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Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons.
Dunn-Meynell AA, Routh VH, Kang L, Gaspers L, Levin BE.
Diabetes. 2002 Jul;51(7):2056-65.PMID: 12086933 [PubMed - indexed for MEDLINE]Related articlesFree article
Localization of glucokinase gene expression in the rat brain.
Lynch RM, Tompkins LS, Brooks HL, Dunn-Meynell AA, Levin BE.
Diabetes. 2000 May;49(5):693-700.PMID: 10905475 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing.
Kang L, Dunn-Meynell AA, Routh VH, Gaspers LD, Nagata Y, Nishimura T, Eiki J, Zhang BB, Levin BE.
Diabetes. 2006 Feb;55(2):412-20. Erratum in: Diabetes. 2006 Mar;55(3):862. PMID: 16443775 [PubMed - indexed for MEDLINE]Related articlesFree article
Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons.
Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE.
Diabetes. 2004 Mar;53(3):549-59.PMID: 14988237 [PubMed - indexed for MEDLINE]Related articlesFree article
Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus.
Song Z, Levin BE, McArdle JJ, Bakhos N, Routh VH.
Diabetes. 2001 Dec;50(12):2673-81.PMID: 11723049 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucosensing neurons do more than just sense glucose.
Levin BE.
Int J Obes Relat Metab Disord. 2001 Dec;25 Suppl 5:S68-72. Review.PMID: 11840219 [PubMed - indexed for MEDLINE]Related articlesFree article
Neuronal glucosensing: what do we know after 50 years?
Levin BE, Routh VH, Kang L, Sanders NM, Dunn-Meynell AA.
Diabetes. 2004 Oct;53(10):2521-8. Review.PMID: 15448079 [PubMed - indexed for MEDLINE]Related articlesFree article
Caudal hindbrain lactate infusion alters glucokinase, SUR1, and neuronal substrate fuel transporter gene expression in the dorsal vagal complex, lateral hypothalamic area, and ventromedial nucleus hypothalamus of hypoglycemic male rats.
Vavaiya KV, Briski KP.
Brain Res. 2007 Oct 24;1176:62-70. Epub 2007 Aug 10.PMID: 17889836 [PubMed - indexed for MEDLINE]Related articles
Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.
Kang L, Sanders NM, Dunn-Meynell AA, Gaspers LD, Routh VH, Thomas AP, Levin BE.
Am J Physiol Regul Integr Comp Physiol. 2008 Mar;294(3):R784-92. Epub 2007 Dec 19.PMID: 18094065 [PubMed - indexed for MEDLINE]Related articles
Metabolic sensors: viewing glucosensing neurons from a broader perspective.
Physiol Behav. 2002 Jul;76(3):397-401. Review.PMID: 12117576 [PubMed - indexed for MEDLINE]Related articles
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides.
Wang R, Liu X, Hentges ST, Dunn-Meynell AA, Levin BE, Wang W, Routh VH.
Diabetes. 2004 Aug;53(8):1959-65.PMID: 15277373 [PubMed - indexed for MEDLINE]Related articlesFree article
Ventromedial hypothalamic glucokinase is an important mediator of the counterregulatory response to insulin-induced hypoglycemia.
Levin BE, Becker TC, Eiki J, Zhang BB, Dunn-Meynell AA.
Diabetes. 2008 May;57(5):1371-9. Epub 2008 Feb 21.PMID: 18292346 [PubMed - indexed for MEDLINE]Related articlesFree article
Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem.
Balfour RH, Hansen AM, Trapp S.
J Physiol. 2006 Feb 1;570(Pt 3):469-84. Epub 2005 Nov 10.PMID: 16284073 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus.
Song Z, Routh VH.
Diabetes. 2005 Jan;54(1):15-22.PMID: 15616006 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of glucose and insulin on glucokinase activity in rat hypothalamus.
Sanz C, Roncero I, Vázquez P, Navas MA, Blázquez E.
J Endocrinol. 2007 May;193(2):259-67.PMID: 17470517 [PubMed - indexed for MEDLINE]Related articlesFree article
Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut.
Jetton TL, Liang Y, Pettepher CC, Zimmerman EC, Cox FG, Horvath K, Matschinsky FM, Magnuson MA.
J Biol Chem. 1994 Feb 4;269(5):3641-54.PMID: 8106409 [PubMed - indexed for MEDLINE]Related articlesFree article
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks?
Fioramonti X, Contié S, Song Z, Routh VH, Lorsignol A, Pénicaud L.
Diabetes. 2007 May;56(5):1219-27. Epub 2007 Jan 29.PMID: 17261674 [PubMed - indexed for MEDLINE]Related articlesFree article
Third ventricular alloxan reversibly impairs glucose counterregulatory responses.
Sanders NM, Dunn-Meynell AA, Levin BE.
Diabetes. 2004 May;53(5):1230-6.PMID: 15111491 [PubMed - indexed for MEDLINE]Related articlesFree article
In vitro increase in intracellular calcium concentrations induced by low or high extracellular glucose levels in ependymocytes and serotonergic neurons of the rat lower brainstem.
Moriyama R, Tsukamura H, Kinoshita M, Okazaki H, Kato Y, Maeda K.
Endocrinology. 2004 May;145(5):2507-15. Epub 2004 Feb 12.PMID: 14962992 [PubMed - indexed for MEDLINE]Related articlesFree article
Short-term food restriction and refeeding alter expression of genes likely involved in brain glucosensing.
Zhou J, Roane DS, Xi X, Bogacka I, Li B, Ryan DH, Martin RJ.
Exp Biol Med (Maywood). 2003 Sep;228(8):943-50.PMID: 12968066 [PubMed - indexed for MEDLINE]Related articlesFree article
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