PubMed

Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.

Lee CS, Sund NJ, Vatamaniuk MZ, Matschinsky FM, Stoffers DA, Kaestner KH.

Diabetes. 2002 Aug;51(8):2546-51.PMID: 12145169 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxa2 regulates multiple pathways of insulin secretion.

Lantz KA, Vatamaniuk MZ, Brestelli JE, Friedman JR, Matschinsky FM, Kaestner KH.

J Clin Invest. 2004 Aug;114(4):512-20.PMID: 15314688 [PubMed - indexed for MEDLINE]Related articlesFree article

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48.PMID: 19141476 [PubMed - indexed for MEDLINE]Related articlesFree article

The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas.

Rausa F, Samadani U, Ye H, Lim L, Fletcher CF, Jenkins NA, Copeland NG, Costa RH.

Dev Biol. 1997 Dec 15;192(2):228-46.PMID: 9441664 [PubMed - indexed for MEDLINE]Related articles

The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.

Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA.

J Clin Invest. 2009 Jul;119(7):1888-98.PMID: 19487809 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.

Wu KL, Gannon M, Peshavaria M, Offield MF, Henderson E, Ray M, Marks A, Gamer LW, Wright CV, Stein R.

Mol Cell Biol. 1997 Oct;17(10):6002-13.PMID: 9315659 [PubMed - indexed for MEDLINE]Related articlesFree article

A pancreatic beta -cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta ), HNF-1alpha, and SPs transcription factors.

Ben-Shushan E, Marshak S, Shoshkes M, Cerasi E, Melloul D.

J Biol Chem. 2001 May 18;276(20):17533-40. Epub 2001 Feb 5.PMID: 11278466 [PubMed - indexed for MEDLINE]Related articlesFree article

Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

Foxa2 is required for the differentiation of pancreatic alpha-cells.

Lee CS, Sund NJ, Behr R, Herrera PL, Kaestner KH.

Dev Biol. 2005 Feb 15;278(2):484-95.PMID: 15680365 [PubMed - indexed for MEDLINE]Related articles

Association between hepatocyte nuclear factor 6 (HNF-6) and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding.

Rausa FM, Tan Y, Costa RH.

Mol Cell Biol. 2003 Jan;23(2):437-49.PMID: 12509444 [PubMed - indexed for MEDLINE]Related articlesFree article

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.

Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH 3rd, Wright CV, White MF, Arden KC, Accili D.

J Clin Invest. 2002 Dec;110(12):1839-47.PMID: 12488434 [PubMed - indexed for MEDLINE]Related articlesFree article

Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6.

Samaras SE, Cissell MA, Gerrish K, Wright CV, Gannon M, Stein R.

Mol Cell Biol. 2002 Jul;22(13):4702-13.PMID: 12052878 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of overexpression of Pdx1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells.

Lavon N, Yanuka O, Benvenisty N.

Stem Cells. 2006 Aug;24(8):1923-30. Epub 2006 May 4.PMID: 16675598 [PubMed - indexed for MEDLINE]Related articlesFree article

Conserved transcriptional regulatory domains of the pdx-1 gene.

Gerrish K, Van Velkinburgh JC, Stein R.

Mol Endocrinol. 2004 Mar;18(3):533-48. Epub 2003 Dec 30.PMID: 14701942 [PubMed - indexed for MEDLINE]Related articlesFree article

Winged-helix transcription factors and pancreatic development.

Lantz KA, Kaestner KH.

Clin Sci (Lond). 2005 Mar;108(3):195-204. Review.PMID: 15631623 [PubMed - indexed for MEDLINE]Related articles

Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release.

Wang H, Gauthier BR, Hagenfeldt-Johansson KA, Iezzi M, Wollheim CB.

J Biol Chem. 2002 May 17;277(20):17564-70. Epub 2002 Mar 1.PMID: 11875061 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional conservation of regulatory elements in the pdx-1 gene: PDX-1 and hepatocyte nuclear factor 3beta transcription factors mediate beta-cell-specific expression.

Marshak S, Benshushan E, Shoshkes M, Havin L, Cerasi E, Melloul D.

Mol Cell Biol. 2000 Oct;20(20):7583-90.PMID: 11003654 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia.

Sund NJ, Vatamaniuk MZ, Casey M, Ang SL, Magnuson MA, Stoffers DA, Matschinsky FM, Kaestner KH.

Genes Dev. 2001 Jul 1;15(13):1706-15.PMID: 11445544 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites.

Gerrish K, Gannon M, Shih D, Henderson E, Stoffel M, Wright CV, Stein R.

J Biol Chem. 2000 Feb 4;275(5):3485-92.PMID: 10652343 [PubMed - indexed for MEDLINE]Related articlesFree article

A transcription factor regulatory circuit in differentiated pancreatic cells.

Boj SF, Parrizas M, Maestro MA, Ferrer J.

Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14481-6. Epub 2001 Nov 20.PMID: 11717395 [PubMed - indexed for MEDLINE]Related articlesFree article