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    Results: 1 to 20 of 363

    1.

    MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats.

    Atkinson LL, Kelly SE, Russell JC, Bar-Tana J, Lopaschuk GD.

    Diabetes. 2002 May;51(5):1548-55.PMID: 11978655 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Potential mechanisms and consequences of cardiac triacylglycerol accumulation in insulin-resistant rats.

    Atkinson LL, Kozak R, Kelly SE, Onay Besikci A, Russell JC, Lopaschuk GD.

    Am J Physiol Endocrinol Metab. 2003 May;284(5):E923-30. Epub 2002 Dec 3.PMID: 12464581 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise.

    Park H, Kaushik VK, Constant S, Prentki M, Przybytkowski E, Ruderman NB, Saha AK.

    J Biol Chem. 2002 Sep 6;277(36):32571-7. Epub 2002 Jun 13.PMID: 12065578 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation.

    Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc C, Itani SI, Lodish HF, Ruderman NB.

    Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16309-13. Epub 2002 Nov 27.PMID: 12456889 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Effect of phosphorylation by AMP-activated protein kinase on palmitoyl-CoA inhibition of skeletal muscle acetyl-CoA carboxylase.

    Rubink DS, Winder WW.

    J Appl Physiol. 2005 Apr;98(4):1221-7. Epub 2004 Dec 3.PMID: 15579580 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Skeletal muscle AMP-activated protein kinase phosphorylation parallels metabolic phenotype in leptin transgenic mice under dietary modification.

    Tanaka T, Hidaka S, Masuzaki H, Yasue S, Minokoshi Y, Ebihara K, Chusho H, Ogawa Y, Toyoda T, Sato K, Miyanaga F, Fujimoto M, Tomita T, Kusakabe T, Kobayashi N, Tanioka H, Hayashi T, Hosoda K, Yoshimatsu H, Sakata T, Nakao K.

    Diabetes. 2005 Aug;54(8):2365-74.PMID: 16046303 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells.

    Zang M, Zuccollo A, Hou X, Nagata D, Walsh K, Herscovitz H, Brecher P, Ruderman NB, Cohen RA.

    J Biol Chem. 2004 Nov 12;279(46):47898-905. Epub 2004 Sep 14.PMID: 15371448 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats.

    Kraegen EW, Saha AK, Preston E, Wilks D, Hoy AJ, Cooney GJ, Ruderman NB.

    Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E471-9. Epub 2005 Oct 18.PMID: 16234268 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia.

    Kudo N, Gillespie JG, Kung L, Witters LA, Schulz R, Clanachan AS, Lopaschuk GD.

    Biochim Biophys Acta. 1996 May 31;1301(1-2):67-75.PMID: 8652652 [PubMed - indexed for MEDLINE]Related articles

    10.

    Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16.

    Russell JC, Shillabeer G, Bar-Tana J, Lau DC, Richardson M, Wenzel LM, Graham SE, Dolphin PJ.

    Diabetes. 1998 May;47(5):770-8.PMID: 9588449 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects.

    Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM.

    Diabetes. 2006 Aug;55(8):2277-85.PMID: 16873691 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells.

    Fediuc S, Gaidhu MP, Ceddia RB.

    J Lipid Res. 2006 Feb;47(2):412-20. Epub 2005 Nov 22.PMID: 16304351 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training.

    Sriwijitkamol A, Ivy JL, Christ-Roberts C, DeFronzo RA, Mandarino LJ, Musi N.

    Am J Physiol Endocrinol Metab. 2006 May;290(5):E925-32. Epub 2005 Dec 13.PMID: 16352671 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Upregulation of 5'-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit.

    Makinde AO, Gamble J, Lopaschuk GD.

    Circ Res. 1997 Apr;80(4):482-9.PMID: 9118478 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo.

    Saha AK, Avilucea PR, Ye JM, Assifi MM, Kraegen EW, Ruderman NB.

    Biochem Biophys Res Commun. 2004 Feb 6;314(2):580-5.PMID: 14733947 [PubMed - indexed for MEDLINE]Related articles

    16.

    Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle.

    Vavvas D, Apazidis A, Saha AK, Gamble J, Patel A, Kemp BE, Witters LA, Ruderman NB.

    J Biol Chem. 1997 May 16;272(20):13255-61.PMID: 9148944 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment.

    Steinberg GR, Rush JW, Dyck DJ.

    Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E648-54. Epub 2002 Nov 19.PMID: 12441311 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle.

    Park SH, Gammon SR, Knippers JD, Paulsen SR, Rubink DS, Winder WW.

    J Appl Physiol. 2002 Jun;92(6):2475-82.PMID: 12015362 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin inhibition of 5' adenosine monophosphate-activated protein kinase in the heart results in activation of acetyl coenzyme A carboxylase and inhibition of fatty acid oxidation.

    Gamble J, Lopaschuk GD.

    Metabolism. 1997 Nov;46(11):1270-4.PMID: 9361684 [PubMed - indexed for MEDLINE]Related articles

    20.

    AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats.

    Assifi MM, Suchankova G, Constant S, Prentki M, Saha AK, Ruderman NB.

    Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E794-800. Epub 2005 Jun 14.PMID: 15956049 [PubMed - indexed for MEDLINE]Related articlesFree article

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