PubMed

The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.

Lu L, Schulz H, Wolf DA.

BMC Cell Biol. 2002 Aug 20;3:22. Epub 2002 Aug 20.PMID: 12188931 [PubMed - indexed for MEDLINE]Related articlesFree article

Down-regulation of Skp2 is correlated with p27-associated cell cycle arrest induced by phenylacetate in human prostate cancer cells.

Shibahara T, Onishi T, Franco OE, Arima K, Sugimura Y.

Anticancer Res. 2005 May-Jun;25(3B):1881-8.PMID: 16158921 [PubMed - indexed for MEDLINE]Related articles

p27(Kip1) stabilization and G(1) arrest by 1,25-dihydroxyvitamin D(3) in ovarian cancer cells mediated through down-regulation of cyclin E/cyclin-dependent kinase 2 and Skp1-Cullin-F-box protein/Skp2 ubiquitin ligase.

Li P, Li C, Zhao X, Zhang X, Nicosia SV, Bai W.

J Biol Chem. 2004 Jun 11;279(24):25260-7. Epub 2004 Apr 9.PMID: 15075339 [PubMed - indexed for MEDLINE]Related articlesFree article

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).

Mamillapalli R, Gavrilova N, Mihaylova VT, Tsvetkov LM, Wu H, Zhang H, Sun H.

Curr Biol. 2001 Feb 20;11(4):263-7.PMID: 11250155 [PubMed - indexed for MEDLINE]Related articles

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.

Koga H, Harada M, Ohtsubo M, Shishido S, Kumemura H, Hanada S, Taniguchi E, Yamashita K, Kumashiro R, Ueno T, Sata M.

Hepatology. 2003 May;37(5):1086-96.PMID: 12717389 [PubMed - indexed for MEDLINE]Related articles

Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm.

Yang ES, Burnstein KL.

J Biol Chem. 2003 Nov 21;278(47):46862-8. Epub 2003 Sep 3.PMID: 12954644 [PubMed - indexed for MEDLINE]Related articlesFree article

Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest.

Kokontis JM, Hay N, Liao S.

Mol Endocrinol. 1998 Jul;12(7):941-53.PMID: 9658399 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.

Yang G, Ayala G, De Marzo A, Tian W, Frolov A, Wheeler TM, Thompson TC, Harper JW.

Clin Cancer Res. 2002 Nov;8(11):3419-26.PMID: 12429629 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.

Lin R, Wang TT, Miller WH Jr, White JH.

Endocrinology. 2003 Mar;144(3):749-53.PMID: 12586749 [PubMed - indexed for MEDLINE]Related articlesFree article

Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer.

Ben-Izhak O, Lahav-Baratz S, Meretyk S, Ben-Eliezer S, Sabo E, Dirnfeld M, Cohen S, Ciechanover A.

J Urol. 2003 Jul;170(1):241-5.PMID: 12796697 [PubMed - indexed for MEDLINE]Related articles

Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression.

Carrano AC, Pagano M.

J Cell Biol. 2001 Jun 25;153(7):1381-90.PMID: 11425869 [PubMed - indexed for MEDLINE]Related articlesFree article

Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27.

Waltregny D, Leav I, Signoretti S, Soung P, Lin D, Merk F, Adams JY, Bhattacharya N, Cirenei N, Loda M.

Mol Endocrinol. 2001 May;15(5):765-82.PMID: 11328857 [PubMed - indexed for MEDLINE]Related articlesFree article

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

Wang W, Ungermannova D, Jin J, Harper JW, Liu X.

Oncogene. 2004 Feb 5;23(5):1064-75.PMID: 14676846 [PubMed - indexed for MEDLINE]Related articles

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway.

Hara T, Kamura T, Nakayama K, Oshikawa K, Hatakeyama S, Nakayama K.

J Biol Chem. 2001 Dec 28;276(52):48937-43. Epub 2001 Oct 26.PMID: 11682478 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells.

Gupta S, Hussain T, Mukhtar H.

Arch Biochem Biophys. 2003 Feb 1;410(1):177-85.PMID: 12559991 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells.

Lu Y, Zi X, Pollak M.

Int J Cancer. 2004 Jan 20;108(3):334-41.PMID: 14648698 [PubMed - indexed for MEDLINE]Related articles

Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway.

Foster JS, Fernando RI, Ishida N, Nakayama KI, Wimalasena J.

J Biol Chem. 2003 Oct 17;278(42):41355-66. Epub 2003 Aug 6.PMID: 12904306 [PubMed - indexed for MEDLINE]Related articlesFree article

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.

Rosner M, Hengstschläger M.

J Biol Chem. 2004 Nov 19;279(47):48707-15. Epub 2004 Sep 8.PMID: 15355997 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip).

Chen WJ, Chang CY, Lin JK.

Biochem Pharmacol. 2003 Jun 1;65(11):1777-85.PMID: 12781329 [PubMed - indexed for MEDLINE]Related articles

Expression of the F-box protein SKP2 induces hyperplasia, dysplasia, and low-grade carcinoma in the mouse prostate.

Shim EH, Johnson L, Noh HL, Kim YJ, Sun H, Zeiss C, Zhang H.

Cancer Res. 2003 Apr 1;63(7):1583-8.PMID: 12670908 [PubMed - indexed for MEDLINE]Related articlesFree article