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    Results: 1 to 20 of 345

    1.

    Troglitazone treatment increases protein kinase B phosphorylation in skeletal muscle of normoglycemic subjects at risk for the development of type 2 diabetes.

    Meyer MM, Levin K, Grimmsmann T, Perwitz N, Eirich A, Beck-Nielsen H, Klein HH.

    Diabetes. 2002 Sep;51(9):2691-7.PMID: 12196460 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110beta protein levels in skeletal muscle of type 2 diabetic subjects.

    Kim YB, Ciaraldi TP, Kong A, Kim D, Chu N, Mohideen P, Mudaliar S, Henry RR, Kahn BB.

    Diabetes. 2002 Feb;51(2):443-8.PMID: 11812753 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Effects of troglitazone on cellular differentiation, insulin signaling, and glucose metabolism in cultured human skeletal muscle cells.

    Kausch C, Krützfeldt J, Witke A, Rettig A, Bachmann O, Rett K, Matthaei S, Machicao F, Häring HU, Stumvoll M.

    Biochem Biophys Res Commun. 2001 Jan 26;280(3):664-74.PMID: 11162573 [PubMed - indexed for MEDLINE]Related articles

    4.

    Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.

    Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM.

    J Clin Endocrinol Metab. 2002 Jan;87(1):226-34.PMID: 11788651 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.

    Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB.

    Diabetes. 1999 Feb;48(2):310-20.PMID: 10334307 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.

    Beeson M, Sajan MP, Dizon M, Grebenev D, Gomez-Daspet J, Miura A, Kanoh Y, Powe J, Bandyopadhyay G, Standaert ML, Farese RV.

    Diabetes. 2003 Aug;52(8):1926-34.PMID: 12882907 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

    Storgaard H, Song XM, Jensen CB, Madsbad S, Björnholm M, Vaag A, Zierath JR.

    Diabetes. 2001 Dec;50(12):2770-8. Erratum in: Diabetes 2002 Feb;51(2):552. PMID: 11723060 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise.

    Thong FS, Derave W, Kiens B, Graham TE, Ursø B, Wojtaszewski JF, Hansen BF, Richter EA.

    Diabetes. 2002 Mar;51(3):583-90.PMID: 11872654 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.

    Karlsson HK, Hällsten K, Björnholm M, Tsuchida H, Chibalin AV, Virtanen KA, Heinonen OJ, Lönnqvist F, Nuutila P, Zierath JR.

    Diabetes. 2005 May;54(5):1459-67.PMID: 15855334 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats.

    Kanoh Y, Bandyopadhyay G, Sajan MP, Standaert ML, Farese RV.

    Endocrinology. 2001 Apr;142(4):1595-605.PMID: 11250941 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.

    Miyazaki Y, He H, Mandarino LJ, DeFronzo RA.

    Diabetes. 2003 Aug;52(8):1943-50.PMID: 12882909 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.

    Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA.

    J Clin Endocrinol Metab. 2004 Mar;89(3):1301-11.PMID: 15001626 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Delays in insulin signaling towards glucose disposal in human skeletal muscle.

    Grimmsmann T, Levin K, Meyer MM, Beck-Nielsen H, Klein HH.

    J Endocrinol. 2002 Mar;172(3):645-51.PMID: 11874713 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle.

    Temofonte N, Sajan MP, Nimal S, Pastoor T, Fumero C, Casaubon L, Powe JL, Standaert ML, Farese RV.

    Diabetologia. 2009 Jan;52(1):60-4. Epub 2008 Oct 30.PMID: 18972094 [PubMed - indexed for MEDLINE]Related articles

    15.

    Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

    Ogihara T, Asano T, Ando K, Chiba Y, Sekine N, Sakoda H, Anai M, Onishi Y, Fujishiro M, Ono H, Shojima N, Inukai K, Fukushima Y, Kikuchi M, Fujita T.

    Diabetes. 2001 Mar;50(3):573-83.PMID: 11246877 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Effects of troglitazone in young first-degree relatives of patients with type 2 diabetes.

    Levin K, Hother-Nielsen O, Henriksen JE, Beck-Nielsen H.

    Diabetes Care. 2004 Jan;27(1):148-54.PMID: 14693981 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes.

    Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB.

    J Clin Invest. 1999 Sep;104(6):733-41.PMID: 10491408 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.

    Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB.

    Diabetes. 2003 Aug;52(8):1935-42.PMID: 12882908 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin signalling in skeletal muscle of subjects with or without Type II-diabetes and first degree relatives of patients with the disease.

    Meyer MM, Levin K, Grimmsmann T, Beck-Nielsen H, Klein HH.

    Diabetologia. 2002 Jun;45(6):813-22. Epub 2002 May 8.PMID: 12107725 [PubMed - indexed for MEDLINE]Related articles

    20.

    Troglitazone inhibits mitogenic signaling by insulin in vascular smooth muscle cells.

    Goetze S, Kim S, Xi XP, Graf K, Yang DC, Fleck E, Meehan WP, Hsueh WA, Law RE.

    J Cardiovasc Pharmacol. 2000 May;35(5):749-57.PMID: 10813377 [PubMed - indexed for MEDLINE]Related articles

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