PubMed

Adrenalectomy improves diabetes in A-ZIP/F-1 lipoatrophic mice by increasing both liver and muscle insulin sensitivity.

Haluzik M, Dietz KR, Kim JK, Marcus-Samuels B, Shulman GI, Gavrilova O, Reitman ML.

Diabetes. 2002 Jul;51(7):2113-8.PMID: 12086940 [PubMed - indexed for MEDLINE]Related articlesFree article

WY14,643, a peroxisome proliferator-activated receptor alpha (PPARalpha ) agonist, improves hepatic and muscle steatosis and reverses insulin resistance in lipoatrophic A-ZIP/F-1 mice.

Chou CJ, Haluzik M, Gregory C, Dietz KR, Vinson C, Gavrilova O, Reitman ML.

J Biol Chem. 2002 Jul 5;277(27):24484-9. Epub 2002 May 6.PMID: 11994294 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes.

Ebihara K, Ogawa Y, Masuzaki H, Shintani M, Miyanaga F, Aizawa-Abe M, Hayashi T, Hosoda K, Inoue G, Yoshimasa Y, Gavrilova O, Reitman ML, Nakao K.

Diabetes. 2001 Jun;50(6):1440-8.PMID: 11375346 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones.

Chao L, Marcus-Samuels B, Mason MM, Moitra J, Vinson C, Arioglu E, Gavrilova O, Reitman ML.

J Clin Invest. 2000 Nov;106(10):1221-8.PMID: 11086023 [PubMed - indexed for MEDLINE]Related articlesFree article

Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy.

Colombo C, Cutson JJ, Yamauchi T, Vinson C, Kadowaki T, Gavrilova O, Reitman ML.

Diabetes. 2002 Sep;51(9):2727-33.PMID: 12196465 [PubMed - indexed for MEDLINE]Related articlesFree article

A-ZIP/F-1 mice lacking white fat: a model for understanding lipoatrophic diabetes.

Reitman ML, Gavrilova O.

Int J Obes Relat Metab Disord. 2000 Nov;24 Suppl 4:S11-4. Review.PMID: 11126232 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis.

Kim H, Haluzik M, Asghar Z, Yau D, Joseph JW, Fernandez AM, Reitman ML, Yakar S, Stannard B, Heron-Milhavet L, Wheeler MB, LeRoith D.

Diabetes. 2003 Jul;52(7):1770-8.PMID: 12829645 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice.

Muurling M, Mensink RP, Pijl H, Romijn JA, Havekes LM, Voshol PJ.

Metabolism. 2003 Aug;52(8):1078-83.PMID: 12898477 [PubMed - indexed for MEDLINE]Related articles

Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice.

Kim JK, Fillmore JJ, Gavrilova O, Chao L, Higashimori T, Choi H, Kim HJ, Yu C, Chen Y, Qu X, Haluzik M, Reitman ML, Shulman GI.

Diabetes. 2003 Jun;52(6):1311-8.PMID: 12765938 [PubMed - indexed for MEDLINE]Related articlesFree article

Mechanism of insulin resistance in A-ZIP/F-1 fatless mice.

Kim JK, Gavrilova O, Chen Y, Reitman ML, Shulman GI.

J Biol Chem. 2000 Mar 24;275(12):8456-60.PMID: 10722680 [PubMed - indexed for MEDLINE]Related articlesFree article

Adrenocortical changes and arterial hypertension in lipoatrophic A-ZIP/F-1 mice.

Lamounier-Zepter V, Bornstein SR, Kunes J, Zicha J, Krsek M, Ehrhart-Bornstein M, Ziegler CG, Kiessling A, Funk RH, Haluzik M.

Mol Cell Endocrinol. 2008 Jan 2;280(1-2):39-46. Epub 2007 Oct 18.PMID: 18045774 [PubMed - indexed for MEDLINE]Related articles

Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy.

Yang SJ, IglayReger HB, Kadouh HC, Bodary PF.

Diabetologia. 2009 May;52(5):972-81. Epub 2009 Mar 10.PMID: 19277603 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance.

Kim JK, Fillmore JJ, Chen Y, Yu C, Moore IK, Pypaert M, Lutz EP, Kako Y, Velez-Carrasco W, Goldberg IJ, Breslow JL, Shulman GI.

Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7522-7. Epub 2001 Jun 5.PMID: 11390966 [PubMed - indexed for MEDLINE]Related articlesFree article

Phloridzin improves hyperglycemia but not hepatic insulin resistance in a transgenic mouse model of type 2 diabetes.

Zhao H, Yakar S, Gavrilova O, Sun H, Zhang Y, Kim H, Setser J, Jou W, LeRoith D.

Diabetes. 2004 Nov;53(11):2901-9.PMID: 15504971 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways.

Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.

J Biol Chem. 2006 Mar 31;281(13):8748-55. Epub 2006 Jan 23.PMID: 16431926 [PubMed - indexed for MEDLINE]Related articlesFree article

Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice.

Gavrilova O, Marcus-Samuels B, Graham D, Kim JK, Shulman GI, Castle AL, Vinson C, Eckhaus M, Reitman ML.

J Clin Invest. 2000 Feb;105(3):271-8.PMID: 10675352 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

Hong EG, Jung DY, Ko HJ, Zhang Z, Ma Z, Jun JY, Kim JH, Sumner AD, Vary TC, Gardner TW, Bronson SK, Kim JK.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1687-96. Epub 2007 Oct 2.PMID: 17911348 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic gluconeogenesis and the activity of PDH in individual tissues of GTG-obese mice following adrenalectomy.

Blair SC, Greenaway TM, Bryson JM, Phuyal JL, Wensley VR, Caterson ID, Cooney GJ.

Obes Res. 1996 Jul;4(4):367-75.PMID: 8822761 [PubMed - indexed for MEDLINE]Related articles

Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance.

Hazel M, Cooksey RC, Jones D, Parker G, Neidigh JL, Witherbee B, Gulve EA, McClain DA.

Endocrinology. 2004 May;145(5):2118-28. Epub 2003 Dec 18.PMID: 14684615 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of responses to a beta3-adrenergic agonist in lipoatrophic A-ZIP/F-1 mice.

Gavrilova O, Marcus-Samuels B, Reitman ML.

Diabetes. 2000 Nov;49(11):1910-6.PMID: 11078459 [PubMed - indexed for MEDLINE]Related articlesFree article