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    Results: 1 to 20 of 124

    1.

    Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation.

    Ozmen L, Ekdahl KN, Elgue G, Larsson R, Korsgren O, Nilsson B.

    Diabetes. 2002 Jun;51(6):1779-84.PMID: 12031965 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes.

    Bennet W, Groth CG, Larsson R, Nilsson B, Korsgren O.

    Ups J Med Sci. 2000;105(2):125-33. Review.PMID: 11095109 [PubMed - indexed for MEDLINE]Related articles

    3.

    Tirofiban and activated protein C synergistically inhibit the Instant Blood Mediated Inflammatory Reaction (IBMIR) from allogeneic islet cells exposure to human blood.

    Akima S, Hawthorne WJ, Favaloro E, Patel A, Blyth K, Mudaliar Y, Chapman JR, O'Connell PJ.

    Am J Transplant. 2009 Jul;9(7):1533-40. Epub 2009 May 20.PMID: 19459790 [PubMed - indexed for MEDLINE]Related articles

    4.

    The role of the innate immunity in islet transplantation.

    Moberg L.

    Ups J Med Sci. 2005;110(1):17-55. Review.PMID: 15801685 [PubMed - indexed for MEDLINE]Related articles

    5.

    Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo.

    Goto M, Johansson H, Maeda A, Elgue G, Korsgren O, Nilsson B.

    Transplant Proc. 2004 May;36(4):1186-7.PMID: 15194411 [PubMed - indexed for MEDLINE]Related articles

    6.

    Neutrophilic granulocytes are the predominant cell type infiltrating pancreatic islets in contact with ABO-compatible blood.

    Moberg L, Korsgren O, Nilsson B.

    Clin Exp Immunol. 2005 Oct;142(1):125-31.PMID: 16178866 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation.

    Johansson H, Goto M, Dufrane D, Siegbahn A, Elgue G, Gianello P, Korsgren O, Nilsson B.

    Am J Transplant. 2006 Feb;6(2):305-12. Erratum in: Am J Transplant. 2006 Jun;6(6):1500. Dufrane, D [added]; Gianello, P [added]. PMID: 16426314 [PubMed - indexed for MEDLINE]Related articles

    8.

    Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation.

    Goto M, Tjernberg J, Dufrane D, Elgue G, Brandhorst D, Ekdahl KN, Brandhorst H, Wennberg L, Kurokawa Y, Satomi S, Lambris JD, Gianello P, Korsgren O, Nilsson B.

    Xenotransplantation. 2008 Jul;15(4):225-34. Erratum in: Xenotransplantation. 2008 Sep;15(5):352. PMID: 18957045 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation.

    Cabric S, Sanchez J, Lundgren T, Foss A, Felldin M, Källen R, Salmela K, Tibell A, Tufveson G, Larsson R, Korsgren O, Nilsson B.

    Diabetes. 2007 Aug;56(8):2008-15. Epub 2007 May 31.PMID: 17540953 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?

    Bennet W, Sundberg B, Groth CG, Brendel MD, Brandhorst D, Brandhorst H, Bretzel RG, Elgue G, Larsson R, Nilsson B, Korsgren O.

    Diabetes. 1999 Oct;48(10):1907-14.PMID: 10512353 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The effect of composite pig islet-human endothelial cell grafts on the instant blood-mediated inflammatory reaction.

    Kim HI, Yu JE, Lee SY, Sul AY, Jang MS, Rashid MA, Park SG, Kim SJ, Park CG, Kim JH, Park KS.

    Cell Transplant. 2009;18(1):31-7.PMID: 19476207 [PubMed - indexed for MEDLINE]Related articles

    12.

    Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin.

    Bennet W, Sundberg B, Lundgren T, Tibell A, Groth CG, Richards A, White DJ, Elgue G, Larsson R, Nilsson B, Korsgren O.

    Transplantation. 2000 Mar 15;69(5):711-9.PMID: 10755515 [PubMed - indexed for MEDLINE]Related articles

    13.

    Composite islet-endothelial cell grafts: a novel approach to counteract innate immunity in islet transplantation.

    Johansson U, Elgue G, Nilsson B, Korsgren O.

    Am J Transplant. 2005 Nov;5(11):2632-9.PMID: 16212622 [PubMed - indexed for MEDLINE]Related articles

    14.

    Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets.

    Goto M, Johansson H, Maeda A, Elgue G, Korsgren O, Nilsson B.

    Transplantation. 2004 Mar 15;77(5):741-7.PMID: 15021838 [PubMed - indexed for MEDLINE]Related articles

    15.

    Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation.

    Moberg L, Johansson H, Lukinius A, Berne C, Foss A, Källen R, Østraat Ø, Salmela K, Tibell A, Tufveson G, Elgue G, Nilsson Ekdahl K, Korsgren O, Nilsson B.

    Lancet. 2002 Dec 21-28;360(9350):2039-45.PMID: 12504401 [PubMed - indexed for MEDLINE]Related articles

    16.

    Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers.

    Wolzt M, Levi M, Sarich TC, Boström SL, Eriksson UG, Eriksson-Lepkowska M, Svensson M, Weitz JI, Elg M, Wåhlander K.

    Thromb Haemost. 2004 Jun;91(6):1090-6.PMID: 15175794 [PubMed - indexed for MEDLINE]Related articles

    17.

    Mechanism of action of the oral direct thrombin inhibitor ximelagatran.

    Mattsson C, Sarich TC, Carlsson SC.

    Semin Vasc Med. 2005 Aug;5(3):235-44. Review.PMID: 16123910 [PubMed - indexed for MEDLINE]Related articles

    18.

    Effects of melagatran, a new low-molecular-weight thrombin inhibitor, on thrombin and fibrinolytic enzymes.

    Gustafsson D, Antonsson T, Bylund R, Eriksson U, Gyzander E, Nilsson I, Elg M, Mattsson C, Deinum J, Pehrsson S, Karlsson O, Nilsson A, Sörensen H.

    Thromb Haemost. 1998 Jan;79(1):110-8.PMID: 9459334 [PubMed - indexed for MEDLINE]Related articles

    19.

    Effect of low and high dose melagatran and other antithrombotic drugs on platelet aggregation.

    Soslau G, Ando A, Floyd L, Hong T, Mathew L, Yen Y.

    J Thromb Thrombolysis. 2008 Apr;25(2):198-203. Epub 2007 Aug 21.PMID: 17710375 [PubMed - indexed for MEDLINE]Related articles

    20.

    Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation.

    Johansson H, Lukinius A, Moberg L, Lundgren T, Berne C, Foss A, Felldin M, Källen R, Salmela K, Tibell A, Tufveson G, Ekdahl KN, Elgue G, Korsgren O, Nilsson B.

    Diabetes. 2005 Jun;54(6):1755-62.PMID: 15919797 [PubMed - indexed for MEDLINE]Related articlesFree article

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