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    Results: 1 to 20 of 593

    1.

    Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome.

    Buhl ES, Jessen N, Pold R, Ledet T, Flyvbjerg A, Pedersen SB, Pedersen O, Schmitz O, Lund S.

    Diabetes. 2002 Jul;51(7):2199-206.PMID: 12086950 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

    Bergeron R, Previs SF, Cline GW, Perret P, Russell RR 3rd, Young LH, Shulman GI.

    Diabetes. 2001 May;50(5):1076-82.PMID: 11334411 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner.

    Buhl ES, Jessen N, Schmitz O, Pedersen SB, Pedersen O, Holman GD, Lund S.

    Diabetes. 2001 Jan;50(1):12-7.PMID: 11147776 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations.

    Halseth AE, Ensor NJ, White TA, Ross SA, Gulve EA.

    Biochem Biophys Res Commun. 2002 Jun 21;294(4):798-805.PMID: 12061777 [PubMed - indexed for MEDLINE]Related articles

    5.

    AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats.

    Iglesias MA, Ye JM, Frangioudakis G, Saha AK, Tomas E, Ruderman NB, Cooney GJ, Kraegen EW.

    Diabetes. 2002 Oct;51(10):2886-94. Erratum in: Diabetes 2003 Jan;52(1):223-4. PMID: 12351423 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles.

    Jessen N, Pold R, Buhl ES, Jensen LS, Schmitz O, Lund S.

    J Appl Physiol. 2003 Apr;94(4):1373-9. Epub 2002 Dec 20.PMID: 12496137 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo.

    Iglesias MA, Furler SM, Cooney GJ, Kraegen EW, Ye JM.

    Diabetes. 2004 Jul;53(7):1649-54.PMID: 15220186 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle.

    Olsen GS, Hansen BF.

    Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E965-70.PMID: 12376323 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle.

    Stoppani J, Hildebrandt AL, Sakamoto K, Cameron-Smith D, Goodyear LJ, Neufer PD.

    Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1239-48. Epub 2002 Sep 11.PMID: 12388122 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Inhibition of insulin-stimulated glycogen synthesis by 5-aminoimidasole-4-carboxamide-1-beta-d-ribofuranoside-induced adenosine 5'-monophosphate-activated protein kinase activation: interactions with Akt, glycogen synthase kinase 3-3alpha/beta, and glycogen synthase in isolated rat soleus muscle.

    Fediuc S, Gaidhu MP, Ceddia RB.

    Endocrinology. 2006 Nov;147(11):5170-7. Epub 2006 Jul 27.PMID: 16873531 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake.

    Al-Khalili L, Krook A, Zierath JR, Cartee GD.

    Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E553-7. Epub 2004 May 18.PMID: 15149951 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    In vivo metformin treatment ameliorates insulin resistance: evidence for potentiation of insulin-induced translocation and increased functional activity of glucose transporters in obese (fa/fa) Zucker rat adipocytes.

    Matthaei S, Reibold JP, Hamann A, Benecke H, Häring HU, Greten H, Klein HH.

    Endocrinology. 1993 Jul;133(1):304-11.PMID: 8391425 [PubMed - indexed for MEDLINE]Related articles

    13.

    5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-induced AMP-activated protein kinase phosphorylation inhibits basal and insulin-stimulated glucose uptake, lipid synthesis, and fatty acid oxidation in isolated rat adipocytes.

    Gaidhu MP, Fediuc S, Ceddia RB.

    J Biol Chem. 2006 Sep 8;281(36):25956-64. Epub 2006 Jul 1.PMID: 16816404 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR.

    Russell RR 3rd, Bergeron R, Shulman GI, Young LH.

    Am J Physiol. 1999 Aug;277(2 Pt 2):H643-9.PMID: 10444490 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.

    Koistinen HA, Galuska D, Chibalin AV, Yang J, Zierath JR, Holman GD, Wallberg-Henriksson H.

    Diabetes. 2003 May;52(5):1066-72.PMID: 12716734 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

    Ségalen C, Longnus SL, Baetz D, Counillon L, Van Obberghen E.

    Endocrinology. 2008 Apr;149(4):1490-8. Epub 2008 Jan 10.PMID: 18187546 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats.

    Cefalu WT, Wang ZQ, Zhang XH, Baldor LC, Russell JC.

    J Nutr. 2002 Jun;132(6):1107-14.PMID: 12042418 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Effect of chronic bradykinin administration on insulin action in an animal model of insulin resistance.

    Henriksen EJ, Jacob S, Fogt DL, Dietze GJ.

    Am J Physiol. 1998 Jul;275(1 Pt 2):R40-5.PMID: 9688958 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition.

    Yu X, McCorkle S, Wang M, Lee Y, Li J, Saha AK, Unger RH, Ruderman NB.

    Diabetologia. 2004 Nov;47(11):2012-21. Epub 2004 Dec 2.PMID: 15578153 [PubMed - indexed for MEDLINE]Related articles

    20.

    Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output.

    Camacho RC, Pencek RR, Lacy DB, James FD, Donahue EP, Wasserman DH.

    Diabetes. 2005 Feb;54(2):373-82.PMID: 15677495 [PubMed - indexed for MEDLINE]Related articlesFree article

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