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    Results: 1 to 20 of 438

    1.

    The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats.

    Dobbins RL, Szczepaniak LS, Myhill J, Tamura Y, Uchino H, Giacca A, McGarry JD.

    Diabetes. 2002 Jun;51(6):1825-33.PMID: 12031970 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats.

    Mason TM, Goh T, Tchipashvili V, Sandhu H, Gupta N, Lewis GF, Giacca A.

    Diabetes. 1999 Mar;48(3):524-30.PMID: 10078552 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Diabetogenic impact of long-chain omega-3 fatty acids on pancreatic beta-cell function and the regulation of endogenous glucose production.

    Holness MJ, Greenwood GK, Smith ND, Sugden MC.

    Endocrinology. 2003 Sep;144(9):3958-68.PMID: 12933670 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation.

    Stein DT, Stevenson BE, Chester MW, Basit M, Daniels MB, Turley SD, McGarry JD.

    J Clin Invest. 1997 Jul 15;100(2):398-403.PMID: 9218517 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Effects of different free fatty acids on insulin resistance in rats.

    Han P, Zhang YY, Lu Y, He B, Zhang W, Xia F.

    Hepatobiliary Pancreat Dis Int. 2008 Feb;7(1):91-6.PMID: 18234646 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Pancreatic insulin secretion in rats fed a soy protein high fat diet depends on the interaction between the amino acid pattern and isoflavones.

    Noriega-López L, Tovar AR, Gonzalez-Granillo M, Hernández-Pando R, Escalante B, Santillán-Doherty P, Torres N.

    J Biol Chem. 2007 Jul 13;282(28):20657-66. Epub 2007 May 16.PMID: 17507381 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.

    Ahrén B, Simonsson E, Scheurink AJ, Mulder H, Myrsén U, Sundler F.

    Metabolism. 1997 Jan;46(1):97-106.PMID: 9005977 [PubMed - indexed for MEDLINE]Related articles

    8.

    Acute omega-3 fatty acid enrichment selectively reverses high-saturated fat feeding-induced insulin hypersecretion but does not improve peripheral insulin resistance.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    Diabetes. 2004 Feb;53 Suppl 1:S166-71.PMID: 14749283 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    PPARalpha activation reverses adverse effects induced by high-saturated-fat feeding on pancreatic beta-cell function in late pregnancy.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1087-94. Epub 2006 Dec 12.PMID: 17164438 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.

    Carpentier A, Mittelman SD, Lamarche B, Bergman RN, Giacca A, Lewis GF.

    Am J Physiol. 1999 Jun;276(6 Pt 1):E1055-66.PMID: 10362618 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes.

    Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF.

    Diabetes. 2000 Mar;49(3):399-408.PMID: 10868961 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans.

    Dobbins RL, Chester MW, Daniels MB, McGarry JD, Stein DT.

    Diabetes. 1998 Oct;47(10):1613-8.PMID: 9753300 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    High-fat- and lipid-induced insulin resistance in rats: the comparison of glucose metabolism, plasma resistin and adiponectin levels.

    Li L, Yang G, Li Q, Tang Y, Li K.

    Ann Nutr Metab. 2006;50(6):499-505. Epub 2006 Dec 21.PMID: 17191023 [PubMed - indexed for MEDLINE]Related articles

    14.

    PPARalpha activation and increased dietary lipid oppose thyroid hormone signaling and rescue impaired glucose-stimulated insulin secretion in hyperthyroidism.

    Holness MJ, Greenwood GK, Smith ND, Sugden MC.

    Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1380-9. Epub 2008 Oct 14.PMID: 18854422 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Chronic physiologic hyperinsulinemia impairs suppression of plasma free fatty acids and increases de novo lipogenesis but does not cause dyslipidemia in conscious normal rats.

    Koopmans SJ, Kushwaha RS, DeFronzo RA.

    Metabolism. 1999 Mar;48(3):330-7.PMID: 10094109 [PubMed - indexed for MEDLINE]Related articles

    16.

    Dietary fat-induced increase in blood pressure and insulin resistance in rats.

    Yoshioka S, Uemura K, Tamaya N, Tamagawa T, Miura H, Iguchi A, Nakamura J, Hotta N.

    J Hypertens. 2000 Dec;18(12):1857-64.PMID: 11132611 [PubMed - indexed for MEDLINE]Related articles

    17.

    Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men.

    Leung N, Sakaue T, Carpentier A, Uffelman K, Giacca A, Lewis GF.

    Diabetologia. 2004 Feb;47(2):204-13. Epub 2004 Jan 8.PMID: 14712348 [PubMed - indexed for MEDLINE]Related articles

    18.

    A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.

    Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

    Diabetes. 2003 Oct;52(10):2461-74.PMID: 14514628 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Hormone-sensitive lipase has a role in lipid signaling for insulin secretion but is nonessential for the incretin action of glucagon-like peptide 1.

    Peyot ML, Nolan CJ, Soni K, Joly E, Lussier R, Corkey BE, Wang SP, Mitchell GA, Prentki M.

    Diabetes. 2004 Jul;53(7):1733-42.PMID: 15220197 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats.

    Dobbins RL, Szczepaniak LS, Bentley B, Esser V, Myhill J, McGarry JD.

    Diabetes. 2001 Jan;50(1):123-30.PMID: 11147777 [PubMed - indexed for MEDLINE]Related articlesFree article

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