PubMed

Expression of connective tissue growth factor is increased in injured myocardium associated with protein kinase C beta2 activation and diabetes.

Way KJ, Isshiki K, Suzuma K, Yokota T, Zvagelsky D, Schoen FJ, Sandusky GE, Pechous PA, Vlahos CJ, Wakasaki H, King GL.

Diabetes. 2002 Sep;51(9):2709-18.PMID: 12196463 [PubMed - indexed for MEDLINE]Related articlesFree article

CTGF expression is induced by TGF- beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis.

Chen MM, Lam A, Abraham JA, Schreiner GF, Joly AH.

J Mol Cell Cardiol. 2000 Oct;32(10):1805-19.PMID: 11013125 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of angiotensin II-induced expression of connective tissue growth factor by protein kinase C isoforms in the myocardium.

He Z, Way KJ, Arikawa E, Chou E, Opland DM, Clermont A, Isshiki K, Ma RC, Scott JA, Schoen FJ, Feener EP, King GL.

J Biol Chem. 2005 Apr 22;280(16):15719-26. Epub 2005 Feb 7.PMID: 15699040 [PubMed - indexed for MEDLINE]Related articlesFree article

N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats.

Xia Z, Kuo KH, Nagareddy PR, Wang F, Guo Z, Guo T, Jiang J, McNeill JH.

Cardiovasc Res. 2007 Mar 1;73(4):770-82. Epub 2006 Nov 30.PMID: 17250813 [PubMed - indexed for MEDLINE]Related articlesFree article

Advanced glycation end-products induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway.

Zhou G, Li C, Cai L.

Am J Pathol. 2004 Dec;165(6):2033-43.PMID: 15579446 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased connective tissue growth factor relative to brain natriuretic peptide as a determinant of myocardial fibrosis.

Koitabashi N, Arai M, Kogure S, Niwano K, Watanabe A, Aoki Y, Maeno T, Nishida T, Kubota S, Takigawa M, Kurabayashi M.

Hypertension. 2007 May;49(5):1120-7. Epub 2007 Mar 19.PMID: 17372041 [PubMed - indexed for MEDLINE]Related articlesFree article

Connective tissue growth factor and cardiac fibrosis after myocardial infarction.

Dean RG, Balding LC, Candido R, Burns WC, Cao Z, Twigg SM, Burrell LM.

J Histochem Cytochem. 2005 Oct;53(10):1245-56. Epub 2005 Jun 13.PMID: 15956033 [PubMed - indexed for MEDLINE]Related articlesFree article

Connective tissue growth factor causes persistent proalpha2(I) collagen gene expression induced by transforming growth factor-beta in a mouse fibrosis model.

Chujo S, Shirasaki F, Kawara S, Inagaki Y, Kinbara T, Inaoki M, Takigawa M, Takehara K.

J Cell Physiol. 2005 May;203(2):447-56.PMID: 15605379 [PubMed - indexed for MEDLINE]Related articles

Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction.

Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL.

Dev Dyn. 2004 Nov;231(3):542-50.PMID: 15376321 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanisms through which bradykinin promotes glomerular injury in diabetes.

Tan Y, Wang B, Keum JS, Jaffa AA.

Am J Physiol Renal Physiol. 2005 Mar;288(3):F483-92.PMID: 15692059 [PubMed - indexed for MEDLINE]Related articlesFree article

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.

Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S.

Hepatology. 2007 Oct;46(4):1257-70.PMID: 17657819 [PubMed - indexed for MEDLINE]Related articles

Connective tissue growth factor and its regulation: a new element in diabetic glomerulosclerosis.

Riser BL, Cortes P.

Ren Fail. 2001 May-Jul;23(3-4):459-70.PMID: 11499561 [PubMed - indexed for MEDLINE]Related articles

Inactivation of 14-3-3 protein exacerbates cardiac hypertrophy and fibrosis through enhanced expression of protein kinase C beta 2 in experimental diabetes.

Gurusamy N, Watanabe K, Ma M, Zhang S, Muslin AJ, Kodama M, Aizawa Y.

Biol Pharm Bull. 2005 Jun;28(6):957-62.PMID: 15930726 [PubMed - indexed for MEDLINE]Related articlesFree article

Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice.

Roestenberg P, van Nieuwenhoven FA, Joles JA, Trischberger C, Martens PP, Oliver N, Aten J, Höppener JW, Goldschmeding R.

Am J Physiol Renal Physiol. 2006 Jun;290(6):F1344-54. Epub 2005 Dec 27.PMID: 16380465 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of myocardial connective tissue growth factor in pacing-induced heart failure in pigs.

Ahmed MS, von Lueder TG, Øie E, Kjekshus H, Attramadal H.

Acta Physiol Scand. 2005 May;184(1):27-36.PMID: 15847641 [PubMed - indexed for MEDLINE]Related articles

Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy.

Connelly KA, Kelly DJ, Zhang Y, Prior DL, Advani A, Cox AJ, Thai K, Krum H, Gilbert RE.

Circ Heart Fail. 2009 Mar;2(2):129-37. Epub 2009 Feb 10.PMID: 19808328 [PubMed - indexed for MEDLINE]Related articles

Increased expression of connective tissue growth factor in the infarct zone of experimentally induced myocardial infarction in rats.

Ohnishi H, Oka T, Kusachi S, Nakanishi T, Takeda K, Nakahama M, Doi M, Murakami T, Ninomiya Y, Takigawa M, Tsuji T.

J Mol Cell Cardiol. 1998 Nov;30(11):2411-22.PMID: 9925376 [PubMed - indexed for MEDLINE]Related articles

Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein-related protein 2) in human fibroblasts: a potential mechanism for expansion of extracellular matrix in diabetes mellitus.

Twigg SM, Chen MM, Joly AH, Chakrapani SD, Tsubaki J, Kim HS, Oh Y, Rosenfeld RG.

Endocrinology. 2001 May;142(5):1760-9.PMID: 11316739 [PubMed - indexed for MEDLINE]Related articlesFree article

Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model.

Mori T, Kawara S, Shinozaki M, Hayashi N, Kakinuma T, Igarashi A, Takigawa M, Nakanishi T, Takehara K.

J Cell Physiol. 1999 Oct;181(1):153-9.PMID: 10457363 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress triggers cardiac fibrosis in the heart of diabetic rats.

Aragno M, Mastrocola R, Alloatti G, Vercellinatto I, Bardini P, Geuna S, Catalano MG, Danni O, Boccuzzi G.

Endocrinology. 2008 Jan;149(1):380-8. Epub 2007 Sep 27.PMID: 17901230 [PubMed - indexed for MEDLINE]Related articlesFree article