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    Results: 1 to 20 of 221

    1.

    The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.

    Stitt A, Gardiner TA, Alderson NL, Canning P, Frizzell N, Duffy N, Boyle C, Januszewski AS, Chachich M, Baynes JW, Thorpe SR.

    Diabetes. 2002 Sep;51(9):2826-32. Erratum in: Diabetes 2003 Jan;52(1):223. Anderson Nathan L [corrected to Alderson Nathan L]. PMID: 12196477 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats.

    Alderson NL, Chachich ME, Youssef NN, Beattie RJ, Nachtigal M, Thorpe SR, Baynes JW.

    Kidney Int. 2003 Jun;63(6):2123-33.PMID: 12753299 [PubMed - indexed for MEDLINE]Related articles

    3.

    Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications.

    Metz TO, Alderson NL, Thorpe SR, Baynes JW.

    Arch Biochem Biophys. 2003 Nov 1;419(1):41-9. Review.PMID: 14568007 [PubMed - indexed for MEDLINE]Related articles

    4.

    Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes.

    Canning P, Glenn JV, Hsu DK, Liu FT, Gardiner TA, Stitt AW.

    Exp Diabetes Res. 2007;2007:51837.PMID: 17641742 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes.

    Gardiner TA, Anderson HR, Stitt AW.

    J Pathol. 2003 Oct;201(2):328-33.PMID: 14517851 [PubMed - indexed for MEDLINE]Related articles

    6.

    Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat.

    Alderson NL, Chachich ME, Frizzell N, Canning P, Metz TO, Januszewski AS, Youssef NN, Stitt AW, Baynes JW, Thorpe SR.

    Diabetologia. 2004 Aug;47(8):1385-95. Epub 2004 Jul 28.PMID: 15309289 [PubMed - indexed for MEDLINE]Related articles

    7.

    Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia.

    Kern TS, Tang J, Mizutani M, Kowluru RA, Nagaraj RH, Romeo G, Podesta F, Lorenzi M.

    Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3972-8.PMID: 11053301 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Antioxidants and an inhibitor of advanced glycation ameliorate death of retinal microvascular cells in diabetic retinopathy.

    Yatoh S, Mizutani M, Yokoo T, Kozawa T, Sone H, Toyoshima H, Suzuki S, Shimano H, Kawakami Y, Okuda Y, Yamada N.

    Diabetes Metab Res Rev. 2006 Jan-Feb;22(1):38-45.PMID: 15892182 [PubMed - indexed for MEDLINE]Related articles

    9.

    Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine.

    Onorato JM, Jenkins AJ, Thorpe SR, Baynes JW.

    J Biol Chem. 2000 Jul 14;275(28):21177-84.PMID: 10801874 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats.

    Rota R, Chiavaroli C, Garay RP, Hannaert P.

    Eur J Pharmacol. 2004 Jul 14;495(2-3):217-24.PMID: 15249173 [PubMed - indexed for MEDLINE]Related articles

    11.

    A new advanced glycation inhibitor, LR-90, prevents experimental diabetic retinopathy in rats.

    Bhatwadekar A, Glenn JV, Figarola JL, Scott S, Gardiner TA, Rahbar S, Stitt AW.

    Br J Ophthalmol. 2008 Apr;92(4):545-7. Epub 2008 Jan 22.PMID: 18211931 [PubMed - indexed for MEDLINE]Related articles

    12.

    Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.

    de Gooyer TE, Stevenson KA, Humphries P, Simpson DA, Gardiner TA, Stitt AW.

    Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5561-8.PMID: 17122149 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Angiotensin II receptor blocker inhibits abnormal accumulation of advanced glycation end products and retinal damage in a rat model of type 2 diabetes.

    Sugiyama T, Okuno T, Fukuhara M, Oku H, Ikeda T, Obayashi H, Ohta M, Fukui M, Hasegawa G, Nakamura N.

    Exp Eye Res. 2007 Sep;85(3):406-12. Epub 2007 Jun 19.PMID: 17678894 [PubMed - indexed for MEDLINE]Related articles

    14.

    Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina.

    Hughes JM, Kuiper EJ, Klaassen I, Canning P, Stitt AW, Van Bezu J, Schalkwijk CG, Van Noorden CJ, Schlingemann RO.

    Diabetologia. 2007 May;50(5):1089-98. Epub 2007 Feb 28.PMID: 17333105 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.

    Degenhardt TP, Alderson NL, Arrington DD, Beattie RJ, Basgen JM, Steffes MW, Thorpe SR, Baynes JW.

    Kidney Int. 2002 Mar;61(3):939-50.PMID: 11849448 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats.

    Stitt AW, Li YM, Gardiner TA, Bucala R, Archer DB, Vlassara H.

    Am J Pathol. 1997 Feb;150(2):523-31.PMID: 9033268 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.

    Reber F, Geffarth R, Kasper M, Reichenbach A, Schleicher ED, Siegner A, Funk RH.

    Graefes Arch Clin Exp Ophthalmol. 2003 Mar;241(3):213-25. Epub 2003 Feb 7.PMID: 12644946 [PubMed - indexed for MEDLINE]Related articles

    18.

    Pyridoxamine inhibits maillard reactions in diabetic rat lenses.

    Padival S, Nagaraj RH.

    Ophthalmic Res. 2006;38(5):294-302. Epub 2006 Sep 15.PMID: 16974131 [PubMed - indexed for MEDLINE]Related articles

    20.

    Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.

    Tanimoto M, Gohda T, Kaneko S, Hagiwara S, Murakoshi M, Aoki T, Yamada K, Ito T, Matsumoto M, Horikoshi S, Tomino Y.

    Metabolism. 2007 Feb;56(2):160-7.PMID: 17224327 [PubMed - indexed for MEDLINE]Related articles

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