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    Results: 1 to 20 of 215

    1.

    Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.

    Geisler JG, Zawalich W, Zawalich K, Lakey JR, Stukenbrok H, Milici AJ, Soeller WC.

    Diabetes. 2002 Jul;51(7):2158-69.PMID: 12086946 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

    Soeller WC, Janson J, Hart SE, Parker JC, Carty MD, Stevenson RW, Kreutter DK, Butler PC.

    Diabetes. 1998 May;47(5):743-50.PMID: 9588445 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.

    Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.

    Diabetes. 2000 Dec;49(12):2056-62.PMID: 11118007 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Estrogenic restoration of functional pancreatic islet cytoarchitecture in diabetes (db/db) mutant C57BL/KsJ mice: relationship to estradiol localization, systemic glycemia, and persistent hyperinsulinemia.

    Garris DR, Garris BL.

    Cell Tissue Res. 2005 Feb;319(2):231-42. Epub 2004 Nov 20.PMID: 15654653 [PubMed - indexed for MEDLINE]Related articles

    5.

    Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

    Verchere CB, D'Alessio DA, Palmiter RD, Weir GC, Bonner-Weir S, Baskin DG, Kahn SE.

    Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3492-6.PMID: 8622964 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.

    Butler AE, Janson J, Soeller WC, Butler PC.

    Diabetes. 2003 Sep;52(9):2304-14.PMID: 12941770 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.

    Janson J, Soeller WC, Roche PC, Nelson RT, Torchia AJ, Kreutter DK, Butler PC.

    Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7283-8.PMID: 8692984 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    [Construction of transgenic mouse system expressing human islet amyloid polypeptide (IAPP)/amylin]

    Yagui K, Kanatsuka A, Makino H.

    Nippon Rinsho. 1994 Oct;52(10):2746-50. Review. Japanese. PMID: 7983808 [PubMed - indexed for MEDLINE]Related articles

    9.

    Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin.

    Yagui K, Yamaguchi T, Kanatsuka A, Shimada F, Huang CI, Tokuyama Y, Ohsawa H, Yamamura K, Miyazaki J, Mikata A, et al.

    Eur J Endocrinol. 1995 Apr;132(4):487-96.PMID: 7711888 [PubMed - indexed for MEDLINE]Related articles

    10.

    Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes.

    Kahn SE, Andrikopoulos S, Verchere CB, Wang F, Hull RL, Vidal J.

    Diabetologia. 2000 Oct;43(10):1309-12.PMID: 11079750 [PubMed - indexed for MEDLINE]Related articles

    11.

    Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.

    Matveyenko AV, Gurlo T, Daval M, Butler AE, Butler PC.

    Diabetes. 2009 Apr;58(4):906-16. Epub 2009 Jan 16.PMID: 19151199 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Amyloid formation in response to beta cell stress occurs in vitro, but not in vivo, in islets of transgenic mice expressing human islet amyloid polypeptide.

    Westermark G, Arora MB, Fox N, Carroll R, Chan SJ, Westermark P, Steiner DF.

    Mol Med. 1995 Jul;1(5):542-53.PMID: 8529120 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse.

    D'Alessio DA, Verchere CB, Kahn SE, Hoagland V, Baskin DG, Palmiter RD, Ensinck JW.

    Diabetes. 1994 Dec;43(12):1457-61.PMID: 7958499 [PubMed - indexed for MEDLINE]Related articles

    14.

    Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction.

    Couce M, Kane LA, O'Brien TD, Charlesworth J, Soeller W, McNeish J, Kreutter D, Roche P, Butler PC.

    Diabetes. 1996 Aug;45(8):1094-101.PMID: 8690157 [PubMed - indexed for MEDLINE]Related articles

    15.

    Molecular physiology of the islet amyloid polypeptide (IAPP)/amylin gene in man, rat, and transgenic mice.

    Höppener JW, Oosterwijk C, van Hulst KL, Verbeek JS, Capel PJ, de Koning EJ, Clark A, Jansz HS, Lips CJ.

    J Cell Biochem. 1994;55 Suppl:39-53. Review.PMID: 7929617 [PubMed - indexed for MEDLINE]Related articles

    16.

    Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP.

    Westermark GT, Gebre-Medhin S, Steiner DF, Westermark P.

    Mol Med. 2000 Dec;6(12):998-1007.PMID: 11474116 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide.

    Hull RL, Shen ZP, Watts MR, Kodama K, Carr DB, Utzschneider KM, Zraika S, Wang F, Kahn SE.

    Diabetes. 2005 Jul;54(7):2235-44.PMID: 15983227 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.

    Matveyenko AV, Butler PC.

    ILAR J. 2006;47(3):225-33. Review.PMID: 16804197 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.

    Hull RL, Andrikopoulos S, Verchere CB, Vidal J, Wang F, Cnop M, Prigeon RL, Kahn SE.

    Diabetes. 2003 Feb;52(2):372-9.PMID: 12540610 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.

    Huang CJ, Haataja L, Gurlo T, Butler AE, Wu X, Soeller WC, Butler PC.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1656-62. Epub 2007 Oct 2.PMID: 17911343 [PubMed - indexed for MEDLINE]Related articlesFree article

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