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    Results: 1 to 20 of 191

    1.

    Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.

    Freshwater JD, Svensson CI, Malmberg AB, Calcutt NA.

    Diabetes. 2002 Jul;51(7):2249-55.PMID: 12086957 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.

    Yaksh TL, Dirig DM, Conway CM, Svensson C, Luo ZD, Isakson PC.

    J Neurosci. 2001 Aug 15;21(16):5847-53.PMID: 11487607 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord.

    Tegeder I, Niederberger E, Vetter G, Bräutigam L, Geisslinger G.

    J Neurochem. 2001 Nov;79(4):777-86.PMID: 11723170 [PubMed - indexed for MEDLINE]Related articles

    4.

    Intrathecal protease-activated receptor stimulation produces thermal hyperalgesia through spinal cyclooxygenase activity.

    Koetzner L, Gregory JA, Yaksh TL.

    J Pharmacol Exp Ther. 2004 Oct;311(1):356-63. Epub 2004 Jun 2.PMID: 15175421 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats.

    Malmberg AB, Yaksh TL.

    J Neurosci. 1995 Apr;15(4):2768-76.PMID: 7722627 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Nonopioid actions of intrathecal dynorphin evoke spinal excitatory amino acid and prostaglandin E2 release mediated by cyclooxygenase-1 and -2.

    Koetzner L, Hua XY, Lai J, Porreca F, Yaksh T.

    J Neurosci. 2004 Feb 11;24(6):1451-8.PMID: 14960618 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Nonsteroidal anti-inflammatory drugs increase expression of inducible COX-2 isoform of cyclooxygenase in spinal cord of rats with adjuvant induced inflammation.

    Hsueh SF, Lu CY, Chao CS, Tan PH, Huang YW, Hsieh SW, Hsiao HT, Chung NC, Lin SH, Huang PL, Lyu PC, Yang LC.

    Brain Res Mol Brain Res. 2004 Jun 18;125(1-2):113-9.PMID: 15193428 [PubMed - indexed for MEDLINE]Related articles

    8.

    Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats.

    Calcutt NA, Stiller C, Gustafsson H, Malmberg AB.

    Brain Res. 2000 Feb 21;856(1-2):20-7.PMID: 10677607 [PubMed - indexed for MEDLINE]Related articles

    9.

    The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity.

    Lee IO, Seo Y.

    Anesth Analg. 2008 Mar;106(3):972-7, table of contents.PMID: 18292448 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Pathogenesis of spinally mediated hyperalgesia in diabetes.

    Ramos KM, Jiang Y, Svensson CI, Calcutt NA.

    Diabetes. 2007 Jun;56(6):1569-76. Epub 2007 Feb 7.PMID: 17287466 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Inhibition of noxious stimulus-induced spinal prostaglandin E2 release by flurbiprofen enantiomers: a microdialysis study.

    Geisslinger G, Muth-Selbach U, Coste O, Vetter G, Schrödter A, Schaible HG, Brune K, Tegeder I.

    J Neurochem. 2000 May;74(5):2094-100.PMID: 10800954 [PubMed - indexed for MEDLINE]Related articles

    12.

    Synergistic anti-hyperalgesia of electroacupuncture and low dose of celecoxib in monoarthritic rats: involvement of the cyclooxygenase activity in the spinal cord.

    Mi WL, Mao-Ying QL, Liu Q, Wang XW, Wang YQ, Wu GC.

    Brain Res Bull. 2008 Sep 30;77(2-3):98-104. Epub 2008 May 19.PMID: 18721668 [PubMed - indexed for MEDLINE]Related articles

    13.

    The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia.

    Hay CH, Trevethick MA, Wheeldon A, Bowers JS, de Belleroche JS.

    Neuroscience. 1997 Jun;78(3):843-50.PMID: 9153662 [PubMed - indexed for MEDLINE]Related articles

    14.

    Effect of spinal cyclooxygenase inhibitors in rat using the formalin test and in vitro prostaglandin E2 release.

    Dirig DM, Konin GP, Isakson PC, Yaksh TL.

    Eur J Pharmacol. 1997 Jul 23;331(2-3):155-60.PMID: 9274974 [PubMed - indexed for MEDLINE]Related articles

    15.

    Spinal nerve injury activates prostaglandin synthesis in the spinal cord that contributes to early maintenance of tactile allodynia.

    Hefferan MP, Carter P, Haley M, Loomis CW.

    Pain. 2003 Jan;101(1-2):139-47.PMID: 12507708 [PubMed - indexed for MEDLINE]Related articles

    16.

    The role of cyclooxygenase-1 and -2 in the rat formalin test.

    Yamamoto T, Nozaki-Taguchi N.

    Anesth Analg. 2002 Apr;94(4):962-7, table of contents.PMID: 11916805 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.

    Malmberg AB, O'Connor WT, Glennon JC, Ceseña R, Calcutt NA.

    Brain Res. 2006 Oct 18;1115(1):48-53. Epub 2006 Aug 22.PMID: 16920081 [PubMed - indexed for MEDLINE]Related articles

    18.

    Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia.

    Ibuki T, Matsumura K, Yamazaki Y, Nozaki T, Tanaka Y, Kobayashi S.

    J Neurochem. 2003 Jul;86(2):318-28.PMID: 12871573 [PubMed - indexed for MEDLINE]Related articles

    19.

    Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitor.

    Yamamoto T, Nozaki-Taguchi N.

    Brain Res. 1996 Nov 11;739(1-2):104-10.PMID: 8955930 [PubMed - indexed for MEDLINE]Related articles

    20.

    Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats.

    Zhao Z, Chen SR, Eisenach JC, Busija DW, Pan HL.

    Neuroscience. 2000;97(4):743-8.PMID: 10842019 [PubMed - indexed for MEDLINE]Related articles

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