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    Results: 1 to 20 of 121

    1.

    Metabolic and autocrine regulation of the mammalian target of rapamycin by pancreatic beta-cells.

    McDaniel ML, Marshall CA, Pappan KL, Kwon G.

    Diabetes. 2002 Oct;51(10):2877-85. Review.PMID: 12351422 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Metabolic regulation by leucine of translation initiation through the mTOR-signaling pathway by pancreatic beta-cells.

    Xu G, Kwon G, Cruz WS, Marshall CA, McDaniel ML.

    Diabetes. 2001 Feb;50(2):353-60.PMID: 11272147 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling.

    Xu G, Kwon G, Marshall CA, Lin TA, Lawrence JC Jr, McDaniel ML.

    J Biol Chem. 1998 Oct 23;273(43):28178-84.PMID: 9774438 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.

    Wang X, Beugnet A, Murakami M, Yamanaka S, Proud CG.

    Mol Cell Biol. 2005 Apr;25(7):2558-72.PMID: 15767663 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.

    Fang CX, Yang X, Sreejayan N, Ren J.

    Exp Neurol. 2007 Jan;203(1):196-204. Epub 2006 Sep 7.PMID: 16962100 [PubMed - indexed for MEDLINE]Related articles

    6.

    Signaling elements involved in the metabolic regulation of mTOR by nutrients, incretins, and growth factors in islets.

    Kwon G, Marshall CA, Pappan KL, Remedi MS, McDaniel ML.

    Diabetes. 2004 Dec;53 Suppl 3:S225-32. Review.PMID: 15561916 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Glycogen synthase kinase-3 and mammalian target of rapamycin pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets.

    Liu H, Remedi MS, Pappan KL, Kwon G, Rohatgi N, Marshall CA, McDaniel ML.

    Diabetes. 2009 Mar;58(3):663-72. Epub 2008 Dec 10.PMID: 19073772 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin.

    Kimball SR, Jefferson LS.

    Curr Opin Clin Nutr Metab Care. 2004 Jan;7(1):39-44. Review.PMID: 15090902 [PubMed - indexed for MEDLINE]Related articles

    9.

    The mammalian target of rapamycin pathway and its role in molecular nutrition regulation.

    Lian J, Yan XH, Peng J, Jiang SW.

    Mol Nutr Food Res. 2008 Apr;52(4):393-9. Review.PMID: 18306429 [PubMed - indexed for MEDLINE]Related articles

    10.

    In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.

    Mothe-Satney I, Gautier N, Hinault C, Lawrence JC Jr, Van Obberghen E.

    J Biol Chem. 2004 Oct 8;279(41):42628-37. Epub 2004 Aug 2.PMID: 15292249 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.

    Smith EM, Finn SG, Tee AR, Browne GJ, Proud CG.

    J Biol Chem. 2005 May 13;280(19):18717-27. Epub 2005 Mar 16.PMID: 15772076 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.

    Wang X, Yue P, Chan CB, Ye K, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Fu H, Khuri FR, Sun SY.

    Mol Cell Biol. 2007 Nov;27(21):7405-13. Epub 2007 Aug 27.PMID: 17724079 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Nutrient signalling in the regulation of human muscle protein synthesis.

    Fujita S, Dreyer HC, Drummond MJ, Glynn EL, Cadenas JG, Yoshizawa F, Volpi E, Rasmussen BB.

    J Physiol. 2007 Jul 15;582(Pt 2):813-23. Epub 2007 May 3.PMID: 17478528 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.

    Deshmukh AS, Treebak JT, Long YC, Viollet B, Wojtaszewski JF, Zierath JR.

    Mol Endocrinol. 2008 May;22(5):1105-12. Epub 2008 Feb 14.PMID: 18276828 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.

    Beugnet A, Tee AR, Taylor PM, Proud CG.

    Biochem J. 2003 Jun 1;372(Pt 2):555-66. Erratum in: Biochem J. 2003 Aug 1;373(Pt 3):999. PMID: 12611592 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.

    Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR.

    J Biol Chem. 2005 Jan 21;280(3):1838-48. Epub 2004 Nov 1.PMID: 15522879 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.

    Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS.

    Cancer Res. 2005 Nov 1;65(21):9953-61.PMID: 16267020 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway.

    Han B, Tong J, Zhu MJ, Ma C, Du M.

    Mol Reprod Dev. 2008 May;75(5):810-7.PMID: 18033679 [PubMed - indexed for MEDLINE]Related articles

    19.

    Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.

    Briaud I, Dickson LM, Lingohr MK, McCuaig JF, Lawrence JC, Rhodes CJ.

    J Biol Chem. 2005 Jan 21;280(3):2282-93. Epub 2004 Nov 9.PMID: 15537654 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

    Mieulet V, Roceri M, Espeillac C, Sotiropoulos A, Ohanna M, Oorschot V, Klumperman J, Sandri M, Pende M.

    Am J Physiol Cell Physiol. 2007 Aug;293(2):C712-22. Epub 2007 May 9.PMID: 17494629 [PubMed - indexed for MEDLINE]Related articlesFree article

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