PubMed

Diacylglycerol production and protein kinase C activity are increased in a mouse model of diabetic embryopathy.

Hiramatsu Y, Sekiguchi N, Hayashi M, Isshiki K, Yokota T, King GL, Loeken MR.

Diabetes. 2002 Sep;51(9):2804-10.PMID: 12196474 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of protein kinase c-delta and c-epsilon by oxidative stress in early diabetic rat kidney.

Ha H, Yu MR, Choi YJ, Lee HB.

Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S204-7.PMID: 11576956 [PubMed - indexed for MEDLINE]Related articles

Requirement of aldose reductase for the hyperglycemic activation of protein kinase C and formation of diacylglycerol in vascular smooth muscle cells.

Ramana KV, Friedrich B, Tammali R, West MB, Bhatnagar A, Srivastava SK.

Diabetes. 2005 Mar;54(3):818-29.PMID: 15734861 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.

Bursell SE, Takagi C, Clermont AC, Takagi H, Mori F, Ishii H, King GL.

Invest Ophthalmol Vis Sci. 1997 Dec;38(13):2711-20.PMID: 9418723 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol.

Koya D, Lee IK, Ishii H, Kanoh H, King GL.

J Am Soc Nephrol. 1997 Mar;8(3):426-35.PMID: 9071711 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of protein kinase C activation and the vascular complications of diabetes.

Das Evcimen N, King GL.

Pharmacol Res. 2007 Jun;55(6):498-510. Epub 2007 May 5. Review.PMID: 17574431 [PubMed - indexed for MEDLINE]Related articles

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation.

Inoguchi T, Battan R, Handler E, Sportsman JR, Heath W, King GL.

Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):11059-63.PMID: 1438315 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered protein kinase C activation associated with rat embryonic dysmorphogenesis.

Gäreskog M, Wentzel P.

Pediatr Res. 2004 Dec;56(6):849-57. Epub 2004 Oct 20.PMID: 15496608 [PubMed - indexed for MEDLINE]Related articles

Prevention of diabetes-induced abnormal retinal blood flow by treatment with d-alpha-tocopherol.

Kunisaki M, Bursell SE, Umeda F, Nawata H, King GL.

Biofactors. 1998;7(1-2):55-67.PMID: 9523029 [PubMed - indexed for MEDLINE]Related articles

Vitamin E normalizes diacylglycerol-protein kinase C activation induced by hyperglycemia in rat vascular tissues.

Kunisaki M, Fumio U, Nawata H, King GL.

Diabetes. 1996 Jul;45 Suppl 3:S117-9.PMID: 8674876 [PubMed - indexed for MEDLINE]Related articles

Normalization of diacylglycerol-protein kinase C activation by vitamin E in aorta of diabetic rats and cultured rat smooth muscle cells exposed to elevated glucose levels.

Kunisaki M, Bursell SE, Umeda F, Nawata H, King GL.

Diabetes. 1994 Nov;43(11):1372-7.PMID: 7926314 [PubMed - indexed for MEDLINE]Related articles

Diabetes mellitus affects prostaglandin E2 levels in mouse embryos during neurulation.

Piddington R, Joyce J, Dhanasekaran P, Baker L.

Diabetologia. 1996 Aug;39(8):915-20.PMID: 8858213 [PubMed - indexed for MEDLINE]Related articles

Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy.

Yang P, Zhao Z, Reece EA.

Am J Obstet Gynecol. 2008 Jan;198(1):130.e1-7.PMID: 18166327 [PubMed - indexed for MEDLINE]Related articles

Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation.

Shiba T, Inoguchi T, Sportsman JR, Heath WF, Bursell S, King GL.

Am J Physiol. 1993 Nov;265(5 Pt 1):E783-93.PMID: 8238505 [PubMed - indexed for MEDLINE]Related articles

Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.

Fine EL, Horal M, Chang TI, Fortin G, Loeken MR.

Diabetes. 1999 Dec;48(12):2454-62.PMID: 10580436 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues.

Inoguchi T, Xia P, Kunisaki M, Higashi S, Feener EP, King GL.

Am J Physiol. 1994 Sep;267(3 Pt 1):E369-79.PMID: 7943217 [PubMed - indexed for MEDLINE]Related articles

Protein kinase C activation and the development of diabetic complications.

Koya D, King GL.

Diabetes. 1998 Jun;47(6):859-66. Review.PMID: 9604860 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoxic stress in diabetic pregnancy contributes to impaired embryo gene expression and defective development by inducing oxidative stress.

Li R, Chase M, Jung SK, Smith PJ, Loeken MR.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E591-9. Epub 2005 May 31.PMID: 15928021 [PubMed - indexed for MEDLINE]Related articlesFree article

Vitamin E prevents diabetes-induced abnormal retinal blood flow via the diacylglycerol-protein kinase C pathway.

Kunisaki M, Bursell SE, Clermont AC, Ishii H, Ballas LM, Jirousek MR, Umeda F, Nawata H, King GL.

Am J Physiol. 1995 Aug;269(2 Pt 1):E239-46.PMID: 7653541 [PubMed - indexed for MEDLINE]Related articles

N-Acetylcysteine and alpha-cyano-4-hydroxycinnamic acid alter protein kinase C (PKC)-delta and PKC-zeta and diminish dysmorphogenesis in rat embryos cultured with high glucose in vitro.

Gäreskog M, Wentzel P.

J Endocrinol. 2007 Jan;192(1):207-14.PMID: 17210758 [PubMed - indexed for MEDLINE]Related articlesFree article