My NCBI | Sign In
RSS Settings
  • Search:

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

    Results: 1 to 20 of 137

    1.

    Targeted disruption of the protein tyrosine phosphatase-like molecule IA-2 results in alterations in glucose tolerance tests and insulin secretion.

    Saeki K, Zhu M, Kubosaki A, Xie J, Lan MS, Notkins AL.

    Diabetes. 2002 Jun;51(6):1842-50.PMID: 12031972 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice.

    Kubosaki A, Gross S, Miura J, Saeki K, Zhu M, Nakamura S, Hendriks W, Notkins AL.

    Diabetes. 2004 Jul;53(7):1684-91.PMID: 15220191 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion.

    Harashima S, Clark A, Christie MR, Notkins AL.

    Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8704-9. Epub 2005 Jun 6.PMID: 15939893 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Dense core vesicle proteins IA-2 and IA-2beta: metabolic alterations in double knockout mice.

    Kubosaki A, Nakamura S, Notkins AL.

    Diabetes. 2005 Dec;54 Suppl 2:S46-51.PMID: 16306340 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.

    Doi A, Shono T, Nishi M, Furuta H, Sasaki H, Nanjo K.

    Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):885-90. Epub 2006 Jan 17.PMID: 16418280 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life.

    Löbner K, Steinbrenner H, Roberts GA, Ling Z, Huang GC, Piquer S, Pipeleers DG, Seissler J, Christie MR.

    Diabetes. 2002 Oct;51(10):2982-8.PMID: 12351437 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Disruption of the transmembrane dense core vesicle proteins IA-2 and IA-2beta causes female infertility.

    Kubosaki A, Nakamura S, Clark A, Morris JF, Notkins AL.

    Endocrinology. 2006 Feb;147(2):811-5. Epub 2005 Nov 3.PMID: 16269463 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.

    Seissler J, Nguyen TB, Aust G, Steinbrenner H, Scherbaum WA.

    Diabetes. 2000 Jul;49(7):1137-41.PMID: 10909970 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Detection of proteolytic cleavages of diabetes-associated protein IA-2 beta in the pancreas and the brain using novel anti-IA-2 beta monoclonal antibodies.

    Kawakami T, Saeki K, Takeyama N, Wu G, Sakudo A, Matsumoto Y, Hayashi T, Onodera T.

    Int J Mol Med. 2007 Aug;20(2):177-85.PMID: 17611635 [PubMed - indexed for MEDLINE]Related articles

    10.

    Glutamic acid decarboxylase and ICA512/IA-2 autoantibodies as disease markers and relationship to residual beta-cell function and glycemic control in young type 1 diabetic patients.

    Zanone MM, Catalfamo E, Pietropaolo SL, Rabbone I, Sacchetti C, Cerutti F, Trucco M, Cavallo-Perin P.

    Metabolism. 2003 Jan;52(1):25-9.PMID: 12524658 [PubMed - indexed for MEDLINE]Related articles

    11.

    Human monoclonal antibodies isolated from type I diabetes patients define multiple epitopes in the protein tyrosine phosphatase-like IA-2 antigen.

    Kolm-Litty V, Berlo S, Bonifacio E, Bearzatto M, Engel AM, Christie M, Ziegler AG, Wild T, Endl J.

    J Immunol. 2000 Oct 15;165(8):4676-84.PMID: 11035111 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Expression of the protein tyrosine phosphatase-like protein IA-2 during pancreatic islet development.

    Roberts C, Roberts GA, Löbner K, Bearzatto M, Clark A, Bonifacio E, Christie MR.

    J Histochem Cytochem. 2001 Jun;49(6):767-76.PMID: 11373323 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The IA-2 interactome.

    Hu YF, Zhang HL, Cai T, Harashima S, Notkins AL.

    Diabetologia. 2005 Dec;48(12):2576-81. Epub 2005 Nov 5.PMID: 16273344 [PubMed - indexed for MEDLINE]Related articles

    14.

    Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.

    Diez J, Park Y, Zeller M, Brown D, Garza D, Ricordi C, Hutton J, Eisenbarth GS, Pugliese A.

    Diabetes. 2001 Apr;50(4):895-900.PMID: 11289059 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    IDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm.

    Zahn TR, Macmorris MA, Dong W, Day R, Hutton JC.

    J Comp Neurol. 2001 Jan 1;429(1):127-43.PMID: 11086294 [PubMed - indexed for MEDLINE]Related articles

    16.

    Humoral autoreactivity to an alternatively spliced variant of ICA512/IA-2 in Type I diabetes.

    Park YS, Kawasaki E, Kelemen K, Yu L, Schiller MR, Rewers M, Mizuta M, Eisenbarth GS, Hutton JC.

    Diabetologia. 2000 Oct;43(10):1293-301.PMID: 11079748 [PubMed - indexed for MEDLINE]Related articles

    17.

    Expression of protein tyrosine phosphatase-like molecule ICA512/IA-2 induces growth arrest in yeast cells and transfected mammalian cell lines.

    Papakonstantinou T, Myers MA, Jois J, Roucou X, Prescott M, Rowley MJ, Mackay IR.

    J Autoimmun. 2001 Aug;17(1):51-61.PMID: 11488637 [PubMed - indexed for MEDLINE]Related articles

    18.

    Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans.

    Cai T, Fukushige T, Notkins AL, Krause M.

    J Neurosci. 2004 Mar 24;24(12):3115-24.PMID: 15044551 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Genomic structure and promoter sequence of the insulin-dependent diabetes mellitus autoantigen, IA-2 (PTPRN).

    Xie J, Zhang B, Lan MS, Notkins AL.

    Genomics. 1998 Dec 1;54(2):338-43.PMID: 9828138 [PubMed - indexed for MEDLINE]Related articles

    20.

    Two distinctly HLA-associated contiguous linear epitopes uniquely expressed within the islet antigen 2 molecule are major autoantibody epitopes of the diabetes-specific tyrosine phosphatase-like protein autoantigens.

    Bearzatto M, Naserke H, Piquer S, Koczwara K, Lampasona V, Williams A, Christie MR, Bingley PJ, Ziegler AG, Bonifacio E.

    J Immunol. 2002 Apr 15;168(8):4202-8.PMID: 11937581 [PubMed - indexed for MEDLINE]Related articlesFree article

    Supplemental Content

    Filter your results:

    Find related data

    Recent activity