My NCBI | Sign In
RSS Settings
  • Search:

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

    Results: 1 to 20 of 564

    1.

    Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes.

    Matsumoto M, Ogawa W, Teshigawara K, Inoue H, Miyake K, Sakaue H, Kasuga M.

    Diabetes. 2002 Jun;51(6):1672-80.PMID: 12031952 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Role of IRS-3 in the insulin signaling of IRS-1-deficient brown adipocytes.

    Arribas M, Valverde AM, Benito M.

    J Biol Chem. 2003 Nov 14;278(46):45189-99. Epub 2003 Aug 27.PMID: 12944402 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation.

    Mur C, Arribas M, Benito M, Valverde AM.

    Endocrinology. 2003 Feb;144(2):581-93.PMID: 12538620 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes.

    Ribaux PG, Iynedjian PB.

    Biochem J. 2003 Dec 15;376(Pt 3):697-705.PMID: 14505487 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.

    Fasshauer M, Klein J, Kriauciunas KM, Ueki K, Benito M, Kahn CR.

    Mol Cell Biol. 2001 Jan;21(1):319-29.PMID: 11113206 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.

    Laviola L, Belsanti G, Davalli AM, Napoli R, Perrini S, Weir GC, Giorgino R, Giorgino F.

    Diabetes. 2001 Dec;50(12):2709-20.PMID: 11723053 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes.

    Valverde AM, Arribas M, Mur C, Navarro P, Pons S, Cassard-Doulcier AM, Kahn CR, Benito M.

    J Biol Chem. 2003 Mar 21;278(12):10221-31. Epub 2003 Jan 13.PMID: 12525499 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes.

    Valverde AM, Fabregat I, Burks DJ, White MF, Benito M.

    Hepatology. 2004 Dec;40(6):1285-94.PMID: 15565601 [PubMed - indexed for MEDLINE]Related articles

    9.

    A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.

    Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4640-5. Epub 2001 Apr 3.PMID: 11287630 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.

    Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G.

    Endocrinology. 2004 Jun;145(6):2845-57. Epub 2004 Mar 4.PMID: 15001544 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.

    Uddin S, Majchrzak B, Wang PC, Modi S, Khan MK, Fish EN, Platanias LC.

    Biochem Biophys Res Commun. 2000 Apr 2;270(1):158-62.PMID: 10733921 [PubMed - indexed for MEDLINE]Related articles

    12.

    Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes.

    Valverde AM, Burks DJ, Fabregat I, Fisher TL, Carretero J, White MF, Benito M.

    Diabetes. 2003 Sep;52(9):2239-48.PMID: 12941762 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway.

    Hirashima Y, Tsuruzoe K, Kodama S, Igata M, Toyonaga T, Ueki K, Kahn CR, Araki E.

    J Endocrinol. 2003 Nov;179(2):253-66.PMID: 14596677 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.

    Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB.

    Diabetes. 1999 Feb;48(2):310-20.PMID: 10334307 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor.

    Wick KR, Werner ED, Langlais P, Ramos FJ, Dong LQ, Shoelson SE, Liu F.

    J Biol Chem. 2003 Mar 7;278(10):8460-7. Epub 2002 Dec 18.PMID: 12493740 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.

    Hennige AM, Lammers R, Arlt D, Höppner W, Strack V, Niederfellner G, Seif FJ, Häring HU, Kellerer M.

    Mol Cell Endocrinol. 2000 Sep 25;167(1-2):69-76.PMID: 11000521 [PubMed - indexed for MEDLINE]Related articles

    17.

    Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation.

    Harada S, Smith RM, Smith JA, White MF, Jarett L.

    J Biol Chem. 1996 Nov 22;271(47):30222-6. Erratum in: J Biol Chem 1997 Jan 31;272(5):3124. PMID: 8939974 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.

    Yellaturu CR, Deng X, Cagen LM, Wilcox HG, Mansbach CM 2nd, Siddiqi SA, Park EA, Raghow R, Elam MB.

    J Biol Chem. 2009 Mar 20;284(12):7518-32. Epub 2009 Jan 21.PMID: 19158095 [PubMed - indexed for MEDLINE]Related articles

    19.

    Regulation of IRS-1/SHP2 interaction and AKT phosphorylation in animal models of insulin resistance.

    Lima MH, Ueno M, Thirone AC, Rocha EM, Carvalho CR, Saad MJ.

    Endocrine. 2002 Jun;18(1):1-12.PMID: 12166618 [PubMed - indexed for MEDLINE]Related articles

    20.

    GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

    Annerén C, Welsh M.

    Mol Med. 2002 Nov;8(11):705-13.PMID: 12520087 [PubMed - indexed for MEDLINE]Related articlesFree article

    Supplemental Content

    Filter your results:

    Find related data

    Recent activity