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    Results: 1 to 20 of 698

    1.

    Negative regulation of rho signaling by insulin and its impact on actin cytoskeleton organization in vascular smooth muscle cells: role of nitric oxide and cyclic guanosine monophosphate signaling pathways.

    Begum N, Sandu OA, Duddy N.

    Diabetes. 2002 Jul;51(7):2256-63.PMID: 12086958 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Selected contribution: insulin utilizes NO/cGMP pathway to activate myosin phosphatase via Rho inhibition in vascular smooth muscle.

    Sandu OA, Ito M, Begum N.

    J Appl Physiol. 2001 Sep;91(3):1475-82.PMID: 11509551 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Regulation of myosin-bound protein phosphatase by insulin in vascular smooth muscle cells: evaluation of the role of Rho kinase and phosphatidylinositol-3-kinase-dependent signaling pathways.

    Begum N, Duddy N, Sandu O, Reinzie J, Ragolia L.

    Mol Endocrinol. 2000 Sep;14(9):1365-76.PMID: 10976915 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Active Rho kinase (ROK-alpha ) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells.

    Begum N, Sandu OA, Ito M, Lohmann SM, Smolenski A.

    J Biol Chem. 2002 Feb 22;277(8):6214-22. Epub 2001 Dec 5.PMID: 11739394 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Diabetes in the Goto-Kakizaki rat is accompanied by impaired insulin-mediated myosin-bound phosphatase activation and vascular smooth muscle cell relaxation.

    Sandu OA, Ragolia L, Begum N.

    Diabetes. 2000 Dec;49(12):2178-89.PMID: 11118023 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle.

    Sauzeau V, Le Jeune H, Cario-Toumaniantz C, Smolenski A, Lohmann SM, Bertoglio J, Chardin P, Pacaud P, Loirand G.

    J Biol Chem. 2000 Jul 14;275(28):21722-9.PMID: 10783386 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.

    Seko T, Ito M, Kureishi Y, Okamoto R, Moriki N, Onishi K, Isaka N, Hartshorne DJ, Nakano T.

    Circ Res. 2003 Mar 7;92(4):411-8. Epub 2003 Feb 6.PMID: 12600888 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells.

    Pang H, Guo Z, Su W, Xie Z, Eto M, Gong MC.

    Am J Physiol Cell Physiol. 2005 Aug;289(2):C352-60. Epub 2005 Apr 6.PMID: 15814590 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Nitric oxide-induced decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho kinase pathway.

    Bolz SS, Vogel L, Sollinger D, Derwand R, de Wit C, Loirand G, Pohl U.

    Circulation. 2003 Jun 24;107(24):3081-7. Epub 2003 Jun 9.PMID: 12796138 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    P2Y(1), P2Y(2), P2Y(4), and P2Y(6) receptors are coupled to Rho and Rho kinase activation in vascular myocytes.

    Sauzeau V, Le Jeune H, Cario-Toumaniantz C, Vaillant N, Gadeau AP, Desgranges C, Scalbert E, Chardin P, Pacaud P, Loirand G.

    Am J Physiol Heart Circ Physiol. 2000 Jun;278(6):H1751-61.PMID: 10843869 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Thrombin-induced phosphorylation of the regulatory light chain of myosin II in cultured bovine corneal endothelial cells.

    Satpathy M, Gallagher P, Lizotte-Waniewski M, Srinivas SP.

    Exp Eye Res. 2004 Oct;79(4):477-86.PMID: 15381032 [PubMed - indexed for MEDLINE]Related articles

    12.

    Insulin signaling in the vasculature.

    Begum N.

    Front Biosci. 2003 Sep 1;8:s796-804. Review.PMID: 12957877 [PubMed - indexed for MEDLINE]Related articles

    13.

    Ste20-related kinase SLK phosphorylates Ser188 of RhoA to induce vasodilation in response to angiotensin II Type 2 receptor activation.

    Guilluy C, Rolli-Derkinderen M, Loufrani L, Bourgé A, Henrion D, Sabourin L, Loirand G, Pacaud P.

    Circ Res. 2008 May 23;102(10):1265-74. Epub 2008 Apr 17.PMID: 18420945 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Nitric oxide induces dilation of rat aorta via inhibition of rho-kinase signaling.

    Chitaley K, Webb RC.

    Hypertension. 2002 Feb;39(2 Pt 2):438-42.PMID: 11882586 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability.

    Clements RT, Minnear FL, Singer HA, Keller RS, Vincent PA.

    Am J Physiol Lung Cell Mol Physiol. 2005 Feb;288(2):L294-306. Epub 2004 Oct 8.PMID: 15475381 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Smooth muscle F-actin disassembly and RhoA/Rho-kinase signaling during endotoxin-induced alterations in pulmonary arterial compliance.

    Boer C, van Nieuw Amerongen GP, Groeneveld AB, Scheffer GJ, de Lange JJ, Westerhof N, van Hinsbergh VW, Sipkema P.

    Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L649-55. Epub 2003 Sep 26.PMID: 14514519 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction.

    Sakurada S, Takuwa N, Sugimoto N, Wang Y, Seto M, Sasaki Y, Takuwa Y.

    Circ Res. 2003 Sep 19;93(6):548-56. Epub 2003 Aug 14.PMID: 12919947 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.

    Gohla A, Schultz G, Offermanns S.

    Circ Res. 2000 Aug 4;87(3):221-7.PMID: 10926873 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA.

    Edlund S, Landström M, Heldin CH, Aspenström P.

    Mol Biol Cell. 2002 Mar;13(3):902-14.PMID: 11907271 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Mechanotransduction of rat aortic vascular smooth muscle cells requires RhoA and intact actin filaments.

    Numaguchi K, Eguchi S, Yamakawa T, Motley ED, Inagami T.

    Circ Res. 1999 Jul 9;85(1):5-11.PMID: 10400905 [PubMed - indexed for MEDLINE]Related articlesFree article

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