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Hyperketonemia increases tumor necrosis factor-alpha secretion in cultured U937 monocytes and Type 1 diabetic patients and is apparently mediated by oxidative stress and cAMP deficiency.
Jain SK, Kannan K, Lim G, McVie R, Bocchini JA Jr.
Diabetes. 2002 Jul;51(7):2287-93.PMID: 12086962 [PubMed - indexed for MEDLINE]Related articlesFree article
Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes.
Jain SK, Kannan K, Lim G, Matthews-Greer J, McVie R, Bocchini JA Jr.
Diabetes Care. 2003 Jul;26(7):2139-43.PMID: 12832326 [PubMed - indexed for MEDLINE]Related articlesFree article
Chromium chloride inhibits oxidative stress and TNF-alpha secretion caused by exposure to high glucose in cultured U937 monocytes.
Jain SK, Kannan K.
Biochem Biophys Res Commun. 2001 Dec 7;289(3):687-91.PMID: 11726202 [PubMed - indexed for MEDLINE]Related articles
Hyperketonemia can increase lipid peroxidation and lower glutathione levels in human erythrocytes in vitro and in type 1 diabetic patients.
Jain SK, McVie R.
Diabetes. 1999 Sep;48(9):1850-5.PMID: 10480618 [PubMed - indexed for MEDLINE]Related articlesFree article
Hyperketonemia (acetoacetate) increases the oxidizability of LDL + VLDL in Type-I diabetic patients.
Jain SK, McVie R, Jaramillo JJ, Chen Y.
Free Radic Biol Med. 1998 Jan 1;24(1):175-81.PMID: 9436628 [PubMed - indexed for MEDLINE]Related articles
Effect of hyperketonemia on blood monocytes in type-I diabetic patients and apoptosis in cultured U937 monocytes.
Jain SK, Kannan K, McVie R.
Antioxid Redox Signal. 1999 Summer;1(2):211-20.PMID: 11228748 [PubMed - indexed for MEDLINE]Related articles
Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways.
Guha M, Bai W, Nadler JL, Natarajan R.
J Biol Chem. 2000 Jun 9;275(23):17728-39.PMID: 10837498 [PubMed - indexed for MEDLINE]Related articlesFree article
Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats.
Jain SK, Rains J, Croad J, Larson B, Jones K.
Antioxid Redox Signal. 2009 Feb;11(2):241-9.PMID: 18976114 [PubMed - indexed for MEDLINE]Related articles
High glucose and ketosis (acetoacetate) increases, and chromium niacinate decreases, IL-6, IL-8, and MCP-1 secretion and oxidative stress in U937 monocytes.
Jain SK, Rains JL, Croad JL.
Antioxid Redox Signal. 2007 Oct;9(10):1581-90.PMID: 17665966 [PubMed - indexed for MEDLINE]Related articles
Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A.
Biochem J. 2002 Dec 15;368(Pt 3):705-20.PMID: 12206715 [PubMed - indexed for MEDLINE]Related articlesFree article
Tumor necrosis factor-alpha stimulates fractalkine production by mesangial cells and regulates monocyte transmigration: down-regulation by cAMP.
Chen YM, Lin SL, Chen CW, Chiang WC, Tsai TJ, Hsieh BS.
Kidney Int. 2003 Feb;63(2):474-86.PMID: 12631113 [PubMed - indexed for MEDLINE]Related articles
Acetoacetate activation of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in primary cultured rat hepatocytes: role of oxidative stress.
Abdelmegeed MA, Kim SK, Woodcroft KJ, Novak RF.
J Pharmacol Exp Ther. 2004 Aug;310(2):728-36. Epub 2004 Mar 29.PMID: 15051799 [PubMed - indexed for MEDLINE]Related articlesFree article
Nitric oxide increases tumor necrosis factor production in differentiated U937 cells by decreasing cyclic AMP.
Wang S, Yan L, Wesley RA, Danner RL.
J Biol Chem. 1997 Feb 28;272(9):5959-65.PMID: 9038216 [PubMed - indexed for MEDLINE]Related articlesFree article
Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation.
Fan X, Subramaniam R, Weiss MF, Monnier VM.
Arch Biochem Biophys. 2003 Jan 15;409(2):274-86.PMID: 12504894 [PubMed - indexed for MEDLINE]Related articles
Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes.
Pelletier A, Coderre L.
Am J Physiol Endocrinol Metab. 2007 May;292(5):E1325-32. Epub 2007 Jan 16.PMID: 17227964 [PubMed - indexed for MEDLINE]Related articlesFree article
Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-kappaB-dependent pathways in cultured human umbilical vein endothelial cells.
Hamaguchi E, Takamura T, Shimizu A, Nagai Y.
J Pharmacol Exp Ther. 2003 Dec;307(3):987-94. Epub 2003 Oct 8.PMID: 14534369 [PubMed - indexed for MEDLINE]Related articlesFree article
TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway.
Jamaluddin M, Wang S, Boldogh I, Tian B, Brasier AR.
Cell Signal. 2007 Jul;19(7):1419-33. Epub 2007 Jan 25.PMID: 17317104 [PubMed - indexed for MEDLINE]Related articles
Anti-inflammatory effects of moxifloxacin on activated human monocytic cells: inhibition of NF-kappaB and mitogen-activated protein kinase activation and of synthesis of proinflammatory cytokines.
Weiss T, Shalit I, Blau H, Werber S, Halperin D, Levitov A, Fabian I.
Antimicrob Agents Chemother. 2004 Jun;48(6):1974-82.PMID: 15155187 [PubMed - indexed for MEDLINE]Related articlesFree article
Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis.
Foey AD, Field S, Ahmed S, Jain A, Feldmann M, Brennan FM, Williams R.
Arthritis Res Ther. 2003;5(6):R317-28. Epub 2003 Sep 3.PMID: 14680506 [PubMed - indexed for MEDLINE]Related articlesFree article
Hyperketonemia (ketosis), oxidative stress and type 1 diabetes.
Jain SK, McVie R, Bocchini JA Jr.
Pathophysiology. 2006 Aug;13(3):163-70. Epub 2006 Jun 19.PMID: 16782314 [PubMed - in process]Related articles
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