5356-62.PMID: 15100275 [PubMed - indexed for MEDLINE]Related articlesFree article

Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene.

Cousins L, Graham M, Tooze R, Carter C, Miller JR, Powrie FM, Macpherson GG, Butcher GW.

Gastroenterology. 2006 Nov;131(5):1475-85. Epub 2006 Oct 5.PMID: 17064701 [PubMed - indexed for MEDLINE]Related articles

Genetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat.

Moralejo DH, Park HA, Speros SJ, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A.

J Autoimmun. 2003 Dec;21(4):315-24.PMID: 14624755 [PubMed - indexed for MEDLINE]Related articles

T cells from BB-DP rats show a unique cytokine mRNA profile associated with the IDDM1 susceptibility gene, Lyp.

Gold DP, Shaikewitz ST, Mueller D, Redd JR, Sellins KS, Pettersson A, Lernmark A, Bellgrau D.

Autoimmunity. 1995;22(3):149-61.PMID: 8734569 [PubMed - indexed for MEDLINE]Related articles