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    Results: 1 to 20 of 403

    1.

    Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter.

    Ban N, Yamada Y, Someya Y, Miyawaki K, Ihara Y, Hosokawa M, Toyokuni S, Tsuda K, Seino Y.

    Diabetes. 2002 May;51(5):1409-18.PMID: 11978637 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1alpha gene in a Korean family with MODY3.

    Kim KA, Kang K, Chi YI, Chang I, Lee MK, Kim KW, Shoelson SE, Lee MS.

    Diabetologia. 2003 May;46(5):721-7. Epub 2003 Apr 24.PMID: 12712243 [PubMed - indexed for MEDLINE]Related articles

    3.

    Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.

    Shih DQ, Screenan S, Munoz KN, Philipson L, Pontoglio M, Yaniv M, Polonsky KS, Stoffel M.

    Diabetes. 2001 Nov;50(11):2472-80.PMID: 11679424 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.

    Hansen SK, Párrizas M, Jensen ML, Pruhova S, Ek J, Boj SF, Johansen A, Maestro MA, Rivera F, Eiberg H, Andel M, Lebl J, Pedersen O, Ferrer J, Hansen T.

    J Clin Invest. 2002 Sep;110(6):827-33.PMID: 12235114 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Hepatocyte nuclear factor-1alpha inhibits insulin promoter factor 1-dependent transactivation of the human insulin gene.

    Yamakawa K, Yamasaki H, Ozaki M, Yamauchi MD, Fujita N, Abe T, Miyazoe H, Sera Y, Uotani S, Kawasaki E, Takino H, Yamaguchi Y, Eguchi K.

    Endocr Res. 2001 Feb-May;27(1-2):63-74.PMID: 11428722 [PubMed - indexed for MEDLINE]Related articles

    6.

    Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative.

    Yamagata K, Yang Q, Yamamoto K, Iwahashi H, Miyagawa J, Okita K, Yoshiuchi I, Miyazaki J, Noguchi T, Nakajima H, Namba M, Hanafusa T, Matsuzawa Y.

    Diabetes. 1998 Aug;47(8):1231-5.PMID: 9703322 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Transcriptional coactivators CBP and p300 cooperatively enhance HNF-1alpha-mediated expression of the albumin gene in hepatocytes.

    Dohda T, Kaneoka H, Inayoshi Y, Kamihira M, Miyake K, Iijima S.

    J Biochem. 2004 Sep;136(3):313-9.PMID: 15598887 [PubMed - indexed for MEDLINE]Related articles

    8.

    A pancreatic beta -cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta ), HNF-1alpha, and SPs transcription factors.

    Ben-Shushan E, Marshak S, Shoshkes M, Cerasi E, Melloul D.

    J Biol Chem. 2001 May 18;276(20):17533-40. Epub 2001 Feb 5.PMID: 11278466 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta.

    Okita K, Yang Q, Yamagata K, Hangenfeldt KA, Miyagawa J, Kajimoto Y, Nakajima H, Namba M, Wollheim CB, Hanafusa T, Matsuzawa Y.

    Biochem Biophys Res Commun. 1999 Sep 24;263(2):566-9.PMID: 10491332 [PubMed - indexed for MEDLINE]Related articles

    10.

    Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.

    Wang H, Maechler P, Hagenfeldt KA, Wollheim CB.

    EMBO J. 1998 Nov 16;17(22):6701-13.PMID: 9822613 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Regulation of apolipoprotein M gene expression by MODY3 gene hepatocyte nuclear factor-1alpha: haploinsufficiency is associated with reduced serum apolipoprotein M levels.

    Richter S, Shih DQ, Pearson ER, Wolfrum C, Fajans SS, Hattersley AT, Stoffel M.

    Diabetes. 2003 Dec;52(12):2989-95.PMID: 14633861 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets.

    Párrizas M, Maestro MA, Boj SF, Paniagua A, Casamitjana R, Gomis R, Rivera F, Ferrer J.

    Mol Cell Biol. 2001 May;21(9):3234-43.PMID: 11287626 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene. Cooperative role of hepatocyte nuclear factors 1alpha and 3beta.

    Cha JY, Kim H, Kim KS, Hur MW, Ahn Y.

    J Biol Chem. 2000 Jun 16;275(24):18358-65.PMID: 10748140 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Identification of seven novel nucleotide variants in the hepatocyte nuclear factor-1alpha (TCF1) promoter region in MODY patients.

    Godart F, Bellanné-Chantelot C, Clauin S, Gragnoli C, Abderrahmani A, Blanché H, Boutin P, Chèvre JC, Froguel P, Bailleul B.

    Hum Mutat. 2000;15(2):173-80.PMID: 10649494 [PubMed - indexed for MEDLINE]Related articles

    15.

    Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.

    Shih DQ, Heimesaat M, Kuwajima S, Stein R, Wright CV, Stoffel M.

    Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3818-23.PMID: 11904435 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Cloning and characterization of the human beta2-glycoprotein I (beta2-GPI) gene promoter: roles of the atypical TATA box and hepatic nuclear factor-1alpha in regulating beta2-GPI promoter activity.

    Wang HH, Chiang AN.

    Biochem J. 2004 Jun 1;380(Pt 2):455-63.PMID: 14984368 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the factor V111 gene.

    McGlynn LK, Mueller CR, Begbie M, Notley CR, Lillicrap D.

    Mol Cell Biol. 1996 May;16(5):1936-45.PMID: 8628260 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Identification and functional analysis of mutations in the hepatocyte nuclear factor-1alpha gene in anti-islet autoantibody-negative Japanese patients with type 1 diabetes.

    Kawasaki E, Sera Y, Yamakawa K, Abe T, Ozaki M, Uotani S, Ohtsu N, Takino H, Yamasaki H, Yamaguchi Y, Matsuura N, Eguchi K.

    J Clin Endocrinol Metab. 2000 Jan;85(1):331-5.PMID: 10634407 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.

    Frayling TM, Evans JC, Bulman MP, Pearson E, Allen L, Owen K, Bingham C, Hannemann M, Shepherd M, Ellard S, Hattersley AT.

    Diabetes. 2001 Feb;50 Suppl 1:S94-100.PMID: 11272211 [PubMed - indexed for MEDLINE]Related articles

    20.

    Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians.

    Baier LJ, Permana PA, Traurig M, Dobberfuhl A, Wiedrich C, Sutherland J, Thuillez P, Luczy-Bachman G, Hara M, Horikawa Y, Hinokio Y, Hanson RL, Bogardus C.

    Diabetes Care. 2000 Mar;23(3):302-4.PMID: 10868855 [PubMed - indexed for MEDLINE]Related articlesFree article

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