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The succinate mechanism of insulin release.

Fahien LA, MacDonald MJ.

Diabetes. 2002 Sep;51(9):2669-76. Review.PMID: 12196457 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin release by factors that also modify glutamate dehydrogenase.

Fahien LA, MacDonald MJ, Kmiotek EH, Mertz RJ, Fahien CM.

J Biol Chem. 1988 Sep 25;263(27):13610-4.PMID: 3047128 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis.

MacDonald MJ.

Am J Physiol Endocrinol Metab. 2002 Aug;283(2):E302-10.PMID: 12110535 [PubMed - indexed for MEDLINE]Related articlesFree article

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion.

MacDonald MJ.

J Biol Chem. 1995 Aug 25;270(34):20051-8. Erratum in: J Biol Chem 1996 Mar 1;271(9):5287. PMID: 7650022 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolism of the insulin secretagogue methyl succinate by pancreatic islets.

MacDonald MJ.

Arch Biochem Biophys. 1993 Jan;300(1):201-5.PMID: 8424653 [PubMed - indexed for MEDLINE]Related articles

Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell.

MacDonald MJ, Smith AD 3rd, Hasan NM, Sabat G, Fahien LA.

J Biol Chem. 2007 Oct 19;282(42):30596-606. Epub 2007 Aug 27.PMID: 17724028 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell mitochondria: implications in the beta-cell high-energy phosphate metabolism in relation to physiological insulin secretion.

Kowluru A.

Diabetologia. 2001 Jan;44(1):89-94.PMID: 11206416 [PubMed - indexed for MEDLINE]Related articles

Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion.

MacDonald MJ, Longacre MJ, Stoker SW, Brown LJ, Hasan NM, Kendrick MA.

Am J Physiol Cell Physiol. 2008 Feb;294(2):C442-50. Epub 2007 Dec 26.PMID: 18160486 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic potent insulin release by combinations of weak secretagogues in pancreatic islets and INS-1 cells.

MacDonald MJ.

J Biol Chem. 2007 Mar 2;282(9):6043-52. Epub 2007 Jan 8.PMID: 17210580 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of malate dehydrogenase activity by glutamate, citrate, alpha-ketoglutarate, and multienzyme interaction.

Fahien LA, Kmiotek EH, MacDonald MJ, Fibich B, Mandic M.

J Biol Chem. 1988 Aug 5;263(22):10687-97.PMID: 2899080 [PubMed - indexed for MEDLINE]Related articlesFree article

Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.

MacDonald MJ, Fahien LA, Brown LJ, Hasan NM, Buss JD, Kendrick MA.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E1-15. Review.PMID: 15585595 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between the alpha-ketoglutarate dehydrogenase complex and succinate thiokinase.

Porpáczy Z, Sümegi B, Alkonyi I.

Biochim Biophys Acta. 1983 Dec 12;749(2):172-9.PMID: 6652097 [PubMed - indexed for MEDLINE]Related articles

Effect of aspartate on complexes between glutamate dehydrogenase and various aminotransferases.

Fahien LA, Hsu SL, Kmiotek E.

J Biol Chem. 1977 Feb 25;252(4):1250-6.PMID: 14147 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased rate of ketone-body oxidation and decreased activity of D-3-hydroxybutyrate dehydrogenase and succinyl-CoA:3-oxo-acid CoA-transferase in heart mitochondria of diabetic rats.

Grinblat L, Pacheco Bolaños LF, Stoppani AO.

Biochem J. 1986 Nov 15;240(1):49-56.PMID: 3548709 [PubMed - indexed for MEDLINE]Related articlesFree article

Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level.

Peffley DM, Gayen AK.

J Nutr. 2003 Jan;133(1):38-44.PMID: 12514264 [PubMed - indexed for MEDLINE]Related articlesFree article

Hydroxymethylglutaryl coenzyme A reductase activity of adult Hymenolepis diminuta.

Fioravanti CF, Kim Y, Batten CL, Weaver JR.

J Parasitol. 1989 Oct;75(5):653-7.PMID: 2795368 [PubMed - indexed for MEDLINE]Related articles

Metabolic pathways for cytotoxic end product formation from glutamate- and aspartate-containing peptides by Porphyromonas gingivalis.

Takahashi N, Sato T, Yamada T.

J Bacteriol. 2000 Sep;182(17):4704-10.PMID: 10940008 [PubMed - indexed for MEDLINE]Related articlesFree article

The export of metabolites from mitochondria and anaplerosis in insulin secretion.

MacDonald MJ.

Biochim Biophys Acta. 2003 Jan 2;1619(1):77-88.PMID: 12495818 [PubMed - indexed for MEDLINE]Related articles

Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.

Mo H, Elson CE.

Exp Biol Med (Maywood). 2004 Jul;229(7):567-85. Review.PMID: 15229351 [PubMed - indexed for MEDLINE]Related articlesFree article

[The NMR study of succinate formation from exogenous precursors in anaerobic rat heart mitochondria]

Pisarenko OI, Khlopkov VN, Rugge EK.

Biokhimiia. 1986 Jul;51(7):1174-9. Russian. PMID: 3730449 [PubMed - indexed for MEDLINE]Related articles