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    Results: 1 to 20 of 162

    1.

    Unexpected sensitivity of nonobese diabetic mice with a disrupted poly(ADP-Ribose) polymerase-1 gene to streptozotocin-induced and spontaneous diabetes.

    Gonzalez C, Ménissier De Murcia J, Janiak P, Bidouard JP, Beauvais C, Karray S, Garchon HJ, Lévi-Strauss M.

    Diabetes. 2002 May;51(5):1470-6.PMID: 11978644 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes.

    Pieper AA, Brat DJ, Krug DK, Watkins CC, Gupta A, Blackshaw S, Verma A, Wang ZQ, Snyder SH.

    Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3059-64.PMID: 10077636 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes.

    Suarez-Pinzon WL, Mabley JG, Power R, Szabó C, Rabinovitch A.

    Diabetes. 2003 Jul;52(7):1683-8.PMID: 12829633 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes.

    Masutani M, Suzuki H, Kamada N, Watanabe M, Ueda O, Nozaki T, Jishage K, Watanabe T, Sugimoto T, Nakagama H, Ochiya T, Sugimura T.

    Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2301-4.PMID: 10051636 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.

    Mabley JG, Suarez-Pinzon WL, Haskó G, Salzman AL, Rabinovitch A, Kun E, Szabó C.

    Br J Pharmacol. 2001 Jul;133(6):909-19.PMID: 11454665 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Poly(ADP-ribose)polymerase activation determines strain sensitivity to streptozotocin-induced beta cell death in inbred mice.

    Cardinal JW, Allan DJ, Cameron DP.

    J Mol Endocrinol. 1999 Feb;22(1):65-70.PMID: 9924181 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    A dinucleotide repeat polymorphism at the poly(ADP-ribose) polymerase gene is not associated with predisposition to type 1 diabetes in French Caucasians.

    Delrieu O, Dubois-Laforgue D, Timsit J, Tournier-Lasserve E, Caillat-Zucman S.

    J Autoimmun. 2001 Sep;17(2):137-40.PMID: 11591122 [PubMed - indexed for MEDLINE]Related articles

    8.

    Unusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: role for beta cell-expressed resistance determinants.

    Mathews CE, Graser RT, Savinov A, Serreze DV, Leiter EH.

    Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):235-40.PMID: 11136257 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

    Heller B, Wang ZQ, Wagner EF, Radons J, Bürkle A, Fehsel K, Burkart V, Kolb H.

    J Biol Chem. 1995 May 12;270(19):11176-80.PMID: 7744749 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Increased susceptibility to streptozotocin-induced beta-cell apoptosis and delayed autoimmune diabetes in alkylpurine-DNA-N-glycosylase-deficient mice.

    Cardinal JW, Margison GP, Mynett KJ, Yates AP, Cameron DP, Elder RH.

    Mol Cell Biol. 2001 Aug;21(16):5605-13.PMID: 11463841 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

    Burkart V, Wang ZQ, Radons J, Heller B, Herceg Z, Stingl L, Wagner EF, Kolb H.

    Nat Med. 1999 Mar;5(3):314-9.PMID: 10086388 [PubMed - indexed for MEDLINE]Related articles

    12.

    DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors.

    Okamoto H, Yamamoto H.

    Princess Takamatsu Symp. 1983;13:297-308.PMID: 6317640 [PubMed - indexed for MEDLINE]Related articles

    13.

    The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes.

    Pacher P, Liaudet L, Soriano FG, Mabley JG, Szabó E, Szabó C.

    Diabetes. 2002 Feb;51(2):514-21.PMID: 11812763 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Necrosis is the predominant type of islet cell death during development of insulin-dependent diabetes mellitus in BB rats.

    Fehsel K, Kolb-Bachofen V, Kröncke KD.

    Lab Invest. 2003 Apr;83(4):549-59.PMID: 12695558 [PubMed - indexed for MEDLINE]Related articles

    15.

    Genetic control of non obese diabetic mice susceptibility to high-dose streptozotocin-induced diabetes.

    Gonzalez C, Cuvellier S, Hue-Beauvais C, Lévi-Strauss M.

    Diabetologia. 2003 Sep;46(9):1291-5. Epub 2003 Jul 15.PMID: 12879252 [PubMed - indexed for MEDLINE]Related articles

    16.

    Dysregulated B7-1 and B7-2 expression on nonobese diabetic mouse B cells is associated with increased T cell costimulation and the development of insulitis.

    Hussain S, Delovitch TL.

    J Immunol. 2005 Jan 15;174(2):680-7.PMID: 15634886 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

    Alba A, Puertas MC, Carrillo J, Planas R, Ampudia R, Pastor X, Bosch F, Pujol-Borrell R, Verdaguer J, Vives-Pi M.

    J Immunol. 2004 Dec 1;173(11):6667-75.PMID: 15557158 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Mechanisms of accelerated immune-mediated diabetes resulting from islet beta cell expression of a Fas ligand transgene.

    Silva DG, Petrovsky N, Socha L, Slattery R, Gatenby P, Charlton B.

    J Immunol. 2003 May 15;170(10):4996-5002.PMID: 12734343 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Oxidative stress-induced, poly(ADP-ribose) polymerase-dependent upregulation of ET-1 expression in chronic diabetic complications.

    Chiu J, Xu BY, Chen S, Feng B, Chakrabarti S.

    Can J Physiol Pharmacol. 2008 Jun;86(6):365-72.PMID: 18516100 [PubMed - indexed for MEDLINE]Related articles

    20.

    IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse.

    Balasa B, Van Gunst K, Jung N, Katz JD, Sarvetnick N.

    Cell Immunol. 2000 Jun 15;202(2):97-102.PMID: 10896769 [PubMed - indexed for MEDLINE]Related articles

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