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    Results: 1 to 20 of 309

    1.

    Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice.

    Hori H, Sasaoka T, Ishihara H, Wada T, Murakami S, Ishiki M, Kobayashi M.

    Diabetes. 2002 Aug;51(8):2387-94.PMID: 12145149 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

    Shao J, Yamashita H, Qiao L, Friedman JE.

    J Endocrinol. 2000 Oct;167(1):107-15.PMID: 11018758 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.

    Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.

    Mol Cell Biol. 2001 Mar;21(5):1633-46.PMID: 11238900 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities.

    Tremblay F, Lavigne C, Jacques H, Marette A.

    Diabetes. 2001 Aug;50(8):1901-10.PMID: 11473054 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.

    Beeson M, Sajan MP, Dizon M, Grebenev D, Gomez-Daspet J, Miura A, Kanoh Y, Powe J, Bandyopadhyay G, Standaert ML, Farese RV.

    Diabetes. 2003 Aug;52(8):1926-34.PMID: 12882907 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats.

    Kanoh Y, Bandyopadhyay G, Sajan MP, Standaert ML, Farese RV.

    Endocrinology. 2001 Apr;142(4):1595-605.PMID: 11250941 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.

    Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV.

    J Biol Chem. 2004 Jun 11;279(24):24929-34. Epub 2004 Apr 6.PMID: 15069067 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle.

    Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM.

    Diabetes. 2005 Aug;54(8):2351-9.PMID: 16046301 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.

    Herr HJ, Bernard JR, Reeder DW, Rivas DA, Limon JJ, Yaspelkis BB 3rd.

    J Physiol. 2005 Jun 1;565(Pt 2):627-36. Epub 2005 Mar 31.PMID: 15802290 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota.

    Standaert ML, Ortmeyer HK, Sajan MP, Kanoh Y, Bandyopadhyay G, Hansen BC, Farese RV.

    Diabetes. 2002 Oct;51(10):2936-43.PMID: 12351430 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.

    Sasaoka T, Hori H, Wada T, Ishiki M, Haruta T, Ishihara H, Kobayashi M.

    Diabetologia. 2001 Oct;44(10):1258-67.PMID: 11692174 [PubMed - indexed for MEDLINE]Related articles

    12.

    Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity.

    Sasaoka T, Wada T, Tsuneki H.

    Pharmacol Ther. 2006 Dec;112(3):799-809. Epub 2006 Jul 13. Review.PMID: 16842857 [PubMed - indexed for MEDLINE]Related articles

    13.

    Dietary cod protein restores insulin-induced activation of phosphatidylinositol 3-kinase/Akt and GLUT4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats.

    Tremblay F, Lavigne C, Jacques H, Marette A.

    Diabetes. 2003 Jan;52(1):29-37.PMID: 12502490 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1.

    Chen HC, Rao M, Sajan MP, Standaert M, Kanoh Y, Miura A, Farese RV Jr, Farese RV.

    Diabetes. 2004 Jun;53(6):1445-51.PMID: 15161747 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.

    Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA.

    J Clin Endocrinol Metab. 2004 Mar;89(3):1301-11.PMID: 15001626 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].

    Storgaard H, Song XM, Jensen CB, Madsbad S, Björnholm M, Vaag A, Zierath JR.

    Diabetes. 2001 Dec;50(12):2770-8. Erratum in: Diabetes 2002 Feb;51(2):552. PMID: 11723060 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Defective activation of atypical protein kinase C zeta and lambda by insulin and phosphatidylinositol-3,4,5-(PO4)(3) in skeletal muscle of rats following high-fat feeding and streptozotocin-induced diabetes.

    Kanoh Y, Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Farese RV.

    Endocrinology. 2003 Mar;144(3):947-54.PMID: 12586772 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes.

    Sasaoka T, Wada T, Fukui K, Murakami S, Ishihara H, Suzuki R, Tobe K, Kadowaki T, Kobayashi M.

    J Biol Chem. 2004 Apr 9;279(15):14835-43. Epub 2004 Jan 26.PMID: 14744864 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade.

    Bertelli DF, Ueno M, Amaral ME, Toyama MH, Carneiro EM, Marangoni S, Carvalho CR, Saad MJ, Velloso LA, Boschero AC.

    Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E679-87. Epub 2002 Nov 26.PMID: 12453826 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice.

    Kagawa S, Soeda Y, Ishihara H, Oya T, Sasahara M, Yaguchi S, Oshita R, Wada T, Tsuneki H, Sasaoka T.

    Endocrinology. 2008 Feb;149(2):642-50. Epub 2007 Nov 26.PMID: 18039790 [PubMed - indexed for MEDLINE]Related articlesFree article

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