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    Results: 1 to 20 of 728

    1.

    Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the beta-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4.

    Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M, Portha B.

    Diabetes. 2002 May;51(5):1443-52.PMID: 11978641 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age.

    Tourrel C, Bailbé D, Meile MJ, Kergoat M, Portha B.

    Diabetes. 2001 Jul;50(7):1562-70.PMID: 11423477 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

    Movassat J, Saulnier C, Serradas P, Portha B.

    Diabetologia. 1997 Aug;40(8):916-25.PMID: 9267986 [PubMed - indexed for MEDLINE]Related articles

    4.

    Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

    Perfetti R, Zhou J, Doyle ME, Egan JM.

    Endocrinology. 2000 Dec;141(12):4600-5.PMID: 11108273 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

    Xu G, Stoffers DA, Habener JF, Bonner-Weir S.

    Diabetes. 1999 Dec;48(12):2270-6.PMID: 10580413 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations.

    Greig NH, Holloway HW, De Ore KA, Jani D, Wang Y, Zhou J, Garant MJ, Egan JM.

    Diabetologia. 1999 Jan;42(1):45-50.PMID: 10027577 [PubMed - indexed for MEDLINE]Related articles

    7.

    Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro.

    Parkes DG, Pittner R, Jodka C, Smith P, Young A.

    Metabolism. 2001 May;50(5):583-9.PMID: 11319721 [PubMed - indexed for MEDLINE]Related articles

    8.

    Glucagon-like peptide-1.

    Doyle ME, Egan JM.

    Recent Prog Horm Res. 2001;56:377-99. Review.PMID: 11237222 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Impaired beta-cell regeneration after partial pancreatectomy in the adult Goto-Kakizaki rat, a spontaneous model of type II diabetes.

    Plachot C, Movassat J, Portha B.

    Histochem Cell Biol. 2001 Aug;116(2):131-9.PMID: 11685541 [PubMed - indexed for MEDLINE]Related articles

    10.

    Is defective pancreatic beta-cell mass environmentally programmed in Goto-Kakizaki rat model of type 2 diabetes?: insights from crossbreeding studies during suckling period.

    Calderari S, Gangnerau MN, Meile MJ, Portha B, Serradas P.

    Pancreas. 2006 Nov;33(4):412-7.PMID: 17079948 [PubMed - indexed for MEDLINE]Related articles

    11.

    Glucagon-like peptide I enhances the insulinotropic effect of glibenclamide in NIDDM patients and in the perfused rat pancreas.

    Gutniak MK, Juntti-Berggren L, Hellström PM, Guenifi A, Holst JJ, Efendic S.

    Diabetes Care. 1996 Aug;19(8):857-63.PMID: 8842604 [PubMed - indexed for MEDLINE]Related articles

    12.

    Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.

    Wang Q, Brubaker PL.

    Diabetologia. 2002 Sep;45(9):1263-73. Epub 2002 Apr 26.PMID: 12242459 [PubMed - indexed for MEDLINE]Related articles

    13.

    Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus.

    Koyama M, Wada R, Sakuraba H, Mizukami H, Yagihashi S.

    Am J Pathol. 1998 Aug;153(2):537-45.PMID: 9708813 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics.

    Sturis J, Gotfredsen CF, Rømer J, Rolin B, Ribel U, Brand CL, Wilken M, Wassermann K, Deacon CF, Carr RD, Knudsen LB.

    Br J Pharmacol. 2003 Sep;140(1):123-32. Epub 2003 Jul 29.PMID: 12967942 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

    Pospisilik JA, Martin J, Doty T, Ehses JA, Pamir N, Lynn FC, Piteau S, Demuth HU, McIntosh CH, Pederson RA.

    Diabetes. 2003 Mar;52(3):741-50.PMID: 12606516 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.

    Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ.

    J Biol Chem. 2003 Jan 3;278(1):471-8. Epub 2002 Oct 29.PMID: 12409292 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

    Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R.

    Endocrinology. 2002 Nov;143(11):4397-408.PMID: 12399437 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Effects of glucagon-like peptide-1 and exendins on kinase activity, glucose transport and lipid metabolism in adipocytes from normal and type-2 diabetic rats.

    Sancho V, Trigo MV, González N, Valverde I, Malaisse WJ, Villanueva-Peñacarrillo ML.

    J Mol Endocrinol. 2005 Aug;35(1):27-38.PMID: 16087719 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Follow-up of GK rats during prediabetes highlights increased insulin action and fat deposition despite low insulin secretion.

    Movassat J, Bailbé D, Lubrano-Berthelier C, Picarel-Blanchot F, Bertin E, Mourot J, Portha B.

    Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E168-75. Epub 2007 Nov 6.PMID: 17986628 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Beta-cell mass depletion precedes the onset of hyperglycaemia in the GK rat, a genetic model of non-insulin-dependent diabetes mellitus.

    Movassat J, Saulnier C, Portha B.

    Diabete Metab. 1995 Dec;21(5):365-70.PMID: 8586154 [PubMed - indexed for MEDLINE]Related articles

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